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• W2138566998 abstract "d-Galacturonic acid is a major component of pectins but cannot be metabolized by Saccharomyces cerevisiae. It is assumed not to be taken up. We show that yeast displays surprisingly rapid low-affinity uptake of d-galacturonic acid, strongly increasing with decreasing extracellular pH and without saturation up to 1.5 M. There was no intracellular concentration above the extracellular level and transport was reversible. Among more than 160 single and multiple deletion mutants in channels and transporters, no strain was affected in d-galacturonic acid uptake. The uptake was not inhibited by any compound tested as candidate competitive inhibitor, including d-glucuronic acid, which was also transported. The characteristics of d-galacturonic acid uptake are consistent with involvement of a channel-type system, probably encoded by multiple genes." @default.
• W2138566998 created "2016-06-24" @default.
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• W2138566998 date "2012-06-19" @default.
• W2138566998 modified "2023-09-23" @default.
• W2138566998 title "Evidence for rapid uptake of<scp>d</scp>-galacturonic acid in the yeast<i>Saccharomyces cerevisiae</i>by a channel-type transport system" @default.
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• W2138566998 doi "https://doi.org/10.1016/j.febslet.2012.06.012" @default.
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