Matches in SemOpenAlex for { <https://semopenalex.org/work/W2137960961> ?p ?o ?g. }
- W2137960961 endingPage "e0136434" @default.
- W2137960961 startingPage "e0136434" @default.
- W2137960961 abstract "Chronic kidney disease (CKD) and hypertension are global public health problems associated with considerable morbidity, premature mortality and attendant healthcare costs. Previous studies have highlighted that non-invasive examination of the retinal microcirculation can detect microvascular pathology that is associated with systemic disorders of the circulatory system such as hypertension. We examined the associations between retinal vessel caliber (RVC) and fractal dimension (DF), with both hypertension and CKD in elderly Irish nuns.Data from 1233 participants in the cross-sectional observational Irish Nun Eye Study (INES) were assessed from digital photographs with a standardized protocol using computer-assisted software. Multivariate regression analyses were used to assess associations with hypertension and CKD, with adjustment for age, body mass index (BMI), refraction, fellow eye RVC, smoking, alcohol consumption, ischemic heart disease (IHD), cerebrovascular accident (CVA), diabetes and medication use.In total, 1122 (91%) participants (mean age: 76.3 [range: 56-100] years) had gradable retinal images of sufficient quality for blood vessel assessment. Hypertension was significantly associated with a narrower central retinal arteriolar equivalent (CRAE) in a fully adjusted analysis (P = 0.002; effect size = -2.16 μm; 95% confidence intervals [CI]: -3.51, -0.81 μm). No significant associations between other retinal vascular parameters and hypertension or between any retinal vascular parameters and CKD were found.Individuals with hypertension have significantly narrower retinal arterioles which may afford an earlier opportunity for tailored prevention and treatment options to optimize the structure and function of the microvasculature, providing additional clinical utility. No significant associations between retinal vascular parameters and CKD were detected." @default.
- W2137960961 created "2016-06-24" @default.
- W2137960961 creator A5010618682 @default.
- W2137960961 creator A5020682446 @default.
- W2137960961 creator A5034866208 @default.
- W2137960961 creator A5037199781 @default.
- W2137960961 creator A5048124766 @default.
- W2137960961 creator A5070082717 @default.
- W2137960961 creator A5090066163 @default.
- W2137960961 date "2015-09-01" @default.
- W2137960961 modified "2023-10-16" @default.
- W2137960961 title "Evaluation of the Retinal Vasculature in Hypertension and Chronic Kidney Disease in an Elderly Population of Irish Nuns" @default.
- W2137960961 cites W1594097016 @default.
- W2137960961 cites W1965899716 @default.
- W2137960961 cites W1970072800 @default.
- W2137960961 cites W1989428189 @default.
- W2137960961 cites W2000884512 @default.
- W2137960961 cites W2001318284 @default.
- W2137960961 cites W2001769141 @default.
- W2137960961 cites W2001885074 @default.
- W2137960961 cites W2005100068 @default.
- W2137960961 cites W2005741273 @default.
- W2137960961 cites W2008498491 @default.
- W2137960961 cites W2020900164 @default.
- W2137960961 cites W2022084537 @default.
- W2137960961 cites W2025315541 @default.
- W2137960961 cites W2025973019 @default.
- W2137960961 cites W2029785070 @default.
- W2137960961 cites W2033723052 @default.
- W2137960961 cites W2043093434 @default.
- W2137960961 cites W2046550489 @default.
- W2137960961 cites W2047888540 @default.
- W2137960961 cites W2048697771 @default.
- W2137960961 cites W2054205416 @default.
- W2137960961 cites W2057986538 @default.
- W2137960961 cites W2058239891 @default.
- W2137960961 cites W2061106058 @default.
- W2137960961 cites W2069914562 @default.
- W2137960961 cites W2070744197 @default.
- W2137960961 cites W2071592195 @default.
- W2137960961 cites W2081040499 @default.
- W2137960961 cites W2087547478 @default.
- W2137960961 cites W2088000704 @default.
- W2137960961 cites W2090496521 @default.
- W2137960961 cites W2101216584 @default.
- W2137960961 cites W2103852969 @default.
- W2137960961 cites W2104933282 @default.
- W2137960961 cites W2106050545 @default.
- W2137960961 cites W2110564525 @default.
- W2137960961 cites W2114646524 @default.
- W2137960961 cites W2115615802 @default.
- W2137960961 cites W2122639624 @default.
- W2137960961 cites W2127389619 @default.
- W2137960961 cites W2129859917 @default.
- W2137960961 cites W2130518501 @default.
- W2137960961 cites W2130745014 @default.
- W2137960961 cites W2130909498 @default.
- W2137960961 cites W2136125469 @default.
- W2137960961 cites W2141460031 @default.
- W2137960961 cites W2142821373 @default.
- W2137960961 cites W2142926367 @default.
- W2137960961 cites W2145632027 @default.
- W2137960961 cites W2151143109 @default.
- W2137960961 cites W2158318506 @default.
- W2137960961 cites W2166370747 @default.
- W2137960961 cites W2170789385 @default.
- W2137960961 cites W2171367439 @default.
- W2137960961 cites W2171996926 @default.
- W2137960961 cites W2329355442 @default.
- W2137960961 cites W2479433810 @default.
- W2137960961 cites W2484483641 @default.
- W2137960961 doi "https://doi.org/10.1371/journal.pone.0136434" @default.
- W2137960961 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4556713" @default.
- W2137960961 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26327531" @default.
- W2137960961 hasPublicationYear "2015" @default.
- W2137960961 type Work @default.
- W2137960961 sameAs 2137960961 @default.
- W2137960961 citedByCount "24" @default.
- W2137960961 countsByYear W21379609612016 @default.
- W2137960961 countsByYear W21379609612017 @default.
- W2137960961 countsByYear W21379609612018 @default.
- W2137960961 countsByYear W21379609612019 @default.
- W2137960961 countsByYear W21379609612020 @default.
- W2137960961 countsByYear W21379609612021 @default.
- W2137960961 countsByYear W21379609612022 @default.
- W2137960961 countsByYear W21379609612023 @default.
- W2137960961 crossrefType "journal-article" @default.
- W2137960961 hasAuthorship W2137960961A5010618682 @default.
- W2137960961 hasAuthorship W2137960961A5020682446 @default.
- W2137960961 hasAuthorship W2137960961A5034866208 @default.
- W2137960961 hasAuthorship W2137960961A5037199781 @default.
- W2137960961 hasAuthorship W2137960961A5048124766 @default.
- W2137960961 hasAuthorship W2137960961A5070082717 @default.
- W2137960961 hasAuthorship W2137960961A5090066163 @default.
- W2137960961 hasBestOaLocation W21379609611 @default.
- W2137960961 hasConcept C118487528 @default.
- W2137960961 hasConcept C126322002 @default.
- W2137960961 hasConcept C134018914 @default.