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- W2137966156 abstract "ABSTRACT Objective To compare early vs late administration of low‐dose aspirin on the risk of perinatal death and adverse perinatal outcome. Methods Databases were searched for keywords related to aspirin and pregnancy. Only randomized controlled trials that evaluated the prophylactic use of low‐dose aspirin (50–150 mg/day) during pregnancy were included. The primary outcome combined fetal and neonatal death. Pooled relative risks ( RR ) with their 95% CIs were compared according to gestational age at initiation of low‐dose aspirin (≤ 16 vs > 16 weeks of gestation). Results Out of 8377 citations, 42 studies (27 222 women) were included. Inclusion criteria were risk factors for pre‐eclampsia, including: nulliparity, multiple pregnancy, chronic hypertension, cardiovascular or endocrine disease, prior gestational hypertension or fetal growth restriction, and/or abnormal uterine artery Doppler. When compared with controls, low‐dose aspirin started at ≤ 16 weeks' gestation compared with low‐dose aspirin started at >16 weeks' gestation was associated with a greater reduction of perinatal death ( RR = 0.41 (95% CI , 0.19–0.92) vs 0.93 (95% CI , 0.73–1.19), P = 0.02), pre‐eclampsia ( RR = 0.47 (95% CI , 0.36–0.62) vs 0.78 (95% CI , 0.61–0.99), P < 0.01), severe pre‐eclampsia ( RR = 0.18 (95% CI , 0.08–0.41) vs 0.65 (95% CI , 0.40–1.07), P < 0.01), fetal growth restriction ( RR = 0.46 (95% CI , 0.33–0.64) vs 0.98 (95% CI , 0.88–1.08), P < 0.001) and preterm birth ( RR = 0.35 (95% CI , 0.22–0.57) vs 0.90 (95% CI , 0.83–0.97), P < 0.001). Conclusion Low‐dose aspirin initiated at ≤ 16 weeks of gestation is associated with a greater reduction of perinatal death and other adverse perinatal outcomes than when initiated at >16 weeks. Copyright © 2013 ISUOG. Published by John Wiley & Sons Ltd." @default.
- W2137966156 created "2016-06-24" @default.
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- W2137966156 date "2013-04-22" @default.
- W2137966156 modified "2023-10-18" @default.
- W2137966156 title "Prevention of perinatal death and adverse perinatal outcome using low-dose aspirin: a meta-analysis" @default.
- W2137966156 cites W1570638334 @default.
- W2137966156 cites W1580167980 @default.
- W2137966156 cites W1902505065 @default.
- W2137966156 cites W1965781378 @default.
- W2137966156 cites W1967984579 @default.
- W2137966156 cites W1980268488 @default.
- W2137966156 cites W1984323794 @default.
- W2137966156 cites W1985122146 @default.
- W2137966156 cites W1988433564 @default.
- W2137966156 cites W1992353506 @default.
- W2137966156 cites W1994779418 @default.
- W2137966156 cites W1996307378 @default.
- W2137966156 cites W2000135242 @default.
- W2137966156 cites W2001248679 @default.
- W2137966156 cites W2002269694 @default.
- W2137966156 cites W2003363140 @default.
- W2137966156 cites W2008532157 @default.
- W2137966156 cites W2014694623 @default.
- W2137966156 cites W2019678696 @default.
- W2137966156 cites W2021879241 @default.
- W2137966156 cites W2022461235 @default.
- W2137966156 cites W2025779964 @default.
- W2137966156 cites W2026162369 @default.
- W2137966156 cites W2029013982 @default.
- W2137966156 cites W2035223305 @default.
- W2137966156 cites W2040613067 @default.
- W2137966156 cites W2044192971 @default.
- W2137966156 cites W2049556573 @default.
- W2137966156 cites W2049576998 @default.
- W2137966156 cites W2053397656 @default.
- W2137966156 cites W2061459613 @default.
- W2137966156 cites W2061506872 @default.
- W2137966156 cites W2064122706 @default.
- W2137966156 cites W2070145124 @default.
- W2137966156 cites W2071338376 @default.
- W2137966156 cites W2073900532 @default.
- W2137966156 cites W2076686574 @default.
- W2137966156 cites W2077367449 @default.
- W2137966156 cites W2077421021 @default.
- W2137966156 cites W2080948021 @default.
- W2137966156 cites W2083348649 @default.
- W2137966156 cites W2085287091 @default.
- W2137966156 cites W2085958826 @default.
- W2137966156 cites W2089872515 @default.
- W2137966156 cites W2092021592 @default.
- W2137966156 cites W2099608443 @default.
- W2137966156 cites W2104895343 @default.
- W2137966156 cites W2107328434 @default.
- W2137966156 cites W2116316298 @default.
- W2137966156 cites W2117200377 @default.
- W2137966156 cites W2120306786 @default.
- W2137966156 cites W2126930838 @default.
- W2137966156 cites W2127608785 @default.
- W2137966156 cites W2130645342 @default.
- W2137966156 cites W2133931921 @default.
- W2137966156 cites W2157823046 @default.
- W2137966156 cites W2160084743 @default.
- W2137966156 cites W2171003562 @default.
- W2137966156 cites W2332128238 @default.
- W2137966156 cites W2340870097 @default.
- W2137966156 cites W2470097850 @default.
- W2137966156 cites W2982836077 @default.
- W2137966156 cites W3022893079 @default.
- W2137966156 cites W3023401627 @default.
- W2137966156 cites W4214559180 @default.
- W2137966156 cites W4248718627 @default.
- W2137966156 cites W4294215472 @default.
- W2137966156 doi "https://doi.org/10.1002/uog.12421" @default.
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