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- W2138504916 abstract "“Therapeutic angiogenesis” describes an emerging field of cardiovascular medicine whereby new blood vessels are induced to grow to supply oxygen and nutrients to ischemic cardiac or skeletal muscle. Various methods of producing therapeutic angiogenesis have been employed, including mechanical means, gene therapy, and the use of growth factors, among others. The use of appropriate large-animal models is essential if these therapies are to be critically evaluated in a preclinical setting before their use in humans, yet little has been written comparing the various available models. Over the past decade, swine have been increasingly used in studies of chronic ischemia because of their numerous similarities to humans, including minimal preexisting coronary collaterals as well as similar coronary anatomy and physiology. Consequently, this review describes the most commonly used swine models of chronic myocardial ischemia with special attention to regional myocardial blood flow and function and critically evaluates the strengths and weaknesses of each model in terms of utility for preclinical trials of angiogenic therapies." @default.
- W2138504916 created "2016-06-24" @default.
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- W2138504916 date "2003-05-01" @default.
- W2138504916 modified "2023-10-16" @default.
- W2138504916 title "Translational Physiology: Porcine models of human coronary artery disease: implications for preclinical trials of therapeutic angiogenesis" @default.
- W2138504916 cites W1552492209 @default.
- W2138504916 cites W1805604397 @default.
- W2138504916 cites W1964248463 @default.
- W2138504916 cites W1964523691 @default.
- W2138504916 cites W1969258395 @default.
- W2138504916 cites W1970299243 @default.
- W2138504916 cites W1972790834 @default.
- W2138504916 cites W1972795061 @default.
- W2138504916 cites W1973718403 @default.
- W2138504916 cites W1983700583 @default.
- W2138504916 cites W1983897769 @default.
- W2138504916 cites W1985112972 @default.
- W2138504916 cites W1986630616 @default.
- W2138504916 cites W1989997373 @default.
- W2138504916 cites W1990763881 @default.
- W2138504916 cites W1998710689 @default.
- W2138504916 cites W2000600255 @default.
- W2138504916 cites W2002526689 @default.
- W2138504916 cites W2008305464 @default.
- W2138504916 cites W2011896478 @default.
- W2138504916 cites W2012258665 @default.
- W2138504916 cites W2015220059 @default.
- W2138504916 cites W2016616111 @default.
- W2138504916 cites W2022457827 @default.
- W2138504916 cites W2027596785 @default.
- W2138504916 cites W2028456433 @default.
- W2138504916 cites W2031154528 @default.
- W2138504916 cites W2031435841 @default.
- W2138504916 cites W2032493010 @default.
- W2138504916 cites W2037956020 @default.
- W2138504916 cites W2046004615 @default.
- W2138504916 cites W2047399325 @default.
- W2138504916 cites W2050499474 @default.
- W2138504916 cites W2051987769 @default.
- W2138504916 cites W2053704719 @default.
- W2138504916 cites W2056148198 @default.
- W2138504916 cites W2056428937 @default.
- W2138504916 cites W2058661116 @default.
- W2138504916 cites W2065780418 @default.
- W2138504916 cites W2066037166 @default.
- W2138504916 cites W2068672205 @default.
- W2138504916 cites W2070276084 @default.
- W2138504916 cites W2070364693 @default.
- W2138504916 cites W2074758042 @default.
- W2138504916 cites W2078264709 @default.
- W2138504916 cites W2078525879 @default.
- W2138504916 cites W2081376090 @default.
- W2138504916 cites W2083922905 @default.
- W2138504916 cites W2085738449 @default.
- W2138504916 cites W2089548096 @default.
- W2138504916 cites W2090415566 @default.
- W2138504916 cites W2093457985 @default.
- W2138504916 cites W2093733373 @default.
- W2138504916 cites W2094216675 @default.
- W2138504916 cites W2099868396 @default.
- W2138504916 cites W2100101755 @default.
- W2138504916 cites W2103317708 @default.
- W2138504916 cites W2105218032 @default.
- W2138504916 cites W2105772199 @default.
- W2138504916 cites W2110766488 @default.
- W2138504916 cites W2122689055 @default.
- W2138504916 cites W2130999104 @default.
- W2138504916 cites W2133025198 @default.
- W2138504916 cites W2133592793 @default.
- W2138504916 cites W2137366510 @default.
- W2138504916 cites W2140003426 @default.
- W2138504916 cites W2145639716 @default.
- W2138504916 cites W2146564676 @default.
- W2138504916 cites W2150884552 @default.
- W2138504916 cites W2162205976 @default.
- W2138504916 cites W2168161582 @default.
- W2138504916 cites W2169251908 @default.
- W2138504916 cites W2280529542 @default.
- W2138504916 cites W2281494855 @default.
- W2138504916 cites W2347185577 @default.
- W2138504916 cites W2396719112 @default.
- W2138504916 cites W94974053 @default.
- W2138504916 cites W96403324 @default.
- W2138504916 doi "https://doi.org/10.1152/japplphysiol.00465.2002" @default.
- W2138504916 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12679343" @default.
- W2138504916 hasPublicationYear "2003" @default.
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