Matches in SemOpenAlex for { <https://semopenalex.org/work/W2138435704> ?p ?o ?g. }
- W2138435704 endingPage "608" @default.
- W2138435704 startingPage "601" @default.
- W2138435704 abstract "This study is the first to examine the increased apoptosis in the adult rat ovary after lactational exposure to coumestrol (COU), a potent phytoestrogen. Lactating dams were gavaged at doses of 0.01, 0.1, 1, and 10 mg/kg COU during the lactation period and the reproductive effects of female pups were investigated in young adults. Rats were sacrificed at postnatal days (PND) 81–84. Ovarian weights were reduced significantly at 0.1 and 1.0 mg/kg COU. The reduction in the ovarian weight occurred in parallel with an increase in the apoptosis at PND 135–140. A marked dose-dependent increase in the expressions of active caspase-3 and -7 was observed in ovarian granulosa cells. Immunostaining for active caspase-3 and the TUNEL staining of apoptotic cells were also increased in ovaries exposed to COU in a dose-dependent manner. These results suggest new sights into the effect of lactational exposure to COU on the female reproductive health." @default.
- W2138435704 created "2016-06-24" @default.
- W2138435704 creator A5016801217 @default.
- W2138435704 creator A5024626009 @default.
- W2138435704 creator A5050955196 @default.
- W2138435704 creator A5051627423 @default.
- W2138435704 creator A5055854951 @default.
- W2138435704 creator A5061629380 @default.
- W2138435704 creator A5064363666 @default.
- W2138435704 creator A5070495431 @default.
- W2138435704 creator A5079274855 @default.
- W2138435704 creator A5083189507 @default.
- W2138435704 creator A5085705153 @default.
- W2138435704 creator A5090985856 @default.
- W2138435704 date "2009-01-23" @default.
- W2138435704 modified "2023-10-18" @default.
- W2138435704 title "Lactational coumestrol exposure increases ovarian apoptosis in adult rats" @default.
- W2138435704 cites W1933411778 @default.
- W2138435704 cites W1963728121 @default.
- W2138435704 cites W1967199332 @default.
- W2138435704 cites W1967912613 @default.
- W2138435704 cites W1970230480 @default.
- W2138435704 cites W1971932969 @default.
- W2138435704 cites W1979078001 @default.
- W2138435704 cites W1985470303 @default.
- W2138435704 cites W1988518686 @default.
- W2138435704 cites W1992350671 @default.
- W2138435704 cites W1997005484 @default.
- W2138435704 cites W1997801508 @default.
- W2138435704 cites W2001414375 @default.
- W2138435704 cites W2015931145 @default.
- W2138435704 cites W2017440399 @default.
- W2138435704 cites W2019519527 @default.
- W2138435704 cites W2021029817 @default.
- W2138435704 cites W2026636862 @default.
- W2138435704 cites W2027349642 @default.
- W2138435704 cites W2027533003 @default.
- W2138435704 cites W2030575224 @default.
- W2138435704 cites W2034993146 @default.
- W2138435704 cites W2040133649 @default.
- W2138435704 cites W2043310375 @default.
- W2138435704 cites W2045257049 @default.
- W2138435704 cites W2048865313 @default.
- W2138435704 cites W2049970571 @default.
- W2138435704 cites W2052906091 @default.
- W2138435704 cites W2055759603 @default.
- W2138435704 cites W2056155809 @default.
- W2138435704 cites W2058011514 @default.
- W2138435704 cites W2059095298 @default.
- W2138435704 cites W2077754316 @default.
- W2138435704 cites W2082259697 @default.
- W2138435704 cites W2084158084 @default.
- W2138435704 cites W2098640833 @default.
- W2138435704 cites W2103591161 @default.
- W2138435704 cites W2103653149 @default.
- W2138435704 cites W2119245156 @default.
- W2138435704 cites W2121853087 @default.
- W2138435704 cites W2132686612 @default.
- W2138435704 cites W2137968666 @default.
- W2138435704 cites W2148321928 @default.
- W2138435704 cites W2152001263 @default.
- W2138435704 cites W2157999078 @default.
- W2138435704 cites W2159583680 @default.
- W2138435704 cites W2165359170 @default.
- W2138435704 cites W2169328139 @default.
- W2138435704 cites W2181430872 @default.
- W2138435704 cites W2314440494 @default.
- W2138435704 cites W2317363980 @default.
- W2138435704 cites W2325707043 @default.
- W2138435704 cites W4235141812 @default.
- W2138435704 cites W4238018220 @default.
- W2138435704 doi "https://doi.org/10.1007/s00204-008-0400-0" @default.
- W2138435704 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2695544" @default.
- W2138435704 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19165469" @default.
- W2138435704 hasPublicationYear "2009" @default.
- W2138435704 type Work @default.
- W2138435704 sameAs 2138435704 @default.
- W2138435704 citedByCount "19" @default.
- W2138435704 countsByYear W21384357042012 @default.
- W2138435704 countsByYear W21384357042013 @default.
- W2138435704 countsByYear W21384357042014 @default.
- W2138435704 countsByYear W21384357042016 @default.
- W2138435704 countsByYear W21384357042017 @default.
- W2138435704 countsByYear W21384357042019 @default.
- W2138435704 crossrefType "journal-article" @default.
- W2138435704 hasAuthorship W2138435704A5016801217 @default.
- W2138435704 hasAuthorship W2138435704A5024626009 @default.
- W2138435704 hasAuthorship W2138435704A5050955196 @default.
- W2138435704 hasAuthorship W2138435704A5051627423 @default.
- W2138435704 hasAuthorship W2138435704A5055854951 @default.
- W2138435704 hasAuthorship W2138435704A5061629380 @default.
- W2138435704 hasAuthorship W2138435704A5064363666 @default.
- W2138435704 hasAuthorship W2138435704A5070495431 @default.
- W2138435704 hasAuthorship W2138435704A5079274855 @default.
- W2138435704 hasAuthorship W2138435704A5083189507 @default.
- W2138435704 hasAuthorship W2138435704A5085705153 @default.
- W2138435704 hasAuthorship W2138435704A5090985856 @default.
- W2138435704 hasBestOaLocation W21384357041 @default.