Matches in SemOpenAlex for { <https://semopenalex.org/work/W213868782> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W213868782 endingPage "318" @default.
- W213868782 startingPage "316" @default.
- W213868782 abstract "Legumes are involved in IgE mediated food allergy in many countries. Avoidance of allergenic food is the only way to avoid symptomatic reaction. The present study investigated the effect of enzymatic hydrolysis on the allergenicity of three legumes – kidney bean (Phaseolus vulgaris), black gram (Vigna mungo) and peanut (Arachis hypogaea). Soluble protein extracts of the study legumes were sequentially treated by Alcalase® and Flavourzyme®. Allergenicity of hydrolysates was then determined by ELISA, immunoblot, stripped basophil histamine release and skin prick test (SPT). Hydrolysis resulted in the loss of all IgE binding fractions determined by immunoblot in the three legumes. Specific IgE binding in ELISA was reduced by 62.2 ± 7.7%, 87.1 ± 9.6% and 91.8 ± 7.2% in the hydrolysates of kidney bean, black gram and peanut, respectively (p < 0.01). The release of histamine was decreased significantly when sensitized basophils were challenged with hydrolysates as compared to raw extracts. Significant reduction in the biopotency of hydrolysates was also observed in SPT where only 1/10 kidney bean-sensitive individuals, 2/6 black gram-sensitive individuals and 1/7 peanut-sensitive individuals were found positive to their respective hydrolysates. In conclusion, enzymatic hydrolysis is effective in attenuating allergenicity of legume proteins and may be employed for preparing hypoallergenic food extracts." @default.
- W213868782 created "2016-06-24" @default.
- W213868782 creator A5019200929 @default.
- W213868782 creator A5040262998 @default.
- W213868782 creator A5068503435 @default.
- W213868782 date "1962-04-01" @default.
- W213868782 modified "2023-10-15" @default.
- W213868782 title "Studies on the structure of feather keratin" @default.
- W213868782 cites W1628379248 @default.
- W213868782 cites W1678995861 @default.
- W213868782 cites W1796222680 @default.
- W213868782 cites W1984246765 @default.
- W213868782 cites W1995749280 @default.
- W213868782 cites W2007500768 @default.
- W213868782 cites W2007837991 @default.
- W213868782 cites W2052708338 @default.
- W213868782 cites W2072178442 @default.
- W213868782 cites W2096066722 @default.
- W213868782 cites W2319360322 @default.
- W213868782 doi "https://doi.org/10.1016/s0022-2836(62)80010-2" @default.
- W213868782 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14006362" @default.
- W213868782 hasPublicationYear "1962" @default.
- W213868782 type Work @default.
- W213868782 sameAs 213868782 @default.
- W213868782 citedByCount "8" @default.
- W213868782 crossrefType "journal-article" @default.
- W213868782 hasAuthorship W213868782A5019200929 @default.
- W213868782 hasAuthorship W213868782A5040262998 @default.
- W213868782 hasAuthorship W213868782A5068503435 @default.
- W213868782 hasConcept C1122143 @default.
- W213868782 hasConcept C134018914 @default.
- W213868782 hasConcept C141105273 @default.
- W213868782 hasConcept C159654299 @default.
- W213868782 hasConcept C161369605 @default.
- W213868782 hasConcept C185592680 @default.
- W213868782 hasConcept C203014093 @default.
- W213868782 hasConcept C207480886 @default.
- W213868782 hasConcept C2776027960 @default.
- W213868782 hasConcept C2776286235 @default.
- W213868782 hasConcept C2776632002 @default.
- W213868782 hasConcept C2779862049 @default.
- W213868782 hasConcept C2780510475 @default.
- W213868782 hasConcept C2780717550 @default.
- W213868782 hasConcept C28800991 @default.
- W213868782 hasConcept C2910801743 @default.
- W213868782 hasConcept C31903555 @default.
- W213868782 hasConcept C523546767 @default.
- W213868782 hasConcept C53270655 @default.
- W213868782 hasConcept C54355233 @default.
- W213868782 hasConcept C55493867 @default.
- W213868782 hasConcept C59822182 @default.
- W213868782 hasConcept C86803240 @default.
- W213868782 hasConcept C94412978 @default.
- W213868782 hasConceptScore W213868782C1122143 @default.
- W213868782 hasConceptScore W213868782C134018914 @default.
- W213868782 hasConceptScore W213868782C141105273 @default.
- W213868782 hasConceptScore W213868782C159654299 @default.
- W213868782 hasConceptScore W213868782C161369605 @default.
- W213868782 hasConceptScore W213868782C185592680 @default.
- W213868782 hasConceptScore W213868782C203014093 @default.
- W213868782 hasConceptScore W213868782C207480886 @default.
- W213868782 hasConceptScore W213868782C2776027960 @default.
- W213868782 hasConceptScore W213868782C2776286235 @default.
- W213868782 hasConceptScore W213868782C2776632002 @default.
- W213868782 hasConceptScore W213868782C2779862049 @default.
- W213868782 hasConceptScore W213868782C2780510475 @default.
- W213868782 hasConceptScore W213868782C2780717550 @default.
- W213868782 hasConceptScore W213868782C28800991 @default.
- W213868782 hasConceptScore W213868782C2910801743 @default.
- W213868782 hasConceptScore W213868782C31903555 @default.
- W213868782 hasConceptScore W213868782C523546767 @default.
- W213868782 hasConceptScore W213868782C53270655 @default.
- W213868782 hasConceptScore W213868782C54355233 @default.
- W213868782 hasConceptScore W213868782C55493867 @default.
- W213868782 hasConceptScore W213868782C59822182 @default.
- W213868782 hasConceptScore W213868782C86803240 @default.
- W213868782 hasConceptScore W213868782C94412978 @default.
- W213868782 hasIssue "4" @default.
- W213868782 hasLocation W2138687821 @default.
- W213868782 hasLocation W2138687822 @default.
- W213868782 hasOpenAccess W213868782 @default.
- W213868782 hasPrimaryLocation W2138687821 @default.
- W213868782 hasRelatedWork W1572475986 @default.
- W213868782 hasRelatedWork W1987313305 @default.
- W213868782 hasRelatedWork W2009834435 @default.
- W213868782 hasRelatedWork W2245045968 @default.
- W213868782 hasRelatedWork W231149005 @default.
- W213868782 hasRelatedWork W2334729281 @default.
- W213868782 hasRelatedWork W2612612536 @default.
- W213868782 hasRelatedWork W2741683623 @default.
- W213868782 hasRelatedWork W4205287286 @default.
- W213868782 hasRelatedWork W5118140 @default.
- W213868782 hasVolume "4" @default.
- W213868782 isParatext "false" @default.
- W213868782 isRetracted "false" @default.
- W213868782 magId "213868782" @default.
- W213868782 workType "article" @default.