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- W2138344131 abstract "Thymidylate synthase converts deoxyuridylate to deoxythymidylate. The thyA gene has been cloned and sequenced from Neisseria gonorrhoeae MS11. This gene has an open reading frame of 795-801 bp and encodes a product which shares 71% identity with its Escherichia coli homolog. Unlike its E. coli counterpart, gonococcal thyA has a large, upstream transcribed region (300+ bp) that lacks a translatable reading frame. Gonococcal thyA is capable of complementing an E. coli thyA null mutant and shares similar levels of sensitivity with trimethoprim." @default.
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- W2138344131 date "2006-01-17" @default.
- W2138344131 modified "2023-10-17" @default.
- W2138344131 title "Identification and characterization of thymidylate synthase from Neisseria gonorrhoeae" @default.
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- W2138344131 doi "https://doi.org/10.1111/j.1574-6968.1997.tb12574.x" @default.
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