FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2138876608> ?p ?o ?g. }

• W2138876608 endingPage "3727" @default.
• W2138876608 startingPage "3716" @default.
• W2138876608 abstract "Greater understanding of the risk factors and mechanisms of incident dementia in stroke survivors is needed for prevention and management. There is limited information on the long-term consequences and forms of incident dementia in older stroke survivors. We recruited 355 patients aged >75 years from hospital-based stroke registers into a longitudinal study 3 months after stroke. At baseline none of the patients had dementia. Patients were genotyped for apolipoprotein E and assessed annually for cognition and development of incident dementia over up to 8 years of follow-up. The effect of baseline vascular risk factors upon incidence of dementia and mortality were estimated by Cox proportional regression analyses adjusted for age and gender. Standard neuropathological examination was performed to diagnose the first 50 cases that came to autopsy. We found that the median survival from the date of the index stroke was 6.72 years (95% confidence intervals: 6.38–7.05). During the follow-up of a mean time of 3.79 years, 23.9% of subjects were known to have developed dementia and 76.1% remained alive without dementia or died without dementia. The incidence of delayed dementia was calculated to be 6.32 cases per 100 person years whereas that for death or dementia was 8.62. Univariate and multivariate regression analyses showed that the most robust predictors of dementia included low (1.5 standard deviations below age-matched control group) baseline Cambridge Cognitive Examination executive function and memory scores, Geriatric Depression Scale score and three or more cardiovascular risk factors. Autopsy findings suggested that remarkably ≥75% of the demented stroke survivors met the current criteria for vascular dementia. Demented subjects tended to exhibit marginally greater neurofibrillary pathology including tauopathy and Lewy bodies and microinfarcts than non-demented survivors. Despite initial improvements in cognition following stroke in older stroke survivors, risk of progression to delayed dementia after stroke is substantial, but is related to the presence of vascular risk factors. Careful monitoring and treatment of modifiable vascular risk factors may be of benefit in preventing post-stroke dementia in the general population." @default.
• W2138876608 created "2016-06-24" @default.
• W2138876608 creator A5014848454 @default.
• W2138876608 creator A5021309430 @default.
• W2138876608 creator A5022971151 @default.
• W2138876608 creator A5027987037 @default.
• W2138876608 creator A5030646211 @default.
• W2138876608 creator A5035122709 @default.
• W2138876608 creator A5043388402 @default.
• W2138876608 creator A5053891607 @default.
• W2138876608 date "2011-12-01" @default.
• W2138876608 modified "2023-10-18" @default.
• W2138876608 title "Long term incidence of dementia, predictors of mortality and pathological diagnosis in older stroke survivors" @default.
• W2138876608 cites W1963910508 @default.
• W2138876608 cites W1970028556 @default.
• W2138876608 cites W1982204669 @default.
• W2138876608 cites W1989294823 @default.
• W2138876608 cites W1991144593 @default.
• W2138876608 cites W1992903980 @default.
• W2138876608 cites W1996372359 @default.
• W2138876608 cites W2003954746 @default.
• W2138876608 cites W2008678461 @default.
• W2138876608 cites W2015414121 @default.
• W2138876608 cites W2018040724 @default.
• W2138876608 cites W2023224182 @default.
• W2138876608 cites W2024814727 @default.
• W2138876608 cites W2028333291 @default.
• W2138876608 cites W2036945415 @default.
• W2138876608 cites W2037053046 @default.
• W2138876608 cites W2041203873 @default.
• W2138876608 cites W2041792754 @default.
• W2138876608 cites W2043644834 @default.
• W2138876608 cites W2071252381 @default.
• W2138876608 cites W2080950383 @default.
• W2138876608 cites W2081444704 @default.
• W2138876608 cites W2085846968 @default.
• W2138876608 cites W2087843925 @default.
• W2138876608 cites W2093978410 @default.
• W2138876608 cites W2094151256 @default.
• W2138876608 cites W2098621361 @default.
• W2138876608 cites W2100846474 @default.
• W2138876608 cites W2102198125 @default.
• W2138876608 cites W2107191158 @default.
• W2138876608 cites W2112150247 @default.
• W2138876608 cites W2116004992 @default.
• W2138876608 cites W2116687053 @default.
• W2138876608 cites W2118592618 @default.
• W2138876608 cites W2119151758 @default.
• W2138876608 cites W2125517700 @default.
• W2138876608 cites W2127516996 @default.
• W2138876608 cites W2128355406 @default.
• W2138876608 cites W2132851971 @default.
• W2138876608 cites W2134222173 @default.
• W2138876608 cites W2134768056 @default.
• W2138876608 cites W2138306169 @default.
• W2138876608 cites W2140959506 @default.
• W2138876608 cites W2142626061 @default.
• W2138876608 cites W2142825931 @default.
• W2138876608 cites W2145059764 @default.
• W2138876608 cites W2146363496 @default.
• W2138876608 cites W2147883225 @default.
• W2138876608 cites W2152641228 @default.
• W2138876608 cites W2159861873 @default.
• W2138876608 cites W2161420960 @default.
• W2138876608 cites W4231517048 @default.
• W2138876608 doi "https://doi.org/10.1093/brain/awr273" @default.
• W2138876608 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3235558" @default.
• W2138876608 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22171356" @default.
• W2138876608 hasPublicationYear "2011" @default.
• W2138876608 type Work @default.
• W2138876608 sameAs 2138876608 @default.
• W2138876608 citedByCount "165" @default.
• W2138876608 countsByYear W21388766082012 @default.
• W2138876608 countsByYear W21388766082013 @default.
• W2138876608 countsByYear W21388766082014 @default.
• W2138876608 countsByYear W21388766082015 @default.
• W2138876608 countsByYear W21388766082016 @default.
• W2138876608 countsByYear W21388766082017 @default.
• W2138876608 countsByYear W21388766082018 @default.
• W2138876608 countsByYear W21388766082019 @default.
• W2138876608 countsByYear W21388766082020 @default.
• W2138876608 countsByYear W21388766082021 @default.
• W2138876608 countsByYear W21388766082022 @default.
• W2138876608 countsByYear W21388766082023 @default.
• W2138876608 crossrefType "journal-article" @default.
• W2138876608 hasAuthorship W2138876608A5014848454 @default.
• W2138876608 hasAuthorship W2138876608A5021309430 @default.
• W2138876608 hasAuthorship W2138876608A5022971151 @default.
• W2138876608 hasAuthorship W2138876608A5027987037 @default.
• W2138876608 hasAuthorship W2138876608A5030646211 @default.
• W2138876608 hasAuthorship W2138876608A5035122709 @default.
• W2138876608 hasAuthorship W2138876608A5043388402 @default.
• W2138876608 hasAuthorship W2138876608A5053891607 @default.
• W2138876608 hasBestOaLocation W21388766081 @default.
• W2138876608 hasConcept C120665830 @default.
• W2138876608 hasConcept C121332964 @default.
• W2138876608 hasConcept C126322002 @default.
• W2138876608 hasConcept C127413603 @default.

• next