FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2139610590> ?p ?o ?g. }

• W2139610590 abstract "Background Sore throat is a common reason for people to present for medical care. Although it remits spontaneously, primary care doctors commonly prescribe antibiotics for it. Objectives To assess the benefits of antibiotics for sore throat for patients in primary care settings. Search methods We searched CENTRAL 2013, Issue 6, MEDLINE (January 1966 to July week 1, 2013) and EMBASE (January 1990 to July 2013). Selection criteria Randomised controlled trials (RCTs) or quasi‐RCTs of antibiotics versus control assessing typical sore throat symptoms or complications. Data collection and analysis Two review authors independently screened studies for inclusion and extracted data. We resolved differences in opinion by discussion. We contacted trial authors from three studies for additional information. Main results We included 27 trials with 12,835 cases of sore throat. We did not identify any new trials in this 2013 update. 1. Symptoms Throat soreness and fever were reduced by about half by using antibiotics. The greatest difference was seen at day three. The number needed to treat to benefit (NNTB) to prevent one sore throat at day three was less than six; at week one it was 21. 2. Non‐suppurative complications The trend was antibiotics protecting against acute glomerulonephritis but there were too few cases to be sure. Several studies found antibiotics reduced acute rheumatic fever by more than two‐thirds within one month (risk ratio (RR) 0.27; 95% confidence interval (CI) 0.12 to 0.60). 3. Suppurative complications Antibiotics reduced the incidence of acute otitis media within 14 days (RR 0.30; 95% CI 0.15 to 0.58); acute sinusitis within 14 days (RR 0.48; 95% CI 0.08 to 2.76); and quinsy within two months (RR 0.15; 95% CI 0.05 to 0.47) compared to those taking placebo. 4. Subgroup analyses of symptom reduction Antibiotics were more effective against symptoms at day three (RR 0.58; 95% CI 0.48 to 0.71) if throat swabs were positive for Streptococcus, compared to RR 0.78; 95% CI 0.63 to 0.97 if negative. Similarly at week one the RR was 0.29 (95% CI 0.12 to 0.70) for positive and 0.73 (95% CI 0.50 to 1.07) for negative Streptococcus swabs. Authors' conclusions Antibiotics confer relative benefits in the treatment of sore throat. However, the absolute benefits are modest. Protecting sore throat sufferers against suppurative and non‐suppurative complications in high‐income countries requires treating many with antibiotics for one to benefit. This NNTB may be lower in low‐income countries. Antibiotics shorten the duration of symptoms by about 16 hours overall." @default.
• W2139610590 created "2016-06-24" @default.
• W2139610590 creator A5005751643 @default.
• W2139610590 creator A5021223667 @default.
• W2139610590 creator A5021292619 @default.
• W2139610590 date "2013-11-05" @default.
• W2139610590 modified "2023-10-18" @default.
• W2139610590 title "Antibiotics for sore throat" @default.
• W2139610590 cites W122718341 @default.
• W2139610590 cites W1541717636 @default.
• W2139610590 cites W1544684068 @default.
• W2139610590 cites W1574861237 @default.
• W2139610590 cites W1963994823 @default.
• W2139610590 cites W1966666594 @default.
• W2139610590 cites W1968479649 @default.
• W2139610590 cites W1968559671 @default.
• W2139610590 cites W1971784898 @default.
• W2139610590 cites W1974978864 @default.
• W2139610590 cites W1975523977 @default.
• W2139610590 cites W1976124623 @default.
• W2139610590 cites W1977358514 @default.
• W2139610590 cites W1980056709 @default.
• W2139610590 cites W1991854222 @default.
• W2139610590 cites W1994288358 @default.
• W2139610590 cites W2004914932 @default.
• W2139610590 cites W2004994207 @default.
• W2139610590 cites W2010784304 @default.
• W2139610590 cites W2011912767 @default.
• W2139610590 cites W2015045556 @default.
• W2139610590 cites W2016948860 @default.
• W2139610590 cites W2024949605 @default.
• W2139610590 cites W2028331431 @default.
• W2139610590 cites W2029932121 @default.
• W2139610590 cites W2031596720 @default.
• W2139610590 cites W2042312754 @default.
• W2139610590 cites W2042342778 @default.
• W2139610590 cites W2045596153 @default.
• W2139610590 cites W2045716363 @default.
• W2139610590 cites W2053119494 @default.
• W2139610590 cites W2055589994 @default.
• W2139610590 cites W2057262504 @default.
• W2139610590 cites W2058992365 @default.
• W2139610590 cites W2073630472 @default.
• W2139610590 cites W2076604658 @default.
• W2139610590 cites W2079450699 @default.
• W2139610590 cites W2081114804 @default.
• W2139610590 cites W2083964002 @default.
• W2139610590 cites W2088231729 @default.
• W2139610590 cites W2089772209 @default.
• W2139610590 cites W2122805667 @default.
• W2139610590 cites W2163846754 @default.
• W2139610590 cites W2168697444 @default.
• W2139610590 cites W2320938607 @default.
• W2139610590 cites W2321109909 @default.
• W2139610590 cites W2324202712 @default.
• W2139610590 cites W2330792212 @default.
• W2139610590 cites W2336444908 @default.
• W2139610590 cites W2337178040 @default.
• W2139610590 cites W2442373782 @default.
• W2139610590 cites W4211010731 @default.
• W2139610590 cites W4234669864 @default.
• W2139610590 cites W4239958341 @default.
• W2139610590 cites W4240460612 @default.
• W2139610590 cites W4247981334 @default.
• W2139610590 cites W4250385459 @default.
• W2139610590 cites W4254658862 @default.
• W2139610590 cites W4300704554 @default.
• W2139610590 cites W70735374 @default.
• W2139610590 doi "https://doi.org/10.1002/14651858.cd000023.pub4" @default.
• W2139610590 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6457983" @default.
• W2139610590 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24190439" @default.
• W2139610590 hasPublicationYear "2013" @default.
• W2139610590 type Work @default.
• W2139610590 sameAs 2139610590 @default.
• W2139610590 citedByCount "372" @default.
• W2139610590 countsByYear W21396105902012 @default.
• W2139610590 countsByYear W21396105902013 @default.
• W2139610590 countsByYear W21396105902014 @default.
• W2139610590 countsByYear W21396105902015 @default.
• W2139610590 countsByYear W21396105902016 @default.
• W2139610590 countsByYear W21396105902017 @default.
• W2139610590 countsByYear W21396105902018 @default.
• W2139610590 countsByYear W21396105902019 @default.
• W2139610590 countsByYear W21396105902020 @default.
• W2139610590 countsByYear W21396105902021 @default.
• W2139610590 countsByYear W21396105902022 @default.
• W2139610590 countsByYear W21396105902023 @default.
• W2139610590 crossrefType "journal-article" @default.
• W2139610590 hasAuthorship W2139610590A5005751643 @default.
• W2139610590 hasAuthorship W2139610590A5021223667 @default.
• W2139610590 hasAuthorship W2139610590A5021292619 @default.
• W2139610590 hasBestOaLocation W21396105902 @default.
• W2139610590 hasConcept C120665830 @default.
• W2139610590 hasConcept C121332964 @default.
• W2139610590 hasConcept C126322002 @default.
• W2139610590 hasConcept C141071460 @default.
• W2139610590 hasConcept C168563851 @default.
• W2139610590 hasConcept C177713679 @default.
• W2139610590 hasConcept C2776989088 @default.
• W2139610590 hasConcept C2777870961 @default.

• next