Matches in SemOpenAlex for { <https://semopenalex.org/work/W2139299821> ?p ?o ?g. }
- W2139299821 endingPage "1756" @default.
- W2139299821 startingPage "1744" @default.
- W2139299821 abstract "Temporal lobe epilepsy (TLE) is one of the most common forms of drug-resistant epilepsy. Previous studies have indicated that the TLE-related impairments existed in extensive local functional networks. However, little is known about the alterations in the topological properties of whole brain functional networks.In this study, we acquired resting-state BOLD-fMRI (rsfMRI) data from 26 TLE patients and 25 healthy controls, constructed their whole brain functional networks, compared the differences in topological parameters between the TLE patients and the controls, and analyzed the correlation between the altered topological properties and the epilepsy duration.The TLE patients showed significant increases in clustering coefficient and characteristic path length, but significant decrease in global efficiency compared to the controls. We also found altered nodal parameters in several regions in the TLE patients, such as the bilateral angular gyri, left middle temporal gyrus, right hippocampus, triangular part of left inferior frontal gyrus, left inferior parietal but supramarginal and angular gyri, and left parahippocampus gyrus. Further correlation analysis showed that the local efficiency of the TLE patients correlated positively with the epilepsy duration.Our results indicated the disrupted topological properties of whole brain functional networks in TLE patients.Our findings indicated the TLE-related impairments in the whole brain functional networks, which may help us to understand the clinical symptoms of TLE patients and offer a clue for the diagnosis and treatment of the TLE patients." @default.
- W2139299821 created "2016-06-24" @default.
- W2139299821 creator A5002732226 @default.
- W2139299821 creator A5004941336 @default.
- W2139299821 creator A5014951300 @default.
- W2139299821 creator A5015566430 @default.
- W2139299821 creator A5022483197 @default.
- W2139299821 creator A5023679542 @default.
- W2139299821 creator A5059394465 @default.
- W2139299821 creator A5065007956 @default.
- W2139299821 creator A5072315063 @default.
- W2139299821 creator A5088773627 @default.
- W2139299821 date "2014-09-01" @default.
- W2139299821 modified "2023-09-27" @default.
- W2139299821 title "Graph theoretical analysis reveals disrupted topological properties of whole brain functional networks in temporal lobe epilepsy" @default.
- W2139299821 cites W1595033594 @default.
- W2139299821 cites W1606742450 @default.
- W2139299821 cites W1760829075 @default.
- W2139299821 cites W1780052458 @default.
- W2139299821 cites W1970699942 @default.
- W2139299821 cites W1971986290 @default.
- W2139299821 cites W1974309894 @default.
- W2139299821 cites W1974706776 @default.
- W2139299821 cites W1974764791 @default.
- W2139299821 cites W1975402676 @default.
- W2139299821 cites W1976781461 @default.
- W2139299821 cites W1979426401 @default.
- W2139299821 cites W1983537704 @default.
- W2139299821 cites W1994184572 @default.
- W2139299821 cites W1996630013 @default.
- W2139299821 cites W1997346893 @default.
- W2139299821 cites W1998095942 @default.
- W2139299821 cites W1999345164 @default.
- W2139299821 cites W1999653836 @default.
- W2139299821 cites W2000101415 @default.
- W2139299821 cites W2000102994 @default.
- W2139299821 cites W2008074642 @default.
- W2139299821 cites W2011961540 @default.
- W2139299821 cites W2013605485 @default.
- W2139299821 cites W2020617938 @default.
- W2139299821 cites W2025948330 @default.
- W2139299821 cites W2028006756 @default.
- W2139299821 cites W2028470648 @default.
- W2139299821 cites W2030902100 @default.
- W2139299821 cites W2036146354 @default.
- W2139299821 cites W2037557484 @default.
- W2139299821 cites W2038068904 @default.
- W2139299821 cites W2038752970 @default.
- W2139299821 cites W2041216092 @default.
- W2139299821 cites W2041951497 @default.
- W2139299821 cites W2046473892 @default.
- W2139299821 cites W2048653316 @default.
- W2139299821 cites W2051633111 @default.
- W2139299821 cites W2053665546 @default.
- W2139299821 cites W2056333163 @default.
- W2139299821 cites W2058046532 @default.
- W2139299821 cites W2061446261 @default.
- W2139299821 cites W2063404606 @default.
- W2139299821 cites W2064089300 @default.
- W2139299821 cites W2067219344 @default.
- W2139299821 cites W2072632178 @default.
- W2139299821 cites W2075026451 @default.
- W2139299821 cites W2079129033 @default.
- W2139299821 cites W2079812616 @default.
- W2139299821 cites W2080403608 @default.
- W2139299821 cites W2080847728 @default.
- W2139299821 cites W2085382422 @default.
- W2139299821 cites W2088858238 @default.
- W2139299821 cites W2089970918 @default.
- W2139299821 cites W2091698784 @default.
- W2139299821 cites W2092655084 @default.
- W2139299821 cites W2093606787 @default.
- W2139299821 cites W2094526440 @default.
- W2139299821 cites W2095491050 @default.
- W2139299821 cites W2098492043 @default.
- W2139299821 cites W2100089294 @default.
- W2139299821 cites W2102705657 @default.
- W2139299821 cites W2112090702 @default.
- W2139299821 cites W2120168996 @default.
- W2139299821 cites W2121765190 @default.
- W2139299821 cites W2124417895 @default.
- W2139299821 cites W2126012718 @default.
- W2139299821 cites W2130513423 @default.
- W2139299821 cites W2131055855 @default.
- W2139299821 cites W2131494589 @default.
- W2139299821 cites W2134248637 @default.
- W2139299821 cites W2134739388 @default.
- W2139299821 cites W2135475851 @default.
- W2139299821 cites W2138991775 @default.
- W2139299821 cites W2142317829 @default.
- W2139299821 cites W2144827143 @default.
- W2139299821 cites W2145397972 @default.
- W2139299821 cites W2145902966 @default.
- W2139299821 cites W2149116050 @default.
- W2139299821 cites W2153436764 @default.
- W2139299821 cites W2154997432 @default.
- W2139299821 cites W2157909028 @default.
- W2139299821 cites W2159242554 @default.