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- W2139568100 abstract "γ-Aminobutyrate (GABA) is a ubiquitous four-C, nonprotein, amino acid that has been linked to stress, signaling, and storage in plants. In this paper, we discuss analytical, enzyme-linked, and colorimetric methods for analyzing GABA and related metabolites, and review tracer evidence for the derivation of GABA from glutamate and its subsequent catabolism to succinic semialdehyde and either succinate or γ-hydroxybutyrate. Also, we describe biochemical, complementation, bioinformatic, recombinant, and modelling strategies for identifying genes and investigating properties of the encoded proteins responsible for transport and metabolism of GABA. For Arabidopsis, evidence supports the involvement of a plasma membrane GABA transporter, a mitochondrial GABA permease, a cytosolic Ca 2+ /calmodulin- and pH-regulated cytosolic glutamate decarboxylase, a pyruvate- and glyoxylate-regulated mitochondrial GABA transaminase, a redox-regulated mitochondrial succinic semialdehyde dehydrogenase, and redox-regulated glyoxylate/succinic semialdehyde reductases located in both cytosol and plastid, respectively. This simple biochemical model does not account for species and tissue differences in the isoform complement of GABA pathway enzymes or transcriptional control of the pathway. In a companion review, we provide a more integrated view of GABA metabolism and function." @default.
- W2139568100 created "2016-06-24" @default.
- W2139568100 creator A5004914794 @default.
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- W2139568100 creator A5029740245 @default.
- W2139568100 creator A5043679100 @default.
- W2139568100 creator A5045437435 @default.
- W2139568100 date "2012-08-01" @default.
- W2139568100 modified "2023-10-18" @default.
- W2139568100 title "Strategies and tools for studying the metabolism and function of γ-aminobutyrate in plants. I. Pathway structure" @default.
- W2139568100 cites W124909345 @default.
- W2139568100 cites W1487772730 @default.
- W2139568100 cites W1502362372 @default.
- W2139568100 cites W1521238198 @default.
- W2139568100 cites W1537245269 @default.
- W2139568100 cites W1546614225 @default.
- W2139568100 cites W1547917441 @default.
- W2139568100 cites W1549909691 @default.
- W2139568100 cites W1555714214 @default.
- W2139568100 cites W1573255518 @default.
- W2139568100 cites W1586416974 @default.
- W2139568100 cites W1588071693 @default.
- W2139568100 cites W1603572964 @default.
- W2139568100 cites W1604989470 @default.
- W2139568100 cites W172187038 @default.
- W2139568100 cites W1800534215 @default.
- W2139568100 cites W1910207539 @default.
- W2139568100 cites W193529727 @default.
- W2139568100 cites W1939566429 @default.
- W2139568100 cites W1966656860 @default.
- W2139568100 cites W1966738386 @default.
- W2139568100 cites W1967282265 @default.
- W2139568100 cites W1967285475 @default.
- W2139568100 cites W1971285509 @default.
- W2139568100 cites W1973421997 @default.
- W2139568100 cites W1973851509 @default.
- W2139568100 cites W1974347774 @default.
- W2139568100 cites W1974447827 @default.
- W2139568100 cites W1975630364 @default.
- W2139568100 cites W1976009156 @default.
- W2139568100 cites W1977567492 @default.
- W2139568100 cites W1977614440 @default.
- W2139568100 cites W1978781045 @default.
- W2139568100 cites W1979989367 @default.
- W2139568100 cites W1981313399 @default.
- W2139568100 cites W1983470248 @default.
- W2139568100 cites W1983533258 @default.
- W2139568100 cites W1983642244 @default.
- W2139568100 cites W1984120459 @default.
- W2139568100 cites W1985707407 @default.
- W2139568100 cites W1987024254 @default.
- W2139568100 cites W1988574145 @default.
- W2139568100 cites W1990354831 @default.
- W2139568100 cites W1991898018 @default.
- W2139568100 cites W1992932332 @default.
- W2139568100 cites W1993669284 @default.
- W2139568100 cites W1995888001 @default.
- W2139568100 cites W1996320023 @default.
- W2139568100 cites W1998638687 @default.
- W2139568100 cites W2004805804 @default.
- W2139568100 cites W2005349247 @default.
- W2139568100 cites W2006241825 @default.
- W2139568100 cites W2007144886 @default.
- W2139568100 cites W2007601852 @default.
- W2139568100 cites W2008577902 @default.
- W2139568100 cites W2009957008 @default.
- W2139568100 cites W2010014719 @default.
- W2139568100 cites W2013357048 @default.
- W2139568100 cites W2013580743 @default.
- W2139568100 cites W2016408888 @default.
- W2139568100 cites W2016943354 @default.
- W2139568100 cites W2017329736 @default.
- W2139568100 cites W2020165459 @default.
- W2139568100 cites W2020251153 @default.
- W2139568100 cites W2020968364 @default.
- W2139568100 cites W2021105899 @default.
- W2139568100 cites W2021735820 @default.
- W2139568100 cites W2022172251 @default.
- W2139568100 cites W2022766793 @default.
- W2139568100 cites W2022966294 @default.
- W2139568100 cites W2026377781 @default.
- W2139568100 cites W2026995830 @default.
- W2139568100 cites W2027335491 @default.
- W2139568100 cites W2027337261 @default.
- W2139568100 cites W2027440710 @default.
- W2139568100 cites W2027610017 @default.
- W2139568100 cites W2028432660 @default.
- W2139568100 cites W2029292626 @default.
- W2139568100 cites W2029314744 @default.
- W2139568100 cites W2029616336 @default.
- W2139568100 cites W2030083304 @default.
- W2139568100 cites W2033016999 @default.
- W2139568100 cites W2035456253 @default.
- W2139568100 cites W2036562713 @default.
- W2139568100 cites W2038208159 @default.
- W2139568100 cites W2038361699 @default.
- W2139568100 cites W2039216346 @default.
- W2139568100 cites W2042021074 @default.