FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2138335172> ?p ?o ?g. }

• W2138335172 endingPage "2084" @default.
• W2138335172 startingPage "2075" @default.
• W2138335172 abstract "Heat acclimation improves the tolerance of organisms to severe heat stress. Our previous work showed that in Arabidopsis (Arabidopsis thaliana), the memory of heat acclimation treatment decayed faster in the absence of the heat-stress-associated 32-kD protein HSA32, a heat-induced protein predominantly found in plants. The HSA32 null mutant attains normal short-term acquired thermotolerance but is defective in long-term acquired thermotolerance. To further explore this phenomenon, we isolated Arabidopsis defective in long-term acquired thermotolerance (dlt) mutants using a forward genetic screen. Two recessive missense alleles, dlt1-1 and dlt1-2, encode the molecular chaperone heat shock protein101 (HSP101). Results of immunoblot analyses suggest that HSP101 enhances the translation of HSA32 during recovery after heat treatment, and in turn, HSA32 retards the decay of HSP101. The dlt1-1 mutation has little effect on HSP101 chaperone activity and thermotolerance function but compromises the regulation of HSA32. In contrast, dlt1-2 impairs the chaperone activity and thermotolerance function of HSP101 but not the regulation of HSA32. These results suggest that HSP101 has a dual function, which could be decoupled by the mutations. Pulse-chase analysis showed that HSP101 degraded faster in the absence of HSA32. The autophagic proteolysis inhibitor E-64d, but not the proteasome inhibitor MG132, inhibited the degradation of HSP101. Ectopic expression of HSA32 confirmed its effect on the decay of HSP101 at the posttranscriptional level and showed that HSA32 was not sufficient to confer long-term acquired thermotolerance when the HSP101 level was low. Taken together, we propose that a positive feedback loop between HSP101 and HSA32 at the protein level is a novel mechanism for prolonging the memory of heat acclimation." @default.
• W2138335172 created "2016-06-24" @default.
• W2138335172 creator A5006654632 @default.
• W2138335172 creator A5007008176 @default.
• W2138335172 creator A5008834868 @default.
• W2138335172 creator A5015846994 @default.
• W2138335172 creator A5018606116 @default.
• W2138335172 creator A5032649553 @default.
• W2138335172 creator A5061926718 @default.
• W2138335172 date "2013-02-25" @default.
• W2138335172 modified "2023-10-18" @default.
• W2138335172 title "Interplay between Heat Shock Proteins HSP101 and HSA32 Prolongs Heat Acclimation Memory Posttranscriptionally in Arabidopsis " @default.
• W2138335172 cites W1510504215 @default.
• W2138335172 cites W1524650834 @default.
• W2138335172 cites W1941634103 @default.
• W2138335172 cites W1969445057 @default.
• W2138335172 cites W1974735434 @default.
• W2138335172 cites W1980431043 @default.
• W2138335172 cites W1987451918 @default.
• W2138335172 cites W1989361920 @default.
• W2138335172 cites W1989532291 @default.
• W2138335172 cites W1994730950 @default.
• W2138335172 cites W2001597843 @default.
• W2138335172 cites W2010641260 @default.
• W2138335172 cites W2010678358 @default.
• W2138335172 cites W2013495163 @default.
• W2138335172 cites W2025001748 @default.
• W2138335172 cites W2032625890 @default.
• W2138335172 cites W2033017459 @default.
• W2138335172 cites W2034714545 @default.
• W2138335172 cites W2046244086 @default.
• W2138335172 cites W2055538117 @default.
• W2138335172 cites W2058011811 @default.
• W2138335172 cites W2059277971 @default.
• W2138335172 cites W2060687391 @default.
• W2138335172 cites W2063023687 @default.
• W2138335172 cites W2064931700 @default.
• W2138335172 cites W2066133211 @default.
• W2138335172 cites W2081837436 @default.
• W2138335172 cites W2096612505 @default.
• W2138335172 cites W2104084141 @default.
• W2138335172 cites W2116122104 @default.
• W2138335172 cites W2117843484 @default.
• W2138335172 cites W2122070718 @default.
• W2138335172 cites W2127204797 @default.
• W2138335172 cites W2132354673 @default.
• W2138335172 cites W2132632499 @default.
• W2138335172 cites W2150231361 @default.
• W2138335172 cites W2155335606 @default.
• W2138335172 cites W2161152190 @default.
• W2138335172 cites W2166668335 @default.
• W2138335172 cites W2166898944 @default.
• W2138335172 cites W2167007018 @default.
• W2138335172 cites W2170566884 @default.
• W2138335172 cites W2320007870 @default.
• W2138335172 doi "https://doi.org/10.1104/pp.112.212589" @default.
• W2138335172 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3613477" @default.
• W2138335172 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23439916" @default.
• W2138335172 hasPublicationYear "2013" @default.
• W2138335172 type Work @default.
• W2138335172 sameAs 2138335172 @default.
• W2138335172 citedByCount "76" @default.
• W2138335172 countsByYear W21383351722014 @default.
• W2138335172 countsByYear W21383351722015 @default.
• W2138335172 countsByYear W21383351722016 @default.
• W2138335172 countsByYear W21383351722017 @default.
• W2138335172 countsByYear W21383351722018 @default.
• W2138335172 countsByYear W21383351722019 @default.
• W2138335172 countsByYear W21383351722020 @default.
• W2138335172 countsByYear W21383351722021 @default.
• W2138335172 countsByYear W21383351722022 @default.
• W2138335172 countsByYear W21383351722023 @default.
• W2138335172 crossrefType "journal-article" @default.
• W2138335172 hasAuthorship W2138335172A5006654632 @default.
• W2138335172 hasAuthorship W2138335172A5007008176 @default.
• W2138335172 hasAuthorship W2138335172A5008834868 @default.
• W2138335172 hasAuthorship W2138335172A5015846994 @default.
• W2138335172 hasAuthorship W2138335172A5018606116 @default.
• W2138335172 hasAuthorship W2138335172A5032649553 @default.
• W2138335172 hasAuthorship W2138335172A5061926718 @default.
• W2138335172 hasBestOaLocation W21383351721 @default.
• W2138335172 hasConcept C104317684 @default.
• W2138335172 hasConcept C137984847 @default.
• W2138335172 hasConcept C142724271 @default.
• W2138335172 hasConcept C143065580 @default.
• W2138335172 hasConcept C205260736 @default.
• W2138335172 hasConcept C2775962898 @default.
• W2138335172 hasConcept C2777174735 @default.
• W2138335172 hasConcept C2779491563 @default.
• W2138335172 hasConcept C54355233 @default.
• W2138335172 hasConcept C71924100 @default.
• W2138335172 hasConcept C86803240 @default.
• W2138335172 hasConcept C95444343 @default.
• W2138335172 hasConceptScore W2138335172C104317684 @default.
• W2138335172 hasConceptScore W2138335172C137984847 @default.
• W2138335172 hasConceptScore W2138335172C142724271 @default.
• W2138335172 hasConceptScore W2138335172C143065580 @default.
• W2138335172 hasConceptScore W2138335172C205260736 @default.

• next