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- W2139719246 abstract "Summary Theileria mutans (Aitong) isolated from cattle exposed in the Narok District of Kenya and blood-passaged through cattle 8 times, appeared to have lost its original pathogenicity for cattle. It was demonstrated that the parasite was trans-stadially transmissible by the tick Amblyomma variegatum but not by Rhipicephalus appendiculatus . Four tick–bovine passages were made using A. variegatum , and infective parasites were also harvested from A. variegatum nymphs which had been fed for 5 days on rabbits. Blood containing piroplasms, or lymphoid cells infected with schizonts taken from cattle, at the 2nd tick–bovine passage were shown to be infective on inoculation. The course of the T. mutans infections in the cattle was studied. In tick-induced infections macroschizonts occurred transiently, persisting longest in circulating lymphoid cells. Microschizonts were rarely detected. The macroschizonts were morphologically distinct from those of other Theileria species described from East Africa. In tick-induced infections, the piroplasm parasitaemia increased rapidly and there was evidence of restored pathogenicity of the parasite since high piroplasm parasitaemias were associated with a marked anaemia." @default.
- W2139719246 created "2016-06-24" @default.
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- W2139719246 date "1978-02-01" @default.
- W2139719246 modified "2023-09-27" @default.
- W2139719246 title "Studies on the transmission and course of infection of a Kenyan strain of <i>Theileria mutans</i>" @default.
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- W2139719246 doi "https://doi.org/10.1017/s0031182000047430" @default.
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