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- W2138248146 abstract "There is a growing interest for vitamin D in the medical and scientific community as well as in the public medias as illustrated by a huge number of publications. Most experts claim that vitamin D deficiency/insufficiency is widespread with potential important public health consequences. It may seem surprising for many persons that a deficiency in a vitamin may be so frequent in countries where food is so diversified and easily available. In fact, vitamin D is not a vitamin stricto sensu as it is mainly synthesized in the skin under the action of UVB rays, while its food sources are scarce. Furthermore, UVB rays are absent during a marked part of the year at latitudes greater than 35-40°, while pollution and cloud cover reduce the number of UVB reaching the earth, and many factors such as age, skin pigmentation, covering clothes, sun creams reduce the capacity of the skin to synthesize vitamin D3. Vitamin D must be hydroxylated to form 1,25dihydroxyvitamin D (1,25OH2D), the active metabolite. As 1,25OH2D is released into the bloodstream and binds to a receptor present in several distant tissues, it may be considered as a hormone, vitamin D being thus a pre-prohormone. In the present article, we review briefly the metabolism and various effects of vitamin D as well as the vitamin D assays and vitamin D treatments. We define vitamin D deficiency/insufficiency considering separately the population and the patient level and propose our opinion about which patients may benefit from vitamin D testing. Keywords: Vitamin D, 25-hydroxyvitamin D, Calcitriol, Parathyroid hormone, Immunoassay, Mass spectrometry, Reference values, METABOLISM, Calcitriol, fortified food" @default.
- W2138248146 created "2016-06-24" @default.
- W2138248146 creator A5061471977 @default.
- W2138248146 creator A5081877056 @default.
- W2138248146 date "2012-12-01" @default.
- W2138248146 modified "2023-10-18" @default.
- W2138248146 title "Supplementation, Optimal Status, and Analytical Determination of Vitamin D: Where are we Standing in 2012?" @default.
- W2138248146 cites W1911104948 @default.
- W2138248146 cites W1956294817 @default.
- W2138248146 cites W1968511285 @default.
- W2138248146 cites W1970334227 @default.
- W2138248146 cites W1970447061 @default.
- W2138248146 cites W1971801813 @default.
- W2138248146 cites W1974125594 @default.
- W2138248146 cites W1976233245 @default.
- W2138248146 cites W1977746554 @default.
- W2138248146 cites W1985226482 @default.
- W2138248146 cites W1986039748 @default.
- W2138248146 cites W1987296634 @default.
- W2138248146 cites W1988221010 @default.
- W2138248146 cites W1989499166 @default.
- W2138248146 cites W1996563641 @default.
- W2138248146 cites W1996787056 @default.
- W2138248146 cites W2006043449 @default.
- W2138248146 cites W2017836012 @default.
- W2138248146 cites W2018943212 @default.
- W2138248146 cites W2019962813 @default.
- W2138248146 cites W2020202822 @default.
- W2138248146 cites W2021636579 @default.
- W2138248146 cites W2022505313 @default.
- W2138248146 cites W2025012084 @default.
- W2138248146 cites W2031450649 @default.
- W2138248146 cites W2032442888 @default.
- W2138248146 cites W2033039566 @default.
- W2138248146 cites W2036841307 @default.
- W2138248146 cites W2042120769 @default.
- W2138248146 cites W2042517103 @default.
- W2138248146 cites W2049310368 @default.
- W2138248146 cites W2049710290 @default.
- W2138248146 cites W2068280073 @default.
- W2138248146 cites W2070663535 @default.
- W2138248146 cites W2070981379 @default.
- W2138248146 cites W2071302258 @default.
- W2138248146 cites W2093206323 @default.
- W2138248146 cites W2099665543 @default.
- W2138248146 cites W2100297809 @default.
- W2138248146 cites W2101687723 @default.
- W2138248146 cites W2102960021 @default.
- W2138248146 cites W2104062693 @default.
- W2138248146 cites W2106647095 @default.
- W2138248146 cites W2108825111 @default.
- W2138248146 cites W2109452366 @default.
- W2138248146 cites W2110242624 @default.
- W2138248146 cites W2112056917 @default.
- W2138248146 cites W2114382551 @default.
- W2138248146 cites W2118540989 @default.
- W2138248146 cites W2119682509 @default.
- W2138248146 cites W2121080036 @default.
- W2138248146 cites W2124070987 @default.
- W2138248146 cites W2125793849 @default.
- W2138248146 cites W2126574528 @default.
- W2138248146 cites W2126617070 @default.
- W2138248146 cites W2127609720 @default.
- W2138248146 cites W2128292128 @default.
- W2138248146 cites W2129235106 @default.
- W2138248146 cites W2131264460 @default.
- W2138248146 cites W2132096646 @default.
- W2138248146 cites W2142104529 @default.
- W2138248146 cites W2144548438 @default.
- W2138248146 cites W2146218824 @default.
- W2138248146 cites W2149425411 @default.
- W2138248146 cites W2150559716 @default.
- W2138248146 cites W2153059487 @default.
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- W2138248146 cites W2160986037 @default.
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- W2138248146 cites W2165144872 @default.
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- W2138248146 cites W2171086243 @default.
- W2138248146 cites W2171551201 @default.
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- W2138248146 doi "https://doi.org/10.2174/1871520611307010036" @default.
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