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- W2138249433 abstract "Circadian day/night variations have been evidenced in all major groups of organisms and at all levels of organisation of the organism. Circadian intra-individual variations are known for a number of analyses in serum including tumour-associated markers.1-4 It was suggested that the serum levels of cysteine proteinases and their inhibitors may be of clinical importance for prognosis and diagnosis in cancer.5 Since known circadian rhythms are important for choosing the best sampling time, interpretation of the results of a diagnostic test, patient monitoring, and timing of a therapy, our objective was to establish 24-h variations of cysteine proteinases, cathepsins B, H, L, and their low molecular weight inhibitors, stefin A, stefin B, and cystatin C, in sera from healthy subjects." @default.
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- W2138249433 date "2002-01-06" @default.
- W2138249433 modified "2023-09-24" @default.
- W2138249433 title "Circadian rhythms of cysteine proteinases and cystatins, potential tumour markers, in normal sera" @default.
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