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- W2138215354 abstract "In the presence of autologous complement, maximal phagocytosis of Candida albicans blastospores of both a virulent and attenuated strain by human neutrophils in a monolayer assay was achieved after 30 min. The proportion of phagocytes containing intracellular blastospores was 33-36% with an average of 1.5 blastospores per phagocyte. In contrast to the attenuated strain of C. albicans, the virulent strain resisted opsonization by C-reactive protein (CRP) and of those blastospores ingested, only 8% were killed. These findings support the concept that CRP may play a protective role in candidosis independent of complement. The fate of strains of different virulence may be a result of differences in CRP receptors or killing mechanisms." @default.
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- W2138215354 date "1991-11-01" @default.
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- W2138215354 title "Opsonic effect of C-reactive protein on phagocytosis and intracellular killing of virulent and attenuated strains of<i>Candida albicans</i>by human neutrophils" @default.
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- W2138215354 doi "https://doi.org/10.1111/j.1574-6968.1991.tb04259.x" @default.
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