Matches in SemOpenAlex for { <https://semopenalex.org/work/W2139760291> ?p ?o ?g. }
- W2139760291 endingPage "559" @default.
- W2139760291 startingPage "554" @default.
- W2139760291 abstract "To evaluate the effectiveness of serologic testing of blood donors for human immunodeficiency virus type 1 (HIV-1) and human T-cell lymphotropic virus types I and II (HTLV-I/II) infections and to estimate the risk for transmission of HIV-1 and HTLV-I/II by transfusion of seronegative blood from screened donors.A prospective multicenter cohort study of cardiac surgery patients who received multiple transfusions between 1985 and 1991.Cardiac surgery services of three large tertiary care hospitals.The study included 11,532 patients in three hospitals who had cardiovascular surgery.Incident HIV-1 and HTLV-I or HTLV-II infection.We detected two new HIV-1 infections among patients transfused with 120,312 units of blood components from seronegative donors. In each case a donor was detected on follow-up who had seroconverted since the donation. The HIV-1 infection rate was 0.0017% with an upper limit of the 95% CI of 0.0053%. Before donor screening for HTLV-I, transfusion of 51,026 units resulted in two HTLV-I infections (0.0039%) and four HTLV-II infections (0.0078%). After HTLV-I screening was instituted, one recipient was infected with HTLV-II among participants exposed to 69,272 units, a rate of 0.0014%. A corresponding HTLV-I/II-infected donor was found for this patient.Serologic screening of donors for antibodies to HIV-1 and HTLV-I coupled with exclusion of donors from groups having a relatively high risk for infection has led to a low incidence of transfusion-transmitted HIV-1 and HTLV-I/II infection in the United States. A small risk remains, however, despite these measures. We estimate the residual risk for HIV-1 and HTLV-II infection from transfusion of screened blood during the time of this study to be about 1 in 60,000 units." @default.
- W2139760291 created "2016-06-24" @default.
- W2139760291 creator A5003096950 @default.
- W2139760291 creator A5003492266 @default.
- W2139760291 creator A5004063560 @default.
- W2139760291 creator A5009228936 @default.
- W2139760291 creator A5010622215 @default.
- W2139760291 creator A5030551838 @default.
- W2139760291 creator A5033516475 @default.
- W2139760291 creator A5050381989 @default.
- W2139760291 creator A5050435343 @default.
- W2139760291 creator A5058894587 @default.
- W2139760291 creator A5059378390 @default.
- W2139760291 creator A5062646947 @default.
- W2139760291 creator A5073998761 @default.
- W2139760291 creator A5084156842 @default.
- W2139760291 date "1992-10-01" @default.
- W2139760291 modified "2023-10-04" @default.
- W2139760291 title "Transmission of Retroviruses from Seronegative Donors by Transfusion during Cardiac Surgery" @default.
- W2139760291 cites W1968873679 @default.
- W2139760291 cites W1975926758 @default.
- W2139760291 cites W1977282539 @default.
- W2139760291 cites W1978459598 @default.
- W2139760291 cites W1982090154 @default.
- W2139760291 cites W1984238033 @default.
- W2139760291 cites W1985330781 @default.
- W2139760291 cites W1993108804 @default.
- W2139760291 cites W1993868432 @default.
- W2139760291 cites W2010285743 @default.
- W2139760291 cites W2011893020 @default.
- W2139760291 cites W2015020283 @default.
- W2139760291 cites W2020684681 @default.
- W2139760291 cites W2033487936 @default.
- W2139760291 cites W2041804560 @default.
- W2139760291 cites W2042046631 @default.
- W2139760291 cites W2043401451 @default.
- W2139760291 cites W2053224942 @default.
- W2139760291 cites W2074996399 @default.
- W2139760291 cites W2077056408 @default.
- W2139760291 cites W2079986632 @default.
- W2139760291 cites W2092453476 @default.
- W2139760291 cites W2128175070 @default.
- W2139760291 cites W2131199430 @default.
- W2139760291 cites W2143110852 @default.
- W2139760291 cites W2316380084 @default.
- W2139760291 cites W2330379852 @default.
- W2139760291 cites W2333897803 @default.
- W2139760291 cites W2339678529 @default.
- W2139760291 cites W2397461250 @default.
- W2139760291 cites W2411539631 @default.
- W2139760291 cites W2474049457 @default.
- W2139760291 cites W60183410 @default.
- W2139760291 doi "https://doi.org/10.7326/0003-4819-117-7-554" @default.
- W2139760291 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1524329" @default.
- W2139760291 hasPublicationYear "1992" @default.
- W2139760291 type Work @default.
- W2139760291 sameAs 2139760291 @default.
- W2139760291 citedByCount "92" @default.
- W2139760291 countsByYear W21397602912013 @default.
- W2139760291 countsByYear W21397602912016 @default.
- W2139760291 countsByYear W21397602912017 @default.
- W2139760291 countsByYear W21397602912018 @default.
- W2139760291 countsByYear W21397602912020 @default.
- W2139760291 countsByYear W21397602912022 @default.
- W2139760291 crossrefType "journal-article" @default.
- W2139760291 hasAuthorship W2139760291A5003096950 @default.
- W2139760291 hasAuthorship W2139760291A5003492266 @default.
- W2139760291 hasAuthorship W2139760291A5004063560 @default.
- W2139760291 hasAuthorship W2139760291A5009228936 @default.
- W2139760291 hasAuthorship W2139760291A5010622215 @default.
- W2139760291 hasAuthorship W2139760291A5030551838 @default.
- W2139760291 hasAuthorship W2139760291A5033516475 @default.
- W2139760291 hasAuthorship W2139760291A5050381989 @default.
- W2139760291 hasAuthorship W2139760291A5050435343 @default.
- W2139760291 hasAuthorship W2139760291A5058894587 @default.
- W2139760291 hasAuthorship W2139760291A5059378390 @default.
- W2139760291 hasAuthorship W2139760291A5062646947 @default.
- W2139760291 hasAuthorship W2139760291A5073998761 @default.
- W2139760291 hasAuthorship W2139760291A5084156842 @default.
- W2139760291 hasConcept C119599485 @default.
- W2139760291 hasConcept C120665830 @default.
- W2139760291 hasConcept C121332964 @default.
- W2139760291 hasConcept C126322002 @default.
- W2139760291 hasConcept C127413603 @default.
- W2139760291 hasConcept C141071460 @default.
- W2139760291 hasConcept C159047783 @default.
- W2139760291 hasConcept C159654299 @default.
- W2139760291 hasConcept C188816634 @default.
- W2139760291 hasConcept C203014093 @default.
- W2139760291 hasConcept C2780014101 @default.
- W2139760291 hasConcept C45189115 @default.
- W2139760291 hasConcept C61511704 @default.
- W2139760291 hasConcept C71924100 @default.
- W2139760291 hasConcept C761482 @default.
- W2139760291 hasConceptScore W2139760291C119599485 @default.
- W2139760291 hasConceptScore W2139760291C120665830 @default.
- W2139760291 hasConceptScore W2139760291C121332964 @default.
- W2139760291 hasConceptScore W2139760291C126322002 @default.