Matches in SemOpenAlex for { <https://semopenalex.org/work/W2138819914> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2138819914 endingPage "995" @default.
- W2138819914 startingPage "992" @default.
- W2138819914 abstract "This study was designed to assess the relative antiarrhythmic activity of fixed doses of 2 beta-adrenergic blocking agents, propranolol and acebutolol, in a prospective double-blind crossover trial. Twenty-one patients who had at least 30 premature ventricular contractions (PVCs) per hour while receiving placebo were entered into the study. Ten patients were randomized to initially receive propranolol, 40 mg every 8 hours, and 11 were assigned to receive acebutolol, 300 mg every 8 hours. After 6 weeks of treatment, patients were weaned off medication for 1 week and then placed on placebo for 1 week. Eighteen patients were available and eligible for crossover to the alternative regimen for an additional 6 weeks. All 21 patients completed courses with propranolol and 17 completed courses with acebutolol. The mean number of PVCs per hour during placebo, propranolol and acebutolol treatment were 267, 87 and 119, respectively. Using paired t test statistics on observation differences, both propranolol and acebutolol significantly reduced the number of PVCs per hour compared with placebo, whereas similar analysis revealed no significant difference in the antiarrhythmic effect. However, with the current sample size the power of the test is too low for the latter conclusion to be stated with confidence. Side effects were mild and infrequent, requiring discontinuation of acebutolol in 2 patients and discontinuation of propranolol in 1. Thus, acebutolol is a safe and effective antiarrhythmic agent and compares favorably with propranolol." @default.
- W2138819914 created "2016-06-24" @default.
- W2138819914 creator A5012896101 @default.
- W2138819914 creator A5045082485 @default.
- W2138819914 creator A5060928089 @default.
- W2138819914 date "1983-11-01" @default.
- W2138819914 modified "2023-10-18" @default.
- W2138819914 title "Comparison of the antiarrhythmic effects of acebutolol and propranolol in the treatment of ventricular arrhythmias" @default.
- W2138819914 cites W1981112006 @default.
- W2138819914 cites W1982816931 @default.
- W2138819914 cites W1998900810 @default.
- W2138819914 cites W2011302231 @default.
- W2138819914 cites W2012912593 @default.
- W2138819914 cites W2018711737 @default.
- W2138819914 cites W2036697769 @default.
- W2138819914 cites W2057443384 @default.
- W2138819914 cites W2059878231 @default.
- W2138819914 cites W2060271936 @default.
- W2138819914 cites W2060272889 @default.
- W2138819914 cites W2068019008 @default.
- W2138819914 cites W2075020711 @default.
- W2138819914 cites W2091247697 @default.
- W2138819914 cites W2101685117 @default.
- W2138819914 cites W2102259200 @default.
- W2138819914 cites W2396072514 @default.
- W2138819914 doi "https://doi.org/10.1016/0002-9149(83)90518-0" @default.
- W2138819914 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6195911" @default.
- W2138819914 hasPublicationYear "1983" @default.
- W2138819914 type Work @default.
- W2138819914 sameAs 2138819914 @default.
- W2138819914 citedByCount "8" @default.
- W2138819914 crossrefType "journal-article" @default.
- W2138819914 hasAuthorship W2138819914A5012896101 @default.
- W2138819914 hasAuthorship W2138819914A5045082485 @default.
- W2138819914 hasAuthorship W2138819914A5060928089 @default.
- W2138819914 hasConcept C126322002 @default.
- W2138819914 hasConcept C142724271 @default.
- W2138819914 hasConcept C164705383 @default.
- W2138819914 hasConcept C204787440 @default.
- W2138819914 hasConcept C27081682 @default.
- W2138819914 hasConcept C2778131192 @default.
- W2138819914 hasConcept C2778151854 @default.
- W2138819914 hasConcept C2778198053 @default.
- W2138819914 hasConcept C2778679995 @default.
- W2138819914 hasConcept C2778715236 @default.
- W2138819914 hasConcept C2778742482 @default.
- W2138819914 hasConcept C2780074459 @default.
- W2138819914 hasConcept C2781413609 @default.
- W2138819914 hasConcept C42219234 @default.
- W2138819914 hasConcept C44249647 @default.
- W2138819914 hasConcept C71924100 @default.
- W2138819914 hasConcept C87813604 @default.
- W2138819914 hasConceptScore W2138819914C126322002 @default.
- W2138819914 hasConceptScore W2138819914C142724271 @default.
- W2138819914 hasConceptScore W2138819914C164705383 @default.
- W2138819914 hasConceptScore W2138819914C204787440 @default.
- W2138819914 hasConceptScore W2138819914C27081682 @default.
- W2138819914 hasConceptScore W2138819914C2778131192 @default.
- W2138819914 hasConceptScore W2138819914C2778151854 @default.
- W2138819914 hasConceptScore W2138819914C2778198053 @default.
- W2138819914 hasConceptScore W2138819914C2778679995 @default.
- W2138819914 hasConceptScore W2138819914C2778715236 @default.
- W2138819914 hasConceptScore W2138819914C2778742482 @default.
- W2138819914 hasConceptScore W2138819914C2780074459 @default.
- W2138819914 hasConceptScore W2138819914C2781413609 @default.
- W2138819914 hasConceptScore W2138819914C42219234 @default.
- W2138819914 hasConceptScore W2138819914C44249647 @default.
- W2138819914 hasConceptScore W2138819914C71924100 @default.
- W2138819914 hasConceptScore W2138819914C87813604 @default.
- W2138819914 hasIssue "8" @default.
- W2138819914 hasLocation W21388199141 @default.
- W2138819914 hasLocation W21388199142 @default.
- W2138819914 hasOpenAccess W2138819914 @default.
- W2138819914 hasPrimaryLocation W21388199141 @default.
- W2138819914 hasRelatedWork W1990558380 @default.
- W2138819914 hasRelatedWork W1996472379 @default.
- W2138819914 hasRelatedWork W2012912593 @default.
- W2138819914 hasRelatedWork W2018626914 @default.
- W2138819914 hasRelatedWork W2023805169 @default.
- W2138819914 hasRelatedWork W2039263708 @default.
- W2138819914 hasRelatedWork W2067333697 @default.
- W2138819914 hasRelatedWork W2092207649 @default.
- W2138819914 hasRelatedWork W2138819914 @default.
- W2138819914 hasRelatedWork W2463113651 @default.
- W2138819914 hasVolume "52" @default.
- W2138819914 isParatext "false" @default.
- W2138819914 isRetracted "false" @default.
- W2138819914 magId "2138819914" @default.
- W2138819914 workType "article" @default.