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- W2138278340 endingPage "5159" @default.
- W2138278340 startingPage "5153" @default.
- W2138278340 abstract "Abstract CCR7 was described initially as a potent leukocyte chemotactic receptor that was later shown to be responsible of directing the migration of dendritic cells (DCs) to the lymph nodes where these cells play an important role in the initiation of the immune response. Recently, a variety of reports have indicated that, apart from chemotaxis, CCR7 controls the cytoarchitecture, the rate of endocytosis, the survival, the migratory speed, and the maturation of the DCs. Some of these functions of CCR7 and additional ones also have been described in other cell types. Herein we discuss how this receptor may contribute to modulate the immune response by regulating different functions in DCs. Finally, we also suggest a possible mechanism whereby CCR7 may control its multiple tasks in these cells." @default.
- W2138278340 created "2016-06-24" @default.
- W2138278340 creator A5065051928 @default.
- W2138278340 creator A5070260023 @default.
- W2138278340 creator A5082292044 @default.
- W2138278340 date "2006-05-01" @default.
- W2138278340 modified "2023-10-18" @default.
- W2138278340 title "The Multiple Personalities of the Chemokine Receptor CCR7 in Dendritic Cells" @default.
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- W2138278340 doi "https://doi.org/10.4049/jimmunol.176.9.5153" @default.
- W2138278340 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16621978" @default.
- W2138278340 hasPublicationYear "2006" @default.
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