Matches in SemOpenAlex for { <https://semopenalex.org/work/W2138214924> ?p ?o ?g. }
- W2138214924 endingPage "1728" @default.
- W2138214924 startingPage "1719" @default.
- W2138214924 abstract "Abstract Using 2‐DE, transcriptional gene fusions and cell cytotoxicity assays, we followed changes in the Bacillus cereus strain ATCC14579 secretome, gene expression and culture supernatant cytotoxicity from the end of the vegetative phase up to 5 h after entry into the stationary phase. The concentration of each of the 22 proteins in the culture supernatant was determined at various times. In addition, the stability of the proteins was studied. Fifteen of these proteins, including 14 members of the virulence regulon PlcR, were known or predicted to be secreted. All of the secreted proteins reached a maximum concentration during early stationary phase, but there were significant differences in the kinetics of their concentrations. The time courses of protein concentrations were in agreement with gene expression data, except for cytotoxin CytK, which was unstable, and for the metalloprotease InhA1. Supernatant cytoxicity also peaked in early stationary phase, and the kinetics of cytotoxicity paralleled the time course of concentration of the PlcR‐controlled toxin, CytK. Our concomitant study of the time course of protein concentrations, gene expression and supernatant cytotoxicity reveals that the pathogenic potential of B. cereus peaks during the transition state. It also suggests that there is diversity in the regulation of gene expression within the PlcR regulon." @default.
- W2138214924 created "2016-06-24" @default.
- W2138214924 creator A5010484045 @default.
- W2138214924 creator A5042692067 @default.
- W2138214924 creator A5052885886 @default.
- W2138214924 creator A5066276934 @default.
- W2138214924 creator A5067081782 @default.
- W2138214924 creator A5070395172 @default.
- W2138214924 creator A5081938031 @default.
- W2138214924 creator A5088848983 @default.
- W2138214924 date "2007-05-01" @default.
- W2138214924 modified "2023-10-02" @default.
- W2138214924 title "Growth-related variations in theBacillus cereus secretome" @default.
- W2138214924 cites W110247251 @default.
- W2138214924 cites W1512506435 @default.
- W2138214924 cites W1573664132 @default.
- W2138214924 cites W1656893325 @default.
- W2138214924 cites W1835434814 @default.
- W2138214924 cites W1981563187 @default.
- W2138214924 cites W1987680218 @default.
- W2138214924 cites W1995782802 @default.
- W2138214924 cites W2001763105 @default.
- W2138214924 cites W2014917430 @default.
- W2138214924 cites W2047064510 @default.
- W2138214924 cites W2050523158 @default.
- W2138214924 cites W2056372200 @default.
- W2138214924 cites W2070307502 @default.
- W2138214924 cites W2077914268 @default.
- W2138214924 cites W2083604712 @default.
- W2138214924 cites W2087828356 @default.
- W2138214924 cites W2088313841 @default.
- W2138214924 cites W2092740268 @default.
- W2138214924 cites W2096324489 @default.
- W2138214924 cites W2100257149 @default.
- W2138214924 cites W2110971393 @default.
- W2138214924 cites W2111086397 @default.
- W2138214924 cites W2116788456 @default.
- W2138214924 cites W2118012957 @default.
- W2138214924 cites W2120266240 @default.
- W2138214924 cites W2122020611 @default.
- W2138214924 cites W2122145390 @default.
- W2138214924 cites W2123284949 @default.
- W2138214924 cites W2123641345 @default.
- W2138214924 cites W2129974859 @default.
- W2138214924 cites W2132658744 @default.
- W2138214924 cites W2149545014 @default.
- W2138214924 cites W2152025039 @default.
- W2138214924 cites W2152105363 @default.
- W2138214924 cites W2164029628 @default.
- W2138214924 cites W2166383488 @default.
- W2138214924 cites W4293247451 @default.
- W2138214924 doi "https://doi.org/10.1002/pmic.200600502" @default.
- W2138214924 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17486558" @default.
- W2138214924 hasPublicationYear "2007" @default.
- W2138214924 type Work @default.
- W2138214924 sameAs 2138214924 @default.
- W2138214924 citedByCount "50" @default.
- W2138214924 countsByYear W21382149242012 @default.
- W2138214924 countsByYear W21382149242013 @default.
- W2138214924 countsByYear W21382149242014 @default.
- W2138214924 countsByYear W21382149242015 @default.
- W2138214924 countsByYear W21382149242016 @default.
- W2138214924 countsByYear W21382149242018 @default.
- W2138214924 countsByYear W21382149242019 @default.
- W2138214924 countsByYear W21382149242020 @default.
- W2138214924 countsByYear W21382149242021 @default.
- W2138214924 countsByYear W21382149242022 @default.
- W2138214924 countsByYear W21382149242023 @default.
- W2138214924 crossrefType "journal-article" @default.
- W2138214924 hasAuthorship W2138214924A5010484045 @default.
- W2138214924 hasAuthorship W2138214924A5042692067 @default.
- W2138214924 hasAuthorship W2138214924A5052885886 @default.
- W2138214924 hasAuthorship W2138214924A5066276934 @default.
- W2138214924 hasAuthorship W2138214924A5067081782 @default.
- W2138214924 hasAuthorship W2138214924A5070395172 @default.
- W2138214924 hasAuthorship W2138214924A5081938031 @default.
- W2138214924 hasAuthorship W2138214924A5088848983 @default.
- W2138214924 hasConcept C104317684 @default.
- W2138214924 hasConcept C109316439 @default.
- W2138214924 hasConcept C150194340 @default.
- W2138214924 hasConcept C153911025 @default.
- W2138214924 hasConcept C202751555 @default.
- W2138214924 hasConcept C2777118263 @default.
- W2138214924 hasConcept C523546767 @default.
- W2138214924 hasConcept C54355233 @default.
- W2138214924 hasConcept C55493867 @default.
- W2138214924 hasConcept C60987743 @default.
- W2138214924 hasConcept C62361671 @default.
- W2138214924 hasConcept C86803240 @default.
- W2138214924 hasConcept C89423630 @default.
- W2138214924 hasConceptScore W2138214924C104317684 @default.
- W2138214924 hasConceptScore W2138214924C109316439 @default.
- W2138214924 hasConceptScore W2138214924C150194340 @default.
- W2138214924 hasConceptScore W2138214924C153911025 @default.
- W2138214924 hasConceptScore W2138214924C202751555 @default.
- W2138214924 hasConceptScore W2138214924C2777118263 @default.
- W2138214924 hasConceptScore W2138214924C523546767 @default.
- W2138214924 hasConceptScore W2138214924C54355233 @default.