Matches in SemOpenAlex for { <https://semopenalex.org/work/W2138820453> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2138820453 endingPage "884" @default.
- W2138820453 startingPage "882" @default.
- W2138820453 abstract "Clostridium difficile diarrhoea (CDD) cases treated with intravenous immunoglobulin during a 2 year period were reviewed to determine disease severity and response to treatment.Of 580 CD cytotoxin-positive patients, five received intravenous immunoglobulin because of protracted and/or recurrent CDD (median duration 50 days, range 45-64); two had biopsy- proven pseudomembranous colitis. The five patients received a median three non-CDD antibiotic courses (range 2-8). Indices of CDD severity included hypoalbuminaemia (n = 5, median 27 g/L, range 11-29), marked hypokalaemia (n = 3, range 1.9-2.7 mM), markedly raised peripheral white cell count (n = 3, 18-34 x 10(9) cells/L), abdominal signs (n = 3) and pyrexia (n = 1). The five cases received metronidazole for median 17 days (range 0-63) plus vancomycin for median 14 days (range 10-42) before intravenous immunoglobulin. One also received rifampicin plus vancomycin and one was given Saccharomyces boulardii.Intravenous immunoglobulin was given at a dosage of 300-500 mg/kg (most commonly 400 mg/kg) for one dose (two patients), two doses (two patients) and in one case for six doses. The latter patient died of intractable CDD, three had a good therapeutic response to intravenous immunoglobulin and CDD recurred within 6 weeks in one case. In the three successfully treated cases, CDD resolved within 11 days.Intravenous immunoglobulin is useful for the treatment of intractable and severe CDD. Controlled studies are needed to assess the true value of this and other forms of passive immunotherapy." @default.
- W2138820453 created "2016-06-24" @default.
- W2138820453 creator A5027928189 @default.
- W2138820453 date "2004-03-24" @default.
- W2138820453 modified "2023-10-16" @default.
- W2138820453 title "Descriptive study of intravenous immunoglobulin for the treatment of recurrent Clostridium difficile diarrhoea" @default.
- W2138820453 cites W2006829441 @default.
- W2138820453 cites W2010075812 @default.
- W2138820453 cites W2050174023 @default.
- W2138820453 cites W2061555327 @default.
- W2138820453 cites W2066446836 @default.
- W2138820453 cites W2066447793 @default.
- W2138820453 cites W2108659548 @default.
- W2138820453 cites W2117604887 @default.
- W2138820453 cites W2167766152 @default.
- W2138820453 doi "https://doi.org/10.1093/jac/dkh176" @default.
- W2138820453 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15073160" @default.
- W2138820453 hasPublicationYear "2004" @default.
- W2138820453 type Work @default.
- W2138820453 sameAs 2138820453 @default.
- W2138820453 citedByCount "197" @default.
- W2138820453 countsByYear W21388204532012 @default.
- W2138820453 countsByYear W21388204532013 @default.
- W2138820453 countsByYear W21388204532014 @default.
- W2138820453 countsByYear W21388204532015 @default.
- W2138820453 countsByYear W21388204532016 @default.
- W2138820453 countsByYear W21388204532017 @default.
- W2138820453 countsByYear W21388204532018 @default.
- W2138820453 countsByYear W21388204532019 @default.
- W2138820453 countsByYear W21388204532020 @default.
- W2138820453 countsByYear W21388204532021 @default.
- W2138820453 countsByYear W21388204532022 @default.
- W2138820453 countsByYear W21388204532023 @default.
- W2138820453 crossrefType "journal-article" @default.
- W2138820453 hasAuthorship W2138820453A5027928189 @default.
- W2138820453 hasBestOaLocation W21388204531 @default.
- W2138820453 hasConcept C126322002 @default.
- W2138820453 hasConcept C141071460 @default.
- W2138820453 hasConcept C159654299 @default.
- W2138820453 hasConcept C203014093 @default.
- W2138820453 hasConcept C2777396551 @default.
- W2138820453 hasConcept C2778980435 @default.
- W2138820453 hasConcept C2779102806 @default.
- W2138820453 hasConcept C2779489039 @default.
- W2138820453 hasConcept C2780898057 @default.
- W2138820453 hasConcept C2991793726 @default.
- W2138820453 hasConcept C2994496256 @default.
- W2138820453 hasConcept C501593827 @default.
- W2138820453 hasConcept C523546767 @default.
- W2138820453 hasConcept C54355233 @default.
- W2138820453 hasConcept C71924100 @default.
- W2138820453 hasConcept C86803240 @default.
- W2138820453 hasConcept C89423630 @default.
- W2138820453 hasConcept C90924648 @default.
- W2138820453 hasConceptScore W2138820453C126322002 @default.
- W2138820453 hasConceptScore W2138820453C141071460 @default.
- W2138820453 hasConceptScore W2138820453C159654299 @default.
- W2138820453 hasConceptScore W2138820453C203014093 @default.
- W2138820453 hasConceptScore W2138820453C2777396551 @default.
- W2138820453 hasConceptScore W2138820453C2778980435 @default.
- W2138820453 hasConceptScore W2138820453C2779102806 @default.
- W2138820453 hasConceptScore W2138820453C2779489039 @default.
- W2138820453 hasConceptScore W2138820453C2780898057 @default.
- W2138820453 hasConceptScore W2138820453C2991793726 @default.
- W2138820453 hasConceptScore W2138820453C2994496256 @default.
- W2138820453 hasConceptScore W2138820453C501593827 @default.
- W2138820453 hasConceptScore W2138820453C523546767 @default.
- W2138820453 hasConceptScore W2138820453C54355233 @default.
- W2138820453 hasConceptScore W2138820453C71924100 @default.
- W2138820453 hasConceptScore W2138820453C86803240 @default.
- W2138820453 hasConceptScore W2138820453C89423630 @default.
- W2138820453 hasConceptScore W2138820453C90924648 @default.
- W2138820453 hasIssue "5" @default.
- W2138820453 hasLocation W21388204531 @default.
- W2138820453 hasLocation W21388204532 @default.
- W2138820453 hasOpenAccess W2138820453 @default.
- W2138820453 hasPrimaryLocation W21388204531 @default.
- W2138820453 hasRelatedWork W1599732385 @default.
- W2138820453 hasRelatedWork W1969791292 @default.
- W2138820453 hasRelatedWork W1972019202 @default.
- W2138820453 hasRelatedWork W2012264555 @default.
- W2138820453 hasRelatedWork W2047638409 @default.
- W2138820453 hasRelatedWork W2123831499 @default.
- W2138820453 hasRelatedWork W2393115371 @default.
- W2138820453 hasRelatedWork W2524986154 @default.
- W2138820453 hasRelatedWork W2924219293 @default.
- W2138820453 hasRelatedWork W4254391329 @default.
- W2138820453 hasVolume "53" @default.
- W2138820453 isParatext "false" @default.
- W2138820453 isRetracted "false" @default.
- W2138820453 magId "2138820453" @default.
- W2138820453 workType "article" @default.