Matches in SemOpenAlex for { <https://semopenalex.org/work/W2138816624> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2138816624 abstract "Abstract The role of the endothelium and vascular tone was studied on histamine-induced relaxation and contraction of the rabbit coeliac artery. Histamine contracted the tissue via the release of noradrenaline (NA), an action blocked by prazosin and mepyramine but not influenced by endothelial removal. Tachyphylaxis readily developed to histamine-induced contractions. After a moderate tone (40–55%) was induced with NA, histamine relaxed the tissues concentration-dependently. This relaxation was absent when the endothelium was removed indicating that the receptors involved are located on the endothelium. When the tone was increased to 80–85% with NA, relaxation could only be demonstrated after blocking H1-receptors. Removal of the endothelium did not influence this response. The relaxant effect of histamine in both preparations, however, was blocked by metiamide indicating that it is H2-receptor mediated. In the rabbit coeliac artery, endothelial H2-receptors are readily activated at moderate tone while muscular H2-receptors are stimulated at high tone after blocking H1-receptors. The predominance of H2-receptors in this artery may serve the physiological function of vasodilation in the blood vessels of the stomach." @default.
- W2138816624 created "2016-06-24" @default.
- W2138816624 creator A5078313315 @default.
- W2138816624 date "1991-06-01" @default.
- W2138816624 modified "2023-09-25" @default.
- W2138816624 title "Role of the Endothelium and Smooth Muscle Tone in the Dilator Response of the Rabbit Coeliac Artery to Histamine" @default.
- W2138816624 cites W1844412926 @default.
- W2138816624 cites W1976145582 @default.
- W2138816624 cites W1987245561 @default.
- W2138816624 cites W2002885182 @default.
- W2138816624 cites W2003397006 @default.
- W2138816624 cites W2007400729 @default.
- W2138816624 cites W2007905143 @default.
- W2138816624 cites W2030326209 @default.
- W2138816624 cites W2045612450 @default.
- W2138816624 cites W2049072541 @default.
- W2138816624 cites W2067444275 @default.
- W2138816624 cites W2091692613 @default.
- W2138816624 cites W2094504964 @default.
- W2138816624 cites W2129367506 @default.
- W2138816624 doi "https://doi.org/10.1111/j.2042-7158.1991.tb03496.x" @default.
- W2138816624 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1681051" @default.
- W2138816624 hasPublicationYear "1991" @default.
- W2138816624 type Work @default.
- W2138816624 sameAs 2138816624 @default.
- W2138816624 citedByCount "9" @default.
- W2138816624 crossrefType "journal-article" @default.
- W2138816624 hasAuthorship W2138816624A5078313315 @default.
- W2138816624 hasConcept C1122143 @default.
- W2138816624 hasConcept C120770815 @default.
- W2138816624 hasConcept C126322002 @default.
- W2138816624 hasConcept C134018914 @default.
- W2138816624 hasConcept C159545944 @default.
- W2138816624 hasConcept C168481208 @default.
- W2138816624 hasConcept C170493617 @default.
- W2138816624 hasConcept C185592680 @default.
- W2138816624 hasConcept C2776885963 @default.
- W2138816624 hasConcept C2776992346 @default.
- W2138816624 hasConcept C2777032099 @default.
- W2138816624 hasConcept C2779090179 @default.
- W2138816624 hasConcept C2779624279 @default.
- W2138816624 hasConcept C34400551 @default.
- W2138816624 hasConcept C71924100 @default.
- W2138816624 hasConceptScore W2138816624C1122143 @default.
- W2138816624 hasConceptScore W2138816624C120770815 @default.
- W2138816624 hasConceptScore W2138816624C126322002 @default.
- W2138816624 hasConceptScore W2138816624C134018914 @default.
- W2138816624 hasConceptScore W2138816624C159545944 @default.
- W2138816624 hasConceptScore W2138816624C168481208 @default.
- W2138816624 hasConceptScore W2138816624C170493617 @default.
- W2138816624 hasConceptScore W2138816624C185592680 @default.
- W2138816624 hasConceptScore W2138816624C2776885963 @default.
- W2138816624 hasConceptScore W2138816624C2776992346 @default.
- W2138816624 hasConceptScore W2138816624C2777032099 @default.
- W2138816624 hasConceptScore W2138816624C2779090179 @default.
- W2138816624 hasConceptScore W2138816624C2779624279 @default.
- W2138816624 hasConceptScore W2138816624C34400551 @default.
- W2138816624 hasConceptScore W2138816624C71924100 @default.
- W2138816624 hasLocation W21388166241 @default.
- W2138816624 hasLocation W21388166242 @default.
- W2138816624 hasOpenAccess W2138816624 @default.
- W2138816624 hasPrimaryLocation W21388166241 @default.
- W2138816624 hasRelatedWork W1963494675 @default.
- W2138816624 hasRelatedWork W1997038447 @default.
- W2138816624 hasRelatedWork W2005373223 @default.
- W2138816624 hasRelatedWork W2048222429 @default.
- W2138816624 hasRelatedWork W2094504964 @default.
- W2138816624 hasRelatedWork W2138816624 @default.
- W2138816624 hasRelatedWork W2406314348 @default.
- W2138816624 hasRelatedWork W2414147420 @default.
- W2138816624 hasRelatedWork W2415301784 @default.
- W2138816624 hasRelatedWork W2442293311 @default.
- W2138816624 isParatext "false" @default.
- W2138816624 isRetracted "false" @default.
- W2138816624 magId "2138816624" @default.
- W2138816624 workType "article" @default.