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- W2138746516 abstract "We present a disposable nano-grating SPR (Surface Plasmon Resonance) sensor chip for the detection of biomolecule concentration. The sensor chip has two fluidic channels, each encapsulating a nano-scale grating for SPR sensing. Compared to the previous multi-channel SPR sensors using fiber-optic switches or special prisms, the present SPR sensor chip achieves a compact and inexpensive SPR sensor using an external mirror. For disposable SPR sensors, the fluidic channels with nano- gratings were fabricated by micromolding process. We successfully measured the binding reaction rate for the 2nM ~ 200nM m-antibiotin, thus verifying biomolecule concentration detectability of the nano-grating SPR sensor chip. In addition, the binding reaction rates measured from the present SPR sensor chip agreed well with those from a commercialized SPR sensor. Therefore, the present nano-grating SPR sensor chip offers simple structure and low cost for use in integrated lab-on-a-chip and point-of-care services." @default.
- W2138746516 created "2016-06-24" @default.
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- W2138746516 date "2008-01-01" @default.
- W2138746516 modified "2023-10-16" @default.
- W2138746516 title "A disposable nano grating SPR sensor chip for detection of biomolecule concentration" @default.
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- W2138746516 doi "https://doi.org/10.1109/nems.2008.4484485" @default.
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