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- W2138838750 abstract "Introduction: We report angioedema as a rare presentation leading to a diagnosis of systemic lupus erythematosus (SLE). Clinical Picture: A diagnosis of angioedema was delayed in a patient presenting with limb and facial swelling until she developed acute upper airway compromise. After excluding allergic and hereditary angioedema, acquired angioedema (AAE) was suspected, possibly precipitated by respiratory tract infection. Associated clinical and laboratory features led to a diagnosis of SLE. Treatment: Management proved challenging and included high dose steroids and immunosuppressants. Outcome: The patient responded to treatment and remains in remission without recurrence of the angioedema. Conclusion: AAE occurs due to the acquired deficiency of inhibitor of C1 component of complement (C1 INH). Lymphoproliferative disorders and anti-C1 INH antibodies are well-described associations. However, one should also consider the possibility of SLE. Key words: Complement C1 inactivator proteins, Angioneurotic oedema" @default.
- W2138838750 created "2016-06-24" @default.
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- W2138838750 date "2007-02-15" @default.
- W2138838750 modified "2023-10-02" @default.
- W2138838750 title "Angioedema and Systemic Lupus Erythematosus – A Complementary Association?" @default.
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- W2138838750 doi "https://doi.org/10.47102/annals-acadmedsg.v36n2p142" @default.
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