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• W2139733196 abstract "Objective To estimate the relationship between structural changes in the heart and in the carotid arteries in hypertensives and to analyze the correlations between these structural changes and cardiovascular risk factors. Methods We studied 76 subjects (39 men and 27 women, mean age 45 ± 7 years) with mild-to-moderate untreated and uncomplicated hypertension. All of the subjects underwent ambulatory blood pressure monitoring, M-mode echocardiography for evaluation of their left ventricular mass and B-mode high-resolution ultrasonography to determine their carotid arterial wall thickness. Results The mean intimal plus medial thickness of the common carotid artery was found to be related significantly and independently to the left ventricular mass indexed by the body surface area. In multivariate analysis, age and the high-density lipoprotein cholesterol level were related strongly to the intimal plus medial thickness, whereas the clinic systolic blood pressure, average night-time systolic blood pressure and glycemia were the most important determinants of the left ventricular mass index. Logistic regression analysis suggested that the thickness of the posterior left ventricular wall was a stronger predictor of the carotid intima-medial thickness than were age and the high-density lipoprotein cholesterol level. Conclusion The carotid wall thickness and left ventricular mass of hypertensives are related independently; nevertheless the main determinants of structural cardiac and vascular changes are probably different. The mean intima-media thickness of the common carotid artery in mild-to-moderate untreated and uncomplicated hypertensive patients was related significantly and independently to the left ventricular wall thicknesses. Age and the high-density lipoprotein cholesterol level were the most important determinants of the mean intima-media thickness, whereas the clinic systolic blood pressure, average night-time systolic blood pressure and glycemia were strongly related to the left ventricular mass index." @default.
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• W2139733196 date "1997-08-01" @default.
• W2139733196 modified "2023-09-27" @default.
• W2139733196 title "Structural Changes in the Heart and Carotid Arteries in Hypertensive Patients Associated with Cardiovascular Risk Factors" @default.
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• W2139733196 doi "https://doi.org/10.1177/174182679700400409" @default.
• W2139733196 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9477207" @default.
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