Matches in SemOpenAlex for { <https://semopenalex.org/work/W2138462034> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2138462034 endingPage "924" @default.
- W2138462034 startingPage "919" @default.
- W2138462034 abstract "Prenatal diagnosis in families affected by X-linked recessive disorders should ideally be limited to the subjects at increased risk, i.e. male fetuses, in order to avoid the risk of fetal loss due to the invasive procedure in healthy female fetuses. The aim of the study was to assess the fetal sex within the first trimester of gestation by two non-invasive approaches, using ultrasonography and a molecular analysis of fetal DNA extracted from whole maternal blood with specific markers, in order to avoid invasive sampling in female fetuses.A total number of 18 fetuses at risk for an X-linked recessive disease were included in the present investigation. Maternal peripheral blood was analysed between 7 and 12 weeks of gestation by nested PCR for the detection of fetal DNA and the prediction of fetal gender. In addition, when the biparietal diameter (BPD) was between 21 and 23 mm, an ultrasonographic examination was carried out to assess the fetal gender. CVS was then performed in male fetuses only.Fetal gender was correctly assigned by ultrasonography between 21 and 23 mm of BPD in all the cases studied, whereas DNA extracted from whole maternal blood accurately predicted the gender in all the female cases (10), but failed in 4 out of 8 male fetuses, erroneously assigned as females.The present study shows that sonography is able to accurately predict the fetal gender within the first trimester of pregnancy, whereas the molecular analysis of DNA extracted from whole maternal blood is biased by false-Y-negative results in 50% of the cases." @default.
- W2138462034 created "2016-06-24" @default.
- W2138462034 creator A5008003923 @default.
- W2138462034 creator A5035873931 @default.
- W2138462034 creator A5053959687 @default.
- W2138462034 creator A5055488968 @default.
- W2138462034 creator A5074676556 @default.
- W2138462034 creator A5082915486 @default.
- W2138462034 date "2002-01-01" @default.
- W2138462034 modified "2023-09-28" @default.
- W2138462034 title "Non-invasive first trimester fetal gender assignment in pregnancies at risk for X-linked recessive diseases" @default.
- W2138462034 cites W1966478800 @default.
- W2138462034 cites W1992305195 @default.
- W2138462034 cites W2000287561 @default.
- W2138462034 cites W2003130419 @default.
- W2138462034 cites W2015285874 @default.
- W2138462034 cites W2026822536 @default.
- W2138462034 cites W2028115197 @default.
- W2138462034 cites W2030404547 @default.
- W2138462034 cites W2045356522 @default.
- W2138462034 cites W2045440710 @default.
- W2138462034 cites W2046049047 @default.
- W2138462034 cites W2050221951 @default.
- W2138462034 cites W2053593917 @default.
- W2138462034 cites W2066796679 @default.
- W2138462034 cites W2070436641 @default.
- W2138462034 cites W2092479048 @default.
- W2138462034 cites W2100977485 @default.
- W2138462034 cites W2106534605 @default.
- W2138462034 cites W2115865929 @default.
- W2138462034 cites W2117247353 @default.
- W2138462034 cites W2117325612 @default.
- W2138462034 cites W2132158935 @default.
- W2138462034 cites W2145276698 @default.
- W2138462034 cites W2166688382 @default.
- W2138462034 cites W2767847842 @default.
- W2138462034 cites W4243868329 @default.
- W2138462034 cites W4376453726 @default.
- W2138462034 doi "https://doi.org/10.1002/pd.434" @default.
- W2138462034 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12378578" @default.
- W2138462034 hasPublicationYear "2002" @default.
- W2138462034 type Work @default.
- W2138462034 sameAs 2138462034 @default.
- W2138462034 citedByCount "21" @default.
- W2138462034 countsByYear W21384620342012 @default.
- W2138462034 countsByYear W21384620342013 @default.
- W2138462034 countsByYear W21384620342014 @default.
- W2138462034 countsByYear W21384620342015 @default.
- W2138462034 countsByYear W21384620342016 @default.
- W2138462034 crossrefType "journal-article" @default.
- W2138462034 hasAuthorship W2138462034A5008003923 @default.
- W2138462034 hasAuthorship W2138462034A5035873931 @default.
- W2138462034 hasAuthorship W2138462034A5053959687 @default.
- W2138462034 hasAuthorship W2138462034A5055488968 @default.
- W2138462034 hasAuthorship W2138462034A5074676556 @default.
- W2138462034 hasAuthorship W2138462034A5082915486 @default.
- W2138462034 hasConcept C131872663 @default.
- W2138462034 hasConcept C152110520 @default.
- W2138462034 hasConcept C172680121 @default.
- W2138462034 hasConcept C2778258057 @default.
- W2138462034 hasConcept C2779234561 @default.
- W2138462034 hasConcept C29456083 @default.
- W2138462034 hasConcept C46973012 @default.
- W2138462034 hasConcept C54355233 @default.
- W2138462034 hasConcept C71924100 @default.
- W2138462034 hasConcept C86803240 @default.
- W2138462034 hasConceptScore W2138462034C131872663 @default.
- W2138462034 hasConceptScore W2138462034C152110520 @default.
- W2138462034 hasConceptScore W2138462034C172680121 @default.
- W2138462034 hasConceptScore W2138462034C2778258057 @default.
- W2138462034 hasConceptScore W2138462034C2779234561 @default.
- W2138462034 hasConceptScore W2138462034C29456083 @default.
- W2138462034 hasConceptScore W2138462034C46973012 @default.
- W2138462034 hasConceptScore W2138462034C54355233 @default.
- W2138462034 hasConceptScore W2138462034C71924100 @default.
- W2138462034 hasConceptScore W2138462034C86803240 @default.
- W2138462034 hasIssue "10" @default.
- W2138462034 hasLocation W21384620341 @default.
- W2138462034 hasLocation W21384620342 @default.
- W2138462034 hasOpenAccess W2138462034 @default.
- W2138462034 hasPrimaryLocation W21384620341 @default.
- W2138462034 hasRelatedWork W2004082093 @default.
- W2138462034 hasRelatedWork W2056752164 @default.
- W2138462034 hasRelatedWork W2093112264 @default.
- W2138462034 hasRelatedWork W2153600510 @default.
- W2138462034 hasRelatedWork W2163638983 @default.
- W2138462034 hasRelatedWork W2329009029 @default.
- W2138462034 hasRelatedWork W2368136628 @default.
- W2138462034 hasRelatedWork W2400331667 @default.
- W2138462034 hasRelatedWork W28170546 @default.
- W2138462034 hasRelatedWork W2309276520 @default.
- W2138462034 hasVolume "22" @default.
- W2138462034 isParatext "false" @default.
- W2138462034 isRetracted "false" @default.
- W2138462034 magId "2138462034" @default.
- W2138462034 workType "article" @default.