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- W2138045767 endingPage "958" @default.
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- W2138045767 abstract "For appropriate in vitro wear testing of prostheses and their biomaterials, the choice of lubricant is critical. Bovine serum is the lubricant recommended by several international standards for wear testing artificial joints and their biomaterials because the wear rate and wear mechanisms closely match clinical results of polyethylene bearings. The main problem with the use of bovine serum as a lubricant is protein degradation and precipitation formation, effects that are recognized as having a direct impact on wear processes. Hence, some researchers have questioned the validity of using bovine serum in simulator testing. This paper reviews the various lubricants used in laboratory wear studies and also the properties of the synovial fluid that the lubricant is trying to replicate. It is clear from the literature survey that the composition of bovine-serum-based lubricants does not match that of synovial fluid. In view of this conclusion, it is suggested that there is a need to develop an alternative lubricant that can replace bovine serum." @default.
- W2138045767 created "2016-06-24" @default.
- W2138045767 creator A5054321142 @default.
- W2138045767 creator A5085431209 @default.
- W2138045767 date "2011-07-18" @default.
- W2138045767 modified "2023-10-08" @default.
- W2138045767 title "Challenges associated with using bovine serum in wear testing orthopaedic biopolymers" @default.
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- W2138045767 doi "https://doi.org/10.1177/0954411911416047" @default.
- W2138045767 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22204117" @default.
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