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• W2139562707 abstract "Programmed cell death (PCD) is a common defense response in plants against pathogen infection. The recently cloned ACD6 gene was identified in an Arabidopsis mutant, accelerated cell death 6 ( acd6 ), that undergoes PCD in the absence of a pathogen challenge. ACD6 is a founding member of a large family of genes that encode proteins with a short amino-terminal region, nine ankyrin repeats in the middle, and five putative transmembrane domains in the carboxyl-terminal region. Characterization of the original gain-of-function acd6 mutant and a transferred-DNA knockout mutant acd6-T showed that ACD6 is an activator of the defense pathway against bacterial pathogens and plays a role in PCD through regulation of the defense signal salicylic acid (SA). SA mediates not only downstream pathogenesis-related ( PR ) genes, which encode proteins with antimicrobial activities, but also ACD6 , forming a feedback signal amplification loop." @default.
• W2139562707 created "2016-06-24" @default.
• W2139562707 creator A5011301116 @default.
• W2139562707 date "2004-02-24" @default.
• W2139562707 modified "2023-09-29" @default.
• W2139562707 title "The Role of Membrane-Bound Ankyrin-Repeat Protein ACD6 in Programmed Cell Death and Plant Defense" @default.
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• W2139562707 doi "https://doi.org/10.1126/stke.2212004pe6" @default.
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