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- W2139436350 abstract "Acute liver failure (ALF) is a medical emergency requiring immediate evaluation for liver transplantation. We describe an unusual case of a patient who presented with ascites, jaundice, and encephalopathy and was found to have ALF due to natural killer (NK)-like T cell leukemia/lymphoma. The key immunophenotype was CD2+, CD3+, CD7+, CD56+. This diagnosis, which was based on findings in the peripheral blood and ascitic fluid, was confirmed with liver biopsy, and was a contraindication to liver transplantation. A review of the literature shows that hematologic malignancies are an uncommon cause of fulminant hepatic failure, and that NK-like T-cell leukemia/lymphoma is a relatively recently recognized entity which is characteristically CD3+ and CD56+. This case demonstrates that liver biopsy is essential in diagnosing unusual causes of acute liver failure, and that infiltration of the liver with NK-like T-cell lymphoma/leukemia can cause acute liver failure." @default.
- W2139436350 created "2016-06-24" @default.
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- W2139436350 date "2006-01-01" @default.
- W2139436350 modified "2023-09-23" @default.
- W2139436350 title "Acute liver failure due to natural killer-like T-cell leukemia/lymphoma: A case report and review of the Literature" @default.
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- W2139436350 doi "https://doi.org/10.3748/wjg.v12.i25.4089" @default.
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