Matches in SemOpenAlex for { <https://semopenalex.org/work/W2139217609> ?p ?o ?g. }
- W2139217609 endingPage "49" @default.
- W2139217609 startingPage "49" @default.
- W2139217609 abstract "Bovine coronavirus (BCoV) causes severe diarrhea in newborn calves, and is associated with winter dysentery in adult cattle and respiratory infections in calves and feedlot cattle. Although the Korean BCoV vaccine strain, BC94, was isolated in 1995, there has still been no report of a molecular characterization of the vaccine strain. To characterize the vaccine strain, relationships between BC94 and field strains were investigated, based on sequence analysis and cross-immunity. We determined the complete sequences of the HE, N, and S genes from BC94 and four NVRQS isolates (SUN5, A3, 0501, 0502). Due to its major role in antigenicity, the spike proteins of the BCoVs were analyzed. BC94 showed distinctive genetic divergence from field isolates collected from 2002 to 2005. BC94, SUN5, and A3 had no virulence-specific sequence and there was a single amino acid change, from asparagine to lysine at residue 175, in the polymorphic region. Strains 0501 and 0502 had virulence-specific sequences at all seven sites. Although the recently isolated Korean BCoVs and BC94 were genetically different, the cleavage site of spike genes at 763~768 (KRRSRR) and the antigenic domain II of the spike protein, amino acid position 528, were conserved in all NVRQS isolates. The antigenic relatedness of KCD9, representative of recent Korean BCoVs, was compared with the Korean vaccine strain BC94. KCD9 showed cross-reactivity against BC94 by virus neutralization (VN) test. These results suggest that BC94 is antigenically closely related to field isolates and is still effective as a vaccine strain." @default.
- W2139217609 created "2016-06-24" @default.
- W2139217609 creator A5022573350 @default.
- W2139217609 creator A5046989134 @default.
- W2139217609 creator A5071658884 @default.
- W2139217609 creator A5072106250 @default.
- W2139217609 date "2010-01-01" @default.
- W2139217609 modified "2023-10-01" @default.
- W2139217609 title "Cross-reactivity of Vaccine and Fields Strains of Bovine Coronaviruses in Korea" @default.
- W2139217609 cites W1542641435 @default.
- W2139217609 cites W1811783050 @default.
- W2139217609 cites W1847926290 @default.
- W2139217609 cites W1891303982 @default.
- W2139217609 cites W1963991418 @default.
- W2139217609 cites W1972567954 @default.
- W2139217609 cites W1979507518 @default.
- W2139217609 cites W1985328913 @default.
- W2139217609 cites W1987051173 @default.
- W2139217609 cites W2015179413 @default.
- W2139217609 cites W2019400272 @default.
- W2139217609 cites W2029775053 @default.
- W2139217609 cites W2038758902 @default.
- W2139217609 cites W2048538637 @default.
- W2139217609 cites W2052826004 @default.
- W2139217609 cites W2061397668 @default.
- W2139217609 cites W2064998490 @default.
- W2139217609 cites W2067279877 @default.
- W2139217609 cites W2087610314 @default.
- W2139217609 cites W2119400984 @default.
- W2139217609 cites W2124042319 @default.
- W2139217609 cites W2127485790 @default.
- W2139217609 cites W2134044385 @default.
- W2139217609 cites W2141308245 @default.
- W2139217609 cites W2144917489 @default.
- W2139217609 cites W2145122445 @default.
- W2139217609 cites W2147272141 @default.
- W2139217609 cites W2154189825 @default.
- W2139217609 cites W2168848638 @default.
- W2139217609 cites W2170553234 @default.
- W2139217609 cites W276631229 @default.
- W2139217609 cites W357102830 @default.
- W2139217609 cites W4206431656 @default.
- W2139217609 doi "https://doi.org/10.4167/jbv.2010.40.1.49" @default.
- W2139217609 hasPublicationYear "2010" @default.
- W2139217609 type Work @default.
- W2139217609 sameAs 2139217609 @default.
- W2139217609 citedByCount "1" @default.
- W2139217609 crossrefType "journal-article" @default.
- W2139217609 hasAuthorship W2139217609A5022573350 @default.
- W2139217609 hasAuthorship W2139217609A5046989134 @default.
- W2139217609 hasAuthorship W2139217609A5071658884 @default.
- W2139217609 hasAuthorship W2139217609A5072106250 @default.
- W2139217609 hasBestOaLocation W21392176091 @default.
- W2139217609 hasConcept C104317684 @default.
- W2139217609 hasConcept C105702510 @default.
- W2139217609 hasConcept C142724271 @default.
- W2139217609 hasConcept C147483822 @default.
- W2139217609 hasConcept C159047783 @default.
- W2139217609 hasConcept C2522874641 @default.
- W2139217609 hasConcept C2776810377 @default.
- W2139217609 hasConcept C2777227250 @default.
- W2139217609 hasConcept C2777648638 @default.
- W2139217609 hasConcept C2778022156 @default.
- W2139217609 hasConcept C2779026604 @default.
- W2139217609 hasConcept C2779134260 @default.
- W2139217609 hasConcept C2779142602 @default.
- W2139217609 hasConcept C2781367151 @default.
- W2139217609 hasConcept C3008058167 @default.
- W2139217609 hasConcept C3020064264 @default.
- W2139217609 hasConcept C524204448 @default.
- W2139217609 hasConcept C54355233 @default.
- W2139217609 hasConcept C60987743 @default.
- W2139217609 hasConcept C61053724 @default.
- W2139217609 hasConcept C71924100 @default.
- W2139217609 hasConcept C86803240 @default.
- W2139217609 hasConcept C89423630 @default.
- W2139217609 hasConceptScore W2139217609C104317684 @default.
- W2139217609 hasConceptScore W2139217609C105702510 @default.
- W2139217609 hasConceptScore W2139217609C142724271 @default.
- W2139217609 hasConceptScore W2139217609C147483822 @default.
- W2139217609 hasConceptScore W2139217609C159047783 @default.
- W2139217609 hasConceptScore W2139217609C2522874641 @default.
- W2139217609 hasConceptScore W2139217609C2776810377 @default.
- W2139217609 hasConceptScore W2139217609C2777227250 @default.
- W2139217609 hasConceptScore W2139217609C2777648638 @default.
- W2139217609 hasConceptScore W2139217609C2778022156 @default.
- W2139217609 hasConceptScore W2139217609C2779026604 @default.
- W2139217609 hasConceptScore W2139217609C2779134260 @default.
- W2139217609 hasConceptScore W2139217609C2779142602 @default.
- W2139217609 hasConceptScore W2139217609C2781367151 @default.
- W2139217609 hasConceptScore W2139217609C3008058167 @default.
- W2139217609 hasConceptScore W2139217609C3020064264 @default.
- W2139217609 hasConceptScore W2139217609C524204448 @default.
- W2139217609 hasConceptScore W2139217609C54355233 @default.
- W2139217609 hasConceptScore W2139217609C60987743 @default.
- W2139217609 hasConceptScore W2139217609C61053724 @default.
- W2139217609 hasConceptScore W2139217609C71924100 @default.
- W2139217609 hasConceptScore W2139217609C86803240 @default.