Matches in SemOpenAlex for { <https://semopenalex.org/work/W2138672810> ?p ?o ?g. }
- W2138672810 endingPage "74" @default.
- W2138672810 startingPage "58" @default.
- W2138672810 abstract "Prior to the 1970s, severe cases of antineutrophil cytoplasmic antibody associated vasculitis (AAV) were thought to be invariably fatal. However, the use of cyclophosphamide-based treatment regimens fundamentally altered disease outcomes, transforming AAV into a manageable, chronic illness. Despite the tremendous success of cyclophosphamide in the treatment of AAV, there remained a need for alternative therapies, due to high rates of treatment failures and significant toxicities. In recent years, with the introduction of targeted biologic response modifiers into clinical practice, many have hoped that the treatment options for AAV could be expanded. Rituximab, a chimeric monoclonal antibody directed against the B-lymphocyte protein CD20, has been the most successful biologic response modifier to be used in AAV. Following the first report of its use in AAV in 2001, experience with rituximab for treatment of AAV has rapidly expanded. Rituximab, in combination with glucocorticosteroids, is now well established as a safe and effective alternative to cyclophosphamide for remission induction for severe manifestations of granulomatosis with polyangiitis and microscopic polyangiitis. In addition, initial experiences with rituximab for remission maintenance in these diseases have been favorable, as have experiences for remission induction in eosinophilic granulomatosis with polyangiitis." @default.
- W2138672810 created "2016-06-24" @default.
- W2138672810 creator A5012967877 @default.
- W2138672810 creator A5046221638 @default.
- W2138672810 creator A5073207965 @default.
- W2138672810 creator A5081992519 @default.
- W2138672810 date "2013-12-17" @default.
- W2138672810 modified "2023-09-26" @default.
- W2138672810 title "Experience with rituximab in the treatment of antineutrophil cytoplasmic antibody associated vasculitis" @default.
- W2138672810 cites W1531848308 @default.
- W2138672810 cites W159968576 @default.
- W2138672810 cites W1914343637 @default.
- W2138672810 cites W1964913193 @default.
- W2138672810 cites W1965622113 @default.
- W2138672810 cites W1966062801 @default.
- W2138672810 cites W1967301441 @default.
- W2138672810 cites W1969368168 @default.
- W2138672810 cites W1972895671 @default.
- W2138672810 cites W198005701 @default.
- W2138672810 cites W1981535363 @default.
- W2138672810 cites W1981683920 @default.
- W2138672810 cites W1982860902 @default.
- W2138672810 cites W1982861220 @default.
- W2138672810 cites W1983339176 @default.
- W2138672810 cites W1984702041 @default.
- W2138672810 cites W1990393482 @default.
- W2138672810 cites W1991541222 @default.
- W2138672810 cites W1992270926 @default.
- W2138672810 cites W1994905941 @default.
- W2138672810 cites W1997620292 @default.
- W2138672810 cites W1997786943 @default.
- W2138672810 cites W1999520120 @default.
- W2138672810 cites W2006128121 @default.
- W2138672810 cites W2007778318 @default.
- W2138672810 cites W2011309580 @default.
- W2138672810 cites W2011557149 @default.
- W2138672810 cites W2014437885 @default.
- W2138672810 cites W2018459774 @default.
- W2138672810 cites W2023473273 @default.
- W2138672810 cites W2024644107 @default.
- W2138672810 cites W2024930078 @default.
- W2138672810 cites W2031517139 @default.
- W2138672810 cites W2031518856 @default.
- W2138672810 cites W2032423298 @default.
- W2138672810 cites W2037162457 @default.
- W2138672810 cites W2038766585 @default.
- W2138672810 cites W2041237232 @default.
- W2138672810 cites W2041729935 @default.
- W2138672810 cites W2046059252 @default.
- W2138672810 cites W2049831025 @default.
- W2138672810 cites W2051055769 @default.
- W2138672810 cites W2053683902 @default.
- W2138672810 cites W2057194530 @default.
- W2138672810 cites W2057490818 @default.
- W2138672810 cites W2058416888 @default.
- W2138672810 cites W2058445558 @default.
- W2138672810 cites W2059227619 @default.
- W2138672810 cites W2060043192 @default.
- W2138672810 cites W2060574301 @default.
- W2138672810 cites W2060774058 @default.
- W2138672810 cites W2062059206 @default.
- W2138672810 cites W2063340779 @default.
- W2138672810 cites W2063470653 @default.
- W2138672810 cites W2064589687 @default.
- W2138672810 cites W2069952390 @default.
- W2138672810 cites W2071782320 @default.
- W2138672810 cites W2077158310 @default.
- W2138672810 cites W2079756029 @default.
- W2138672810 cites W2080428274 @default.
- W2138672810 cites W2080663859 @default.
- W2138672810 cites W2081604198 @default.
- W2138672810 cites W2083324079 @default.
- W2138672810 cites W2084056567 @default.
- W2138672810 cites W2084547554 @default.
- W2138672810 cites W2089016290 @default.
- W2138672810 cites W2093653074 @default.
- W2138672810 cites W2100468967 @default.
- W2138672810 cites W2100809783 @default.
- W2138672810 cites W2102133319 @default.
- W2138672810 cites W2103749236 @default.
- W2138672810 cites W2107598909 @default.
- W2138672810 cites W2108556253 @default.
- W2138672810 cites W2109207289 @default.
- W2138672810 cites W2111928792 @default.
- W2138672810 cites W2114360739 @default.
- W2138672810 cites W2118559127 @default.
- W2138672810 cites W2118994799 @default.
- W2138672810 cites W2122581834 @default.
- W2138672810 cites W2123602110 @default.
- W2138672810 cites W2124208349 @default.
- W2138672810 cites W2126169144 @default.
- W2138672810 cites W2126960177 @default.
- W2138672810 cites W2127258004 @default.
- W2138672810 cites W2129862573 @default.
- W2138672810 cites W2139747034 @default.
- W2138672810 cites W2140515181 @default.
- W2138672810 cites W2142627411 @default.
- W2138672810 cites W2143800846 @default.