FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2138875239> ?p ?o ?g. }

• W2138875239 endingPage "1641" @default.
• W2138875239 startingPage "1630" @default.
• W2138875239 abstract "Abstract Using a conditional life or death screen in yeast, we have isolated a tomato (Lycopersicon esculentum) gene encoding a phospholipid hydroperoxide glutathione peroxidase (LePHGPx). The protein displayed reduced glutathione-dependent phospholipid hydroperoxide peroxidase activity, but differs from counterpart mammalian enzymes that instead contain an active seleno-Cys. LePHGPx functioned as a cytoprotector in yeast (Saccharomyces cerevisiae), preventing Bax, hydrogen peroxide, and heat stress induced cell death, while also delaying yeast senescence. When tobacco (Nicotiana tabacum) leaves were exposed to lethal levels of salt and heat stress, features associated with mammalian apoptosis were observed. Importantly, transient expression of LePHGPx protected tobacco leaves from salt and heat stress and suppressed the apoptotic-like features. As has been reported, conditional expression of Bax was lethal in tobacco, resulting in tissue collapse and membrane permeability to Evans blue. When LePHGPx was coexpressed with Bax, little cell death and no vital staining were observed. Moreover, stable expression of LePHGPx in tobacco conferred protection against the fungal phytopathogen Botrytis cinerea. Taken together, our data indicated that LePHGPx can protect plant tissue from a variety of stresses. Moreover, functional screens in yeast are a viable tool for the identification of plant genes that regulate cell death." @default.
• W2138875239 created "2016-06-24" @default.
• W2138875239 creator A5000432967 @default.
• W2138875239 creator A5016540922 @default.
• W2138875239 creator A5039206845 @default.
• W2138875239 creator A5080536679 @default.
• W2138875239 creator A5091237365 @default.
• W2138875239 date "2004-07-01" @default.
• W2138875239 modified "2023-10-16" @default.
• W2138875239 title "Tomato Phospholipid Hydroperoxide Glutathione Peroxidase Inhibits Cell Death Induced by Bax and Oxidative Stresses in Yeast and Plants" @default.
• W2138875239 cites W1479803402 @default.
• W2138875239 cites W1502227906 @default.
• W2138875239 cites W1526340496 @default.
• W2138875239 cites W1576869458 @default.
• W2138875239 cites W1578219504 @default.
• W2138875239 cites W1841006369 @default.
• W2138875239 cites W1970198120 @default.
• W2138875239 cites W1973349116 @default.
• W2138875239 cites W1979697395 @default.
• W2138875239 cites W1980969730 @default.
• W2138875239 cites W1994446224 @default.
• W2138875239 cites W1994811047 @default.
• W2138875239 cites W1999014341 @default.
• W2138875239 cites W1999098295 @default.
• W2138875239 cites W2005919395 @default.
• W2138875239 cites W2008117286 @default.
• W2138875239 cites W2012751277 @default.
• W2138875239 cites W2015837249 @default.
• W2138875239 cites W2017309092 @default.
• W2138875239 cites W2020289713 @default.
• W2138875239 cites W2023926016 @default.
• W2138875239 cites W2029493999 @default.
• W2138875239 cites W2031030183 @default.
• W2138875239 cites W2032405173 @default.
• W2138875239 cites W2036346552 @default.
• W2138875239 cites W2039220021 @default.
• W2138875239 cites W2042611670 @default.
• W2138875239 cites W2043948601 @default.
• W2138875239 cites W2043967616 @default.
• W2138875239 cites W2044117808 @default.
• W2138875239 cites W2048498745 @default.
• W2138875239 cites W2052853635 @default.
• W2138875239 cites W2064485732 @default.
• W2138875239 cites W2066639890 @default.
• W2138875239 cites W2067431766 @default.
• W2138875239 cites W2070275069 @default.
• W2138875239 cites W2079213174 @default.
• W2138875239 cites W2081155239 @default.
• W2138875239 cites W2086090484 @default.
• W2138875239 cites W2088114614 @default.
• W2138875239 cites W2088366214 @default.
• W2138875239 cites W2090677935 @default.
• W2138875239 cites W2098205649 @default.
• W2138875239 cites W2100194182 @default.
• W2138875239 cites W2102088119 @default.
• W2138875239 cites W2103010275 @default.
• W2138875239 cites W2104941151 @default.
• W2138875239 cites W2117547035 @default.
• W2138875239 cites W2121702473 @default.
• W2138875239 cites W2124167732 @default.
• W2138875239 cites W2129095580 @default.
• W2138875239 cites W2130490261 @default.
• W2138875239 cites W2131083942 @default.
• W2138875239 cites W2135208339 @default.
• W2138875239 cites W2146448235 @default.
• W2138875239 cites W2164276984 @default.
• W2138875239 cites W2164399204 @default.
• W2138875239 cites W2213073484 @default.
• W2138875239 cites W4236623446 @default.
• W2138875239 cites W4238506384 @default.
• W2138875239 cites W4251440173 @default.
• W2138875239 cites W4252826354 @default.
• W2138875239 cites W4300932895 @default.
• W2138875239 doi "https://doi.org/10.1104/pp.103.038091" @default.
• W2138875239 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/519077" @default.
• W2138875239 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15235116" @default.
• W2138875239 hasPublicationYear "2004" @default.
• W2138875239 type Work @default.
• W2138875239 sameAs 2138875239 @default.
• W2138875239 citedByCount "131" @default.
• W2138875239 countsByYear W21388752392012 @default.
• W2138875239 countsByYear W21388752392013 @default.
• W2138875239 countsByYear W21388752392014 @default.
• W2138875239 countsByYear W21388752392015 @default.
• W2138875239 countsByYear W21388752392016 @default.
• W2138875239 countsByYear W21388752392017 @default.
• W2138875239 countsByYear W21388752392018 @default.
• W2138875239 countsByYear W21388752392019 @default.
• W2138875239 countsByYear W21388752392020 @default.
• W2138875239 countsByYear W21388752392021 @default.
• W2138875239 countsByYear W21388752392022 @default.
• W2138875239 countsByYear W21388752392023 @default.
• W2138875239 crossrefType "journal-article" @default.
• W2138875239 hasAuthorship W2138875239A5000432967 @default.
• W2138875239 hasAuthorship W2138875239A5016540922 @default.
• W2138875239 hasAuthorship W2138875239A5039206845 @default.
• W2138875239 hasAuthorship W2138875239A5080536679 @default.
• W2138875239 hasAuthorship W2138875239A5091237365 @default.

• next