FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2138755686> ?p ?o ?g. }

• W2138755686 endingPage "213" @default.
• W2138755686 startingPage "204" @default.
• W2138755686 abstract "We have cloned the rat homologue of the ring-H2 protein Goliath involved in Drosophila development. The rat Goliath mRNA (1.85 kb) was translated as a major ubiquitous protein species of 28-kDa and three larger isoforms (50, 46, and 36 kDa) expressed mainly in liver, lung, stomach, heart, and thymus and barely detectable in other tissues (kidney, skeletal muscle, brain, testis, intestine, and spleen). By immunohistochemistry on rat testis sections, we localized the protein in interstitial tissue and seminiferous tubules. In tubules, Goliath was expressed mainly in postmeiotic germ cells and to a much lesser extent in Sertoli cells. In the interstitium, Goliath was exclusively present in Leydig cells. Using a series of immunolabeling, cellular fractionation, and electron microscopy experiments, we established that Goliath is present in mitochondria of the R2C Leydig cell line. Using short-term hypophysectomized animals, we showed that Goliath is regulated by LH/hCG in Leydig cells but not in germ cells. This regulation in Leydig cells concerned only the 50-kDa isoform. This report is the first description of a differential regulation of the Goliath protein between germ cells and Leydig cells." @default.
• W2138755686 created "2016-06-24" @default.
• W2138755686 creator A5016279870 @default.
• W2138755686 creator A5033862156 @default.
• W2138755686 creator A5059084738 @default.
• W2138755686 creator A5073969996 @default.
• W2138755686 creator A5089993154 @default.
• W2138755686 date "2004-01-01" @default.
• W2138755686 modified "2023-10-02" @default.
• W2138755686 title "Goliath, a Ring-H2 Mitochondrial Protein, Regulated by Luteinizing Hormone/Human Chorionic Gonadotropin in Rat Leydig Cells1" @default.
• W2138755686 cites W1017389710 @default.
• W2138755686 cites W1493663903 @default.
• W2138755686 cites W1869254767 @default.
• W2138755686 cites W1964547619 @default.
• W2138755686 cites W1974685280 @default.
• W2138755686 cites W1975284044 @default.
• W2138755686 cites W1990409602 @default.
• W2138755686 cites W1993211404 @default.
• W2138755686 cites W1998681868 @default.
• W2138755686 cites W2002821147 @default.
• W2138755686 cites W2004685080 @default.
• W2138755686 cites W2018157254 @default.
• W2138755686 cites W2022615484 @default.
• W2138755686 cites W2026800854 @default.
• W2138755686 cites W2026973137 @default.
• W2138755686 cites W2035081412 @default.
• W2138755686 cites W2039604641 @default.
• W2138755686 cites W2047539110 @default.
• W2138755686 cites W2051448662 @default.
• W2138755686 cites W2053840076 @default.
• W2138755686 cites W2054546670 @default.
• W2138755686 cites W2061236466 @default.
• W2138755686 cites W2065361117 @default.
• W2138755686 cites W2069348185 @default.
• W2138755686 cites W2069473876 @default.
• W2138755686 cites W2071926776 @default.
• W2138755686 cites W2077063665 @default.
• W2138755686 cites W2085257352 @default.
• W2138755686 cites W2086560719 @default.
• W2138755686 cites W2086615330 @default.
• W2138755686 cites W2088320809 @default.
• W2138755686 cites W2097892072 @default.
• W2138755686 cites W2105848552 @default.
• W2138755686 cites W2108944287 @default.
• W2138755686 cites W2117987251 @default.
• W2138755686 cites W2137424160 @default.
• W2138755686 cites W2139315148 @default.
• W2138755686 cites W2152458080 @default.
• W2138755686 cites W2161159096 @default.
• W2138755686 cites W2168968579 @default.
• W2138755686 cites W325216255 @default.
• W2138755686 cites W4250662177 @default.
• W2138755686 doi "https://doi.org/10.1095/biolreprod.103.018820" @default.
• W2138755686 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/13679316" @default.
• W2138755686 hasPublicationYear "2004" @default.
• W2138755686 type Work @default.
• W2138755686 sameAs 2138755686 @default.
• W2138755686 citedByCount "14" @default.
• W2138755686 countsByYear W21387556862012 @default.
• W2138755686 countsByYear W21387556862013 @default.
• W2138755686 countsByYear W21387556862015 @default.
• W2138755686 countsByYear W21387556862016 @default.
• W2138755686 countsByYear W21387556862018 @default.
• W2138755686 countsByYear W21387556862020 @default.
• W2138755686 countsByYear W21387556862023 @default.
• W2138755686 crossrefType "journal-article" @default.
• W2138755686 hasAuthorship W2138755686A5016279870 @default.
• W2138755686 hasAuthorship W2138755686A5033862156 @default.
• W2138755686 hasAuthorship W2138755686A5059084738 @default.
• W2138755686 hasAuthorship W2138755686A5073969996 @default.
• W2138755686 hasAuthorship W2138755686A5089993154 @default.
• W2138755686 hasConcept C104317684 @default.
• W2138755686 hasConcept C123765429 @default.
• W2138755686 hasConcept C126322002 @default.
• W2138755686 hasConcept C134018914 @default.
• W2138755686 hasConcept C2777736315 @default.
• W2138755686 hasConcept C2778054371 @default.
• W2138755686 hasConcept C2778575703 @default.
• W2138755686 hasConcept C2779066085 @default.
• W2138755686 hasConcept C2779122487 @default.
• W2138755686 hasConcept C2781068068 @default.
• W2138755686 hasConcept C54355233 @default.
• W2138755686 hasConcept C71315377 @default.
• W2138755686 hasConcept C71924100 @default.
• W2138755686 hasConcept C86803240 @default.
• W2138755686 hasConcept C95444343 @default.
• W2138755686 hasConceptScore W2138755686C104317684 @default.
• W2138755686 hasConceptScore W2138755686C123765429 @default.
• W2138755686 hasConceptScore W2138755686C126322002 @default.
• W2138755686 hasConceptScore W2138755686C134018914 @default.
• W2138755686 hasConceptScore W2138755686C2777736315 @default.
• W2138755686 hasConceptScore W2138755686C2778054371 @default.
• W2138755686 hasConceptScore W2138755686C2778575703 @default.
• W2138755686 hasConceptScore W2138755686C2779066085 @default.
• W2138755686 hasConceptScore W2138755686C2779122487 @default.
• W2138755686 hasConceptScore W2138755686C2781068068 @default.
• W2138755686 hasConceptScore W2138755686C54355233 @default.
• W2138755686 hasConceptScore W2138755686C71315377 @default.

• next