Matches in SemOpenAlex for { <https://semopenalex.org/work/W2137845793> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2137845793 endingPage "1249" @default.
- W2137845793 startingPage "1244" @default.
- W2137845793 abstract "ABSTRACT This study presents the data of an evaluation of the automated Nuclisens easyMAG and EasyQ systems versus the Roche AmpliPrep-AMPLICOR combination for testing of high-volume human immunodeficiency virus (HIV) load. This represents a follow-up of a previous study investigating the performance of the real-time Nuclisens assay using the semiautomated NucliSENS miniMAG extraction procedure. Three hundred eighteen patient samples were analyzed using both methods. The easyMAG-EasyQ HIV type 1 system has a higher sensitivity and broader dynamic range than the Cobas AmpliPrep-AMPLICOR system when the standard Roche assay is used alone, 25 to 3,000,000 IU/ml versus 400 to 750,000 HIV RNA copies/ml, respectively. There was significant correlation between the assays (0.93; P < 0.0001), with good accuracy (percent similarity mean μ = 96%), good precision (percent similarity standard deviation = 4.97%), and overall good agreement with a low percent similarity coefficient of variation of 5.17 to 6.11%. Bland-Altman analysis revealed that the AMPLICOR assay generated higher values than the EasyQ combination, with 95% of results within clinically acceptable limits. The throughput of samples was greatly improved using the easyMAG-EasyQ system, allowing 144 samples to be processed within 6 h. The potential for contamination has been dramatically reduced using the automated extraction system. Additional negative controls have been added to the kit to monitor for contamination based on the South African experience. This assay thus presents a real option for monitoring HIV load assays in high-volume testing environments." @default.
- W2137845793 created "2016-06-24" @default.
- W2137845793 creator A5044667291 @default.
- W2137845793 creator A5070408535 @default.
- W2137845793 creator A5075030692 @default.
- W2137845793 date "2007-04-01" @default.
- W2137845793 modified "2023-10-14" @default.
- W2137845793 title "Evaluation of the Performance of the Automated NucliSENS easyMAG and EasyQ Systems versus the Roche AmpliPrep-AMPLICOR Combination for High-Throughput Monitoring of Human Immunodeficiency Virus Load" @default.
- W2137845793 cites W2015795623 @default.
- W2137845793 cites W2031021336 @default.
- W2137845793 cites W2053084431 @default.
- W2137845793 cites W2056740555 @default.
- W2137845793 cites W2058982623 @default.
- W2137845793 cites W2163342767 @default.
- W2137845793 doi "https://doi.org/10.1128/jcm.01540-06" @default.
- W2137845793 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1865857" @default.
- W2137845793 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17267632" @default.
- W2137845793 hasPublicationYear "2007" @default.
- W2137845793 type Work @default.
- W2137845793 sameAs 2137845793 @default.
- W2137845793 citedByCount "28" @default.
- W2137845793 countsByYear W21378457932012 @default.
- W2137845793 countsByYear W21378457932013 @default.
- W2137845793 countsByYear W21378457932014 @default.
- W2137845793 countsByYear W21378457932015 @default.
- W2137845793 countsByYear W21378457932017 @default.
- W2137845793 countsByYear W21378457932018 @default.
- W2137845793 countsByYear W21378457932021 @default.
- W2137845793 countsByYear W21378457932023 @default.
- W2137845793 crossrefType "journal-article" @default.
- W2137845793 hasAuthorship W2137845793A5044667291 @default.
- W2137845793 hasAuthorship W2137845793A5070408535 @default.
- W2137845793 hasAuthorship W2137845793A5075030692 @default.
- W2137845793 hasBestOaLocation W21378457932 @default.
- W2137845793 hasConcept C121332964 @default.
- W2137845793 hasConcept C126322002 @default.
- W2137845793 hasConcept C142462285 @default.
- W2137845793 hasConcept C159047783 @default.
- W2137845793 hasConcept C185592680 @default.
- W2137845793 hasConcept C20556612 @default.
- W2137845793 hasConcept C2909597000 @default.
- W2137845793 hasConcept C3013748606 @default.
- W2137845793 hasConcept C43617362 @default.
- W2137845793 hasConcept C62520636 @default.
- W2137845793 hasConcept C71924100 @default.
- W2137845793 hasConcept C89838059 @default.
- W2137845793 hasConceptScore W2137845793C121332964 @default.
- W2137845793 hasConceptScore W2137845793C126322002 @default.
- W2137845793 hasConceptScore W2137845793C142462285 @default.
- W2137845793 hasConceptScore W2137845793C159047783 @default.
- W2137845793 hasConceptScore W2137845793C185592680 @default.
- W2137845793 hasConceptScore W2137845793C20556612 @default.
- W2137845793 hasConceptScore W2137845793C2909597000 @default.
- W2137845793 hasConceptScore W2137845793C3013748606 @default.
- W2137845793 hasConceptScore W2137845793C43617362 @default.
- W2137845793 hasConceptScore W2137845793C62520636 @default.
- W2137845793 hasConceptScore W2137845793C71924100 @default.
- W2137845793 hasConceptScore W2137845793C89838059 @default.
- W2137845793 hasIssue "4" @default.
- W2137845793 hasLocation W21378457931 @default.
- W2137845793 hasLocation W21378457932 @default.
- W2137845793 hasLocation W21378457933 @default.
- W2137845793 hasLocation W21378457934 @default.
- W2137845793 hasOpenAccess W2137845793 @default.
- W2137845793 hasPrimaryLocation W21378457931 @default.
- W2137845793 hasRelatedWork W1760802089 @default.
- W2137845793 hasRelatedWork W1945359667 @default.
- W2137845793 hasRelatedWork W1973460911 @default.
- W2137845793 hasRelatedWork W1988777930 @default.
- W2137845793 hasRelatedWork W2077563405 @default.
- W2137845793 hasRelatedWork W2137845793 @default.
- W2137845793 hasRelatedWork W2140412799 @default.
- W2137845793 hasRelatedWork W2147959297 @default.
- W2137845793 hasRelatedWork W3041916414 @default.
- W2137845793 hasRelatedWork W3044091667 @default.
- W2137845793 hasVolume "45" @default.
- W2137845793 isParatext "false" @default.
- W2137845793 isRetracted "false" @default.
- W2137845793 magId "2137845793" @default.
- W2137845793 workType "article" @default.