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- W2138236780 abstract "We present a detailed investigation on the feasibility of on-line dynamic light scattering measurements of colloidal sizes in a pressure-driven microfluidic flow. We review some theoretical arguments showing that such experiments are difficult to perform due to the Poiseuille flow that induces interferences of different Doppler shifts. Such a theoretical approach is however very useful to figure out the range of parameters where on-line size measurements are possible. We then build a dynamic light scattering setup around a microfluidic chip that enables us to estimate the size of Brownian scatterers flowing in PDMS-based microchannels, thus validating experimentally the theoretical estimations. We finally present a microfluidic chip that can mix two reactants in ≈200 ms, and allows size measurements using dynamic light scattering at about 300 ms after complete mixing. Two applications are presented: the continuous monitoring of the viscosity of a two-fluid mixture, and the electrostatic co-assembly of oppositely charged nanoparticles and block copolymers." @default.
- W2138236780 created "2016-06-24" @default.
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- W2138236780 date "2009-01-01" @default.
- W2138236780 modified "2023-10-13" @default.
- W2138236780 title "Microfluidics with on-line dynamic light scattering for size measurements" @default.
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- W2138236780 doi "https://doi.org/10.1039/b906514h" @default.
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