Matches in SemOpenAlex for { <https://semopenalex.org/work/W2139792312> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2139792312 endingPage "104" @default.
- W2139792312 startingPage "73" @default.
- W2139792312 abstract "Dialysis adequacy targets are frequently difficult to achieve in large hemodialysis patients. Dual dialyzers can be used to improve clearance. It is unknown whether series or parallel configurations are superior. Objective: to improve urea clearance in large patients using parallel and series dual dialyzers. Patients and Methods: Eighteen large hemodialysis patients (mean 92.4 kg) were enrolled in a randomized, crossover trial to directly compare dual dialyzers in parallel and series configurations. Treatments times, blood flow rates, and dialysate flow rates were kept constant. Results: Compared to single dialyzers, parallel dual dialyzers increased the spKt/V from 1.25 +/− 0.22 to 1.43 +/− 0.29 (p < 0.003). Series dual dialyzers improved the spKt/V to 1.46 +/− 0.26 (p < 0.0003 compared to single dialyzer). The Kt/V and URR of dual dialyzers in parallel were not significantly different from dual dialyzers in series. Half of the subjects failed to meet the NKF-K/DOQI recommended adequacy target of spKt/V urea >/= 1.2 using a single dialyzer. With the use of dual dialyzers 83% of subjects achieved this adequacy target. Serum levels of ‘middle molecule,’ beta-2 microgobulin, were reduced 34% after two months of dual dialyzer therapy. Cost analysis estimates annual net savings of $1260 with dual dialyzer therapy, primarily from projected savings in inpatient expenses. Conclusions: In large hemodialysis patients, our study demonstrates that dual dialyzers in parallel and series are equally effective in improving urea clearance without prolonging dialysis treatment times." @default.
- W2139792312 created "2016-06-24" @default.
- W2139792312 creator A5012934502 @default.
- W2139792312 creator A5031637332 @default.
- W2139792312 creator A5084839043 @default.
- W2139792312 creator A5091058252 @default.
- W2139792312 date "2003-02-01" @default.
- W2139792312 modified "2023-09-26" @default.
- W2139792312 title "Comparison of Dual Dialyzers in Parallel and Series to Improve Urea Clearance in Large Hemodialysis Patients" @default.
- W2139792312 doi "https://doi.org/10.1046/j.1492-7535.2003.01211.x" @default.
- W2139792312 hasPublicationYear "2003" @default.
- W2139792312 type Work @default.
- W2139792312 sameAs 2139792312 @default.
- W2139792312 citedByCount "2" @default.
- W2139792312 countsByYear W21397923122018 @default.
- W2139792312 crossrefType "journal-article" @default.
- W2139792312 hasAuthorship W2139792312A5012934502 @default.
- W2139792312 hasAuthorship W2139792312A5031637332 @default.
- W2139792312 hasAuthorship W2139792312A5084839043 @default.
- W2139792312 hasAuthorship W2139792312A5091058252 @default.
- W2139792312 hasConcept C126894567 @default.
- W2139792312 hasConcept C127413603 @default.
- W2139792312 hasConcept C141071460 @default.
- W2139792312 hasConcept C142724271 @default.
- W2139792312 hasConcept C178790620 @default.
- W2139792312 hasConcept C185592680 @default.
- W2139792312 hasConcept C204787440 @default.
- W2139792312 hasConcept C27081682 @default.
- W2139792312 hasConcept C2778063415 @default.
- W2139792312 hasConcept C2779978075 @default.
- W2139792312 hasConcept C2780365088 @default.
- W2139792312 hasConcept C2780934675 @default.
- W2139792312 hasConcept C3019953569 @default.
- W2139792312 hasConcept C71924100 @default.
- W2139792312 hasConcept C78519656 @default.
- W2139792312 hasConcept C87813604 @default.
- W2139792312 hasConceptScore W2139792312C126894567 @default.
- W2139792312 hasConceptScore W2139792312C127413603 @default.
- W2139792312 hasConceptScore W2139792312C141071460 @default.
- W2139792312 hasConceptScore W2139792312C142724271 @default.
- W2139792312 hasConceptScore W2139792312C178790620 @default.
- W2139792312 hasConceptScore W2139792312C185592680 @default.
- W2139792312 hasConceptScore W2139792312C204787440 @default.
- W2139792312 hasConceptScore W2139792312C27081682 @default.
- W2139792312 hasConceptScore W2139792312C2778063415 @default.
- W2139792312 hasConceptScore W2139792312C2779978075 @default.
- W2139792312 hasConceptScore W2139792312C2780365088 @default.
- W2139792312 hasConceptScore W2139792312C2780934675 @default.
- W2139792312 hasConceptScore W2139792312C3019953569 @default.
- W2139792312 hasConceptScore W2139792312C71924100 @default.
- W2139792312 hasConceptScore W2139792312C78519656 @default.
- W2139792312 hasConceptScore W2139792312C87813604 @default.
- W2139792312 hasIssue "1" @default.
- W2139792312 hasLocation W21397923121 @default.
- W2139792312 hasOpenAccess W2139792312 @default.
- W2139792312 hasPrimaryLocation W21397923121 @default.
- W2139792312 hasRelatedWork W2053681242 @default.
- W2139792312 hasRelatedWork W2068348263 @default.
- W2139792312 hasRelatedWork W2068610051 @default.
- W2139792312 hasRelatedWork W2084032482 @default.
- W2139792312 hasRelatedWork W2088001981 @default.
- W2139792312 hasRelatedWork W2113858392 @default.
- W2139792312 hasRelatedWork W2127964363 @default.
- W2139792312 hasRelatedWork W2418431034 @default.
- W2139792312 hasRelatedWork W65157568 @default.
- W2139792312 hasRelatedWork W3148963004 @default.
- W2139792312 hasVolume "7" @default.
- W2139792312 isParatext "false" @default.
- W2139792312 isRetracted "false" @default.
- W2139792312 magId "2139792312" @default.
- W2139792312 workType "article" @default.