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- W2138183784 abstract "Previous studies have related cardiovascular risk factors—estimated before pregnancy—to birth weight, and also have found an association between low birth weight and an increased risk of maternal cardiovascular death. This study used linear regression analysis to prospectively examine associations between blood pressure and blood lipid levels measured before conception, and birth weight adjusted for gestational age of the offspring. The study population included 3461 women whose deliveries were listed in the Medical Birth Registry of Norway up to the year 2005. Participants had a mean age of 30.2 years at the time of delivery. After adjusting for age, smoking status, height, parity, socioeconomic status, and prepregnancy body mass index, high maternal systolic blood pressure was associated with low birth weight for gestational age. A similar but less marked association was found between low birth weight and prepregnancy diastolic blood pressure. Unfavorable levels of total serum cholesterol, high-density lipoprotein cholesterol, triglycerides, and blood glucose were positively associated with birth weight for gestational age. The association between blood lipid levels and birth weight persisted after excluding pregnancies complicated by preeclampsia. The findings in this prospective study suggest that low birth weight, as well as high birth weight, may be an indicator of increased maternal cardiovascular risk. Women with relatively high blood pressure tended to deliver small infants. At the same time, those with unfavorable lipid levels tended to have large babies, suggesting reduced glucose tolerance." @default.
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- W2138183784 date "2008-04-01" @default.
- W2138183784 modified "2023-09-24" @default.
- W2138183784 title "Associations of Prepregnancy Cardiovascular Risk Factors With the Offspring’s Birth Weight" @default.
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- W2138183784 doi "https://doi.org/10.1097/01.ogx.0000308995.36406.bd" @default.
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