FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2138869074> ?p ?o ?g. }

• W2138869074 endingPage "527" @default.
• W2138869074 startingPage "520" @default.
• W2138869074 abstract "Colony-stimulating activity (CSA) is essential for in vitro differentiation of bone marrow cells into colonies of granulocytes and mononuclear cells. While blood monocytes and macrophages are a major source of CSA, recent studies have indicated that CSA may be produced by lymphocytes responding to immunologic stimulation. Lymphocytes, purified from spleens and thymuses of mice by glass wool columns, were incubated in CMRL-1066 medium with fetal calf serum in vitro. Lymphocytes from the thumus and spleen released CSA when cultured in vitro, with peak levels of CSA observed after 7 days of incubation. Stimulation of cultures with phytohemagglutinin, concanavalin A, or pokeweed mitogen resulted in a 2-5-fold increase in CSA release, with peak levels of CSA released after 4 days of incubation. Thymus-dependent lymphocytes were responsible for the release of CSA from unstimulated and mitogen-stimulated cultures, since the incubation of these cultures with rabbit anti-mouse T cell sera abolished their ability to release CSA. Anti-mouse B cell sera had no effect on the ability of lymphocyte cultures to release CSA. These studies suggest that thymocytes and thymus-derived lymphocytes can release CSA in vitro and may be responsible for the increase in CSA observed in certain immunologic reactions." @default.
• W2138869074 created "2016-06-24" @default.
• W2138869074 creator A5005644140 @default.
• W2138869074 creator A5086240234 @default.
• W2138869074 date "1975-03-01" @default.
• W2138869074 modified "2023-10-10" @default.
• W2138869074 title "Release of colony-stimulating activity from thymus-derived lymphocytes." @default.
• W2138869074 cites W1524801043 @default.
• W2138869074 cites W1561861405 @default.
• W2138869074 cites W1903962596 @default.
• W2138869074 cites W1963657554 @default.
• W2138869074 cites W1969093385 @default.
• W2138869074 cites W1976528127 @default.
• W2138869074 cites W1984508258 @default.
• W2138869074 cites W1990994815 @default.
• W2138869074 cites W1992509095 @default.
• W2138869074 cites W2002287505 @default.
• W2138869074 cites W2002778129 @default.
• W2138869074 cites W2014706447 @default.
• W2138869074 cites W2048104971 @default.
• W2138869074 cites W2049363076 @default.
• W2138869074 cites W2053089748 @default.
• W2138869074 cites W2054029124 @default.
• W2138869074 cites W2059493401 @default.
• W2138869074 cites W2060260706 @default.
• W2138869074 cites W2063759625 @default.
• W2138869074 cites W2068658853 @default.
• W2138869074 cites W2082476632 @default.
• W2138869074 cites W2084385332 @default.
• W2138869074 cites W2087833469 @default.
• W2138869074 cites W2091198497 @default.
• W2138869074 cites W2162666693 @default.
• W2138869074 cites W2325427664 @default.
• W2138869074 cites W2398317040 @default.
• W2138869074 cites W2398332432 @default.
• W2138869074 cites W2414065500 @default.
• W2138869074 cites W256767045 @default.
• W2138869074 doi "https://doi.org/10.1172/jci107958" @default.
• W2138869074 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/301779" @default.
• W2138869074 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1090636" @default.
• W2138869074 hasPublicationYear "1975" @default.
• W2138869074 type Work @default.
• W2138869074 sameAs 2138869074 @default.
• W2138869074 citedByCount "96" @default.
• W2138869074 countsByYear W21388690742014 @default.
• W2138869074 countsByYear W21388690742017 @default.
• W2138869074 countsByYear W21388690742021 @default.
• W2138869074 crossrefType "journal-article" @default.
• W2138869074 hasAuthorship W2138869074A5005644140 @default.
• W2138869074 hasAuthorship W2138869074A5086240234 @default.
• W2138869074 hasBestOaLocation W21388690741 @default.
• W2138869074 hasConcept C134018914 @default.
• W2138869074 hasConcept C137061746 @default.
• W2138869074 hasConcept C153911025 @default.
• W2138869074 hasConcept C16685009 @default.
• W2138869074 hasConcept C19869320 @default.
• W2138869074 hasConcept C202751555 @default.
• W2138869074 hasConcept C203014093 @default.
• W2138869074 hasConcept C24998067 @default.
• W2138869074 hasConcept C25642318 @default.
• W2138869074 hasConcept C2777761686 @default.
• W2138869074 hasConcept C2780931953 @default.
• W2138869074 hasConcept C2781005381 @default.
• W2138869074 hasConcept C55493867 @default.
• W2138869074 hasConcept C71924100 @default.
• W2138869074 hasConcept C86803240 @default.
• W2138869074 hasConceptScore W2138869074C134018914 @default.
• W2138869074 hasConceptScore W2138869074C137061746 @default.
• W2138869074 hasConceptScore W2138869074C153911025 @default.
• W2138869074 hasConceptScore W2138869074C16685009 @default.
• W2138869074 hasConceptScore W2138869074C19869320 @default.
• W2138869074 hasConceptScore W2138869074C202751555 @default.
• W2138869074 hasConceptScore W2138869074C203014093 @default.
• W2138869074 hasConceptScore W2138869074C24998067 @default.
• W2138869074 hasConceptScore W2138869074C25642318 @default.
• W2138869074 hasConceptScore W2138869074C2777761686 @default.
• W2138869074 hasConceptScore W2138869074C2780931953 @default.
• W2138869074 hasConceptScore W2138869074C2781005381 @default.
• W2138869074 hasConceptScore W2138869074C55493867 @default.
• W2138869074 hasConceptScore W2138869074C71924100 @default.
• W2138869074 hasConceptScore W2138869074C86803240 @default.
• W2138869074 hasIssue "3" @default.
• W2138869074 hasLocation W21388690741 @default.
• W2138869074 hasLocation W21388690742 @default.
• W2138869074 hasLocation W21388690743 @default.
• W2138869074 hasLocation W21388690744 @default.
• W2138869074 hasLocation W21388690745 @default.
• W2138869074 hasOpenAccess W2138869074 @default.
• W2138869074 hasPrimaryLocation W21388690741 @default.
• W2138869074 hasRelatedWork W1512833508 @default.
• W2138869074 hasRelatedWork W1942185150 @default.
• W2138869074 hasRelatedWork W1986073869 @default.
• W2138869074 hasRelatedWork W1997681068 @default.
• W2138869074 hasRelatedWork W2026113054 @default.
• W2138869074 hasRelatedWork W2036774565 @default.
• W2138869074 hasRelatedWork W2062096378 @default.
• W2138869074 hasRelatedWork W2399868917 @default.
• W2138869074 hasRelatedWork W2411003582 @default.

• next