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- W2138642022 abstract "IT HAS BEEN DEMONSTRATED that administration of desoxycorticosterone acetate and certain related substances is followed by potassium diuresis and diminished urinary excretion of Na and Cl in normal and in adrenalectomized animals (i). The mechanism of production of this phenomenon is not clearly understood, but it appears to be dependent, in part at least, upon a primary effect on the kidney. The present investigation was undertaken for the purpose of ascertaining whether evidence of an extrarenal effect upon the distribution of electrolytes could be demonstrated. The intraperitoneal glucose technic of Schechter and his associates (2) was employed for the purpose of studying the possible influence of desoxycorticosterone acetate and progesterone upon the rate of passage ofNa and Cl into the artificial peritoneal fluid. Normal, unanesthetised dogs (10 to 15 kg.) were used in all cases. The fluid introduced into the peritoneum was 5.5% dextrose in distilled water, 100 cc. per kg." @default.
- W2138642022 created "2016-06-24" @default.
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- W2138642022 date "1940-10-01" @default.
- W2138642022 modified "2023-09-27" @default.
- W2138642022 title "INFLUENCE OF DESOXYCORTICOSTERONE ACETATE AND OF PROGESTERONE ON THE DIFFUSION OF SODIUM AND CHLORIDE INTO THE PERITONEAL SPACE1" @default.
- W2138642022 doi "https://doi.org/10.1210/endo-27-4-652" @default.
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