Matches in SemOpenAlex for { <https://semopenalex.org/work/W2139133180> ?p ?o ?g. }
- W2139133180 endingPage "815" @default.
- W2139133180 startingPage "806" @default.
- W2139133180 abstract "Administration of infliximab is associated with a well-recognised risk of infusion reactions. Lack of a mechanism-based rationale for their prevention, and absence of adequate and well-controlled studies, has led to the use of diverse empirical administration protocols. The aim of this study is to perform a systematic review of the evidence behind the strategies for preventing infusion reactions to infliximab, and for controlling the reactions once they occur.We conducted extensive search of electronic databases of MEDLINE [PubMed] for reports that communicate various aspects of infusion reactions to infliximab in IBD patients.We examined full texts of 105 potentially eligible articles. No randomised controlled trials that pre-defined infusion reaction as a primary outcome were found. Three RCTs evaluated infusion reactions as a secondary outcome; another four RCTs included infusion reactions in the safety evaluation analysis; and 62 additional studies focused on various aspects of mechanism/s, risk, primary and secondary preventive measures, and management algorithms. Seven studies were added by a manual search of reference lists of the relevant articles. A total of 76 original studies were included in quantitative analysis of the existing strategies.There is still paucity of systematic and controlled data on the risk, prevention, and management of infusion reactions to infliximab. We present working algorithms based on systematic and extensive review of the available data. More randomised controlled trials are needed in order to investigate the efficacy of the proposed preventive and management algorithms." @default.
- W2139133180 created "2016-06-24" @default.
- W2139133180 creator A5001233161 @default.
- W2139133180 creator A5005482074 @default.
- W2139133180 creator A5026843306 @default.
- W2139133180 creator A5029273084 @default.
- W2139133180 creator A5047907008 @default.
- W2139133180 creator A5049241638 @default.
- W2139133180 creator A5050127608 @default.
- W2139133180 creator A5062852819 @default.
- W2139133180 creator A5062860652 @default.
- W2139133180 creator A5085379005 @default.
- W2139133180 date "2015-06-19" @default.
- W2139133180 modified "2023-10-18" @default.
- W2139133180 title "Infliximab-Related Infusion Reactions: Systematic Review" @default.
- W2139133180 cites W1530709545 @default.
- W2139133180 cites W1536137871 @default.
- W2139133180 cites W1546652561 @default.
- W2139133180 cites W1606667043 @default.
- W2139133180 cites W1685882185 @default.
- W2139133180 cites W181130881 @default.
- W2139133180 cites W1903556778 @default.
- W2139133180 cites W1965377406 @default.
- W2139133180 cites W1967469454 @default.
- W2139133180 cites W1969692552 @default.
- W2139133180 cites W1969926626 @default.
- W2139133180 cites W1974542171 @default.
- W2139133180 cites W1976986990 @default.
- W2139133180 cites W1977241741 @default.
- W2139133180 cites W1979532130 @default.
- W2139133180 cites W1980254110 @default.
- W2139133180 cites W1980771888 @default.
- W2139133180 cites W1982879448 @default.
- W2139133180 cites W1983844355 @default.
- W2139133180 cites W1989429071 @default.
- W2139133180 cites W1992074983 @default.
- W2139133180 cites W1995043914 @default.
- W2139133180 cites W1997999969 @default.
- W2139133180 cites W2002852759 @default.
- W2139133180 cites W2002991484 @default.
- W2139133180 cites W2003573251 @default.
- W2139133180 cites W2005525382 @default.
- W2139133180 cites W2008629972 @default.
- W2139133180 cites W2009453084 @default.
- W2139133180 cites W2010872383 @default.
- W2139133180 cites W2013656349 @default.
- W2139133180 cites W2015408970 @default.
- W2139133180 cites W2017200913 @default.
- W2139133180 cites W2018178851 @default.
- W2139133180 cites W2024737355 @default.
- W2139133180 cites W2026116536 @default.
- W2139133180 cites W2026544302 @default.
- W2139133180 cites W2026631875 @default.
- W2139133180 cites W2027334329 @default.
- W2139133180 cites W2029209743 @default.
- W2139133180 cites W2031286145 @default.
- W2139133180 cites W2031484561 @default.
- W2139133180 cites W2035201594 @default.
- W2139133180 cites W2037146711 @default.
- W2139133180 cites W2039804759 @default.
- W2139133180 cites W2042214820 @default.
- W2139133180 cites W2043780895 @default.
- W2139133180 cites W2045466524 @default.
- W2139133180 cites W2051028531 @default.
- W2139133180 cites W2052476019 @default.
- W2139133180 cites W2055485216 @default.
- W2139133180 cites W2056011751 @default.
- W2139133180 cites W2056596058 @default.
- W2139133180 cites W2059263651 @default.
- W2139133180 cites W2073544361 @default.
- W2139133180 cites W2073999337 @default.
- W2139133180 cites W2076475114 @default.
- W2139133180 cites W2078867336 @default.
- W2139133180 cites W2078976651 @default.
- W2139133180 cites W2079404769 @default.
- W2139133180 cites W2081877352 @default.
- W2139133180 cites W2085433361 @default.
- W2139133180 cites W2086415546 @default.
- W2139133180 cites W2088629488 @default.
- W2139133180 cites W2093372305 @default.
- W2139133180 cites W2097998028 @default.
- W2139133180 cites W2105532585 @default.
- W2139133180 cites W2114990062 @default.
- W2139133180 cites W2117212747 @default.
- W2139133180 cites W2118186244 @default.
- W2139133180 cites W2118559127 @default.
- W2139133180 cites W2121050884 @default.
- W2139133180 cites W2122259238 @default.
- W2139133180 cites W2126807394 @default.
- W2139133180 cites W2127693350 @default.
- W2139133180 cites W2128440872 @default.
- W2139133180 cites W2129592053 @default.
- W2139133180 cites W2132885099 @default.
- W2139133180 cites W2134017663 @default.
- W2139133180 cites W2138534069 @default.
- W2139133180 cites W2141139109 @default.
- W2139133180 cites W2149309054 @default.
- W2139133180 cites W2151446490 @default.