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- W2138183755 abstract "Objective To determine if the severity of antenatally diagnosed hemorrhagic fetal brain insults and fetal stroke detected by ultrasound and magnetic resonance imaging (MRI) predicts postnatal neurodevelopmental prognosis. Methods The in-utero presentation and postnatal neurodevelopmental outcome of sonographically detected subdural hematoma or fetal stroke presenting as intraventricular hemorrhage (IVH) or intraparenchymal brain hemorrhage were investigated. Results Of 33 fetuses diagnosed with hemorrhagic brain lesions, 17 were electively terminated and two suffered intrauterine fetal demise. Thirteen were liveborn, seven by Cesarean delivery and six by spontaneous vaginal delivery. One case was lost to follow-up. Eight neonates had moderate to severe neurological deficit by a mean age of 35 (range, 6–96) months. One died at 2 months of age. These nine were diagnosed with Grade III–IV IVH in utero. Four neonates had normal neurological outcome by a mean age of 41 (range, 30–48) months; these four were diagnosed with subdural hematoma (n = 1) or Grade I–II IVH (n = 3) in utero. Fourteen cases were followed up with MRI, which confirmed ultrasound findings in 10 (71%) cases. In three (21%) cases MRI diagnosis was more accurate and the severity of grading was greater than that obtained on ultrasound imaging. Unilateral left hemispheric lesions were much more common than right-sided lesions (13 vs. 1, respectively). Conclusions An antenatal sonographic diagnosis of fetal stroke with IVH Grade III–IV or with brain parenchymal involvement appears to be associated with poor neurological outcome. MRI may contribute to the accuracy of diagnosis, particularly in Grade II and III lesions. Left-sided unilateral lesions are more common than right-sided ones. Copyright © 2005 ISUOG. Published by John Wiley & Sons, Ltd." @default.
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- W2138183755 date "2005-08-05" @default.
- W2138183755 modified "2023-10-09" @default.
- W2138183755 title "Fetal intracranial hemorrhage (fetal stroke): does grade matter?" @default.
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- W2138183755 doi "https://doi.org/10.1002/uog.1969" @default.
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