FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2139621750> ?p ?o ?g. }

• W2139621750 endingPage "20" @default.
• W2139621750 startingPage "11" @default.
• W2139621750 abstract "In patients with acute ischemic stroke caused by a proximal intracranial arterial occlusion, intraarterial treatment is highly effective for emergency revascularization. However, proof of a beneficial effect on functional outcome is lacking.We randomly assigned eligible patients to either intraarterial treatment plus usual care or usual care alone. Eligible patients had a proximal arterial occlusion in the anterior cerebral circulation that was confirmed on vessel imaging and that could be treated intraarterially within 6 hours after symptom onset. The primary outcome was the modified Rankin scale score at 90 days; this categorical scale measures functional outcome, with scores ranging from 0 (no symptoms) to 6 (death). The treatment effect was estimated with ordinal logistic regression as a common odds ratio, adjusted for prespecified prognostic factors. The adjusted common odds ratio measured the likelihood that intraarterial treatment would lead to lower modified Rankin scores, as compared with usual care alone (shift analysis).We enrolled 500 patients at 16 medical centers in The Netherlands (233 assigned to intraarterial treatment and 267 to usual care alone). The mean age was 65 years (range, 23 to 96), and 445 patients (89.0%) were treated with intravenous alteplase before randomization. Retrievable stents were used in 190 of the 233 patients (81.5%) assigned to intraarterial treatment. The adjusted common odds ratio was 1.67 (95% confidence interval [CI], 1.21 to 2.30). There was an absolute difference of 13.5 percentage points (95% CI, 5.9 to 21.2) in the rate of functional independence (modified Rankin score, 0 to 2) in favor of the intervention (32.6% vs. 19.1%). There were no significant differences in mortality or the occurrence of symptomatic intracerebral hemorrhage.In patients with acute ischemic stroke caused by a proximal intracranial occlusion of the anterior circulation, intraarterial treatment administered within 6 hours after stroke onset was effective and safe. (Funded by the Dutch Heart Foundation and others; MR CLEAN Netherlands Trial Registry number, NTR1804, and Current Controlled Trials number, ISRCTN10888758.)." @default.
• W2139621750 created "2016-06-24" @default.
• W2139621750 creator A5000185581 @default.
• W2139621750 creator A5001296846 @default.
• W2139621750 creator A5001542739 @default.
• W2139621750 creator A5001811742 @default.
• W2139621750 creator A5004625730 @default.
• W2139621750 creator A5006225939 @default.
• W2139621750 creator A5008171422 @default.
• W2139621750 creator A5008698288 @default.
• W2139621750 creator A5009172577 @default.
• W2139621750 creator A5015773391 @default.
• W2139621750 creator A5017884714 @default.
• W2139621750 creator A5018998576 @default.
• W2139621750 creator A5020195975 @default.
• W2139621750 creator A5023767624 @default.
• W2139621750 creator A5024309954 @default.
• W2139621750 creator A5025212881 @default.
• W2139621750 creator A5026314299 @default.
• W2139621750 creator A5026647662 @default.
• W2139621750 creator A5034038759 @default.
• W2139621750 creator A5034620034 @default.
• W2139621750 creator A5034901547 @default.
• W2139621750 creator A5042663323 @default.
• W2139621750 creator A5043499668 @default.
• W2139621750 creator A5043988761 @default.
• W2139621750 creator A5045535833 @default.
• W2139621750 creator A5046434206 @default.
• W2139621750 creator A5048072814 @default.
• W2139621750 creator A5050658147 @default.
• W2139621750 creator A5050974999 @default.
• W2139621750 creator A5051762378 @default.
• W2139621750 creator A5052180742 @default.
• W2139621750 creator A5053336686 @default.
• W2139621750 creator A5053444039 @default.
• W2139621750 creator A5053501423 @default.
• W2139621750 creator A5054195370 @default.
• W2139621750 creator A5055304531 @default.
• W2139621750 creator A5058817860 @default.
• W2139621750 creator A5061133593 @default.
• W2139621750 creator A5062338618 @default.
• W2139621750 creator A5062870043 @default.
• W2139621750 creator A5063013324 @default.
• W2139621750 creator A5063117815 @default.
• W2139621750 creator A5063851108 @default.
• W2139621750 creator A5067039906 @default.
• W2139621750 creator A5068014810 @default.
• W2139621750 creator A5069603301 @default.
• W2139621750 creator A5070233691 @default.
• W2139621750 creator A5074643232 @default.
• W2139621750 creator A5074953984 @default.
• W2139621750 creator A5080118882 @default.
• W2139621750 creator A5080157448 @default.
• W2139621750 creator A5081542140 @default.
• W2139621750 creator A5086830720 @default.
• W2139621750 creator A5086945563 @default.
• W2139621750 creator A5089033425 @default.
• W2139621750 creator A5091435927 @default.
• W2139621750 date "2015-01-01" @default.
• W2139621750 modified "2023-10-16" @default.
• W2139621750 title "A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke" @default.
• W2139621750 cites W1969661146 @default.
• W2139621750 cites W1971247823 @default.
• W2139621750 cites W2012982706 @default.
• W2139621750 cites W2014796100 @default.
• W2139621750 cites W2032871494 @default.
• W2139621750 cites W2042819373 @default.
• W2139621750 cites W2050880768 @default.
• W2139621750 cites W2060832182 @default.
• W2139621750 cites W2062383335 @default.
• W2139621750 cites W2084521665 @default.
• W2139621750 cites W2088362183 @default.
• W2139621750 cites W2094130955 @default.
• W2139621750 cites W2099706007 @default.
• W2139621750 cites W2105417725 @default.
• W2139621750 cites W2111559905 @default.
• W2139621750 cites W2113442572 @default.
• W2139621750 cites W2114603310 @default.
• W2139621750 cites W2128757394 @default.
• W2139621750 cites W2131192729 @default.
• W2139621750 cites W2134066226 @default.
• W2139621750 cites W2139703299 @default.
• W2139621750 cites W2146307187 @default.
• W2139621750 cites W2148656951 @default.
• W2139621750 cites W2171165037 @default.
• W2139621750 cites W2322575972 @default.
• W2139621750 cites W2473786944 @default.
• W2139621750 doi "https://doi.org/10.1056/nejmoa1411587" @default.
• W2139621750 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25517348" @default.
• W2139621750 hasPublicationYear "2015" @default.
• W2139621750 type Work @default.
• W2139621750 sameAs 2139621750 @default.
• W2139621750 citedByCount "5047" @default.
• W2139621750 countsByYear W21396217502014 @default.
• W2139621750 countsByYear W21396217502015 @default.
• W2139621750 countsByYear W21396217502016 @default.
• W2139621750 countsByYear W21396217502017 @default.
• W2139621750 countsByYear W21396217502018 @default.

• next