Matches in SemOpenAlex for { <https://semopenalex.org/work/W2139853313> ?p ?o ?g. }
- W2139853313 endingPage "9" @default.
- W2139853313 startingPage "1" @default.
- W2139853313 abstract "The glomerular filtration barrier is a highly specialized blood filtration interface that displays a high conductance to small and midsized solutes in plasma but retains relative impermeability to macromolecules. Its integrity is maintained by physicochemical and signalling interplay among its three core constituents—the glomerular endothelial cell, the basement membrane and visceral epithelial cell (podocyte). Understanding the pathomechanisms of inherited and acquired human diseases as well as experimental injury models of this barrier have helped to unravel this interdependence. Key among the consequences of interference with the integrity of the glomerular filtration barrier is the appearance of significant amounts of proteins in the urine. Proteinuria correlates with kidney disease progression and cardiovascular mortality. With specific reference to proteinuria in human and animal disease phenotypes, the following review explores the roles of the endothelial cell, glomerular basement membrane, and the podocyte and attempts to highlight examples of essential crosstalk within this barrier." @default.
- W2139853313 created "2016-06-24" @default.
- W2139853313 creator A5021913849 @default.
- W2139853313 creator A5052553547 @default.
- W2139853313 creator A5072561852 @default.
- W2139853313 date "2012-01-01" @default.
- W2139853313 modified "2023-09-30" @default.
- W2139853313 title "The Glomerular Filtration Barrier: Components and Crosstalk" @default.
- W2139853313 cites W1570583414 @default.
- W2139853313 cites W1968817172 @default.
- W2139853313 cites W1977847879 @default.
- W2139853313 cites W1978746677 @default.
- W2139853313 cites W1984720190 @default.
- W2139853313 cites W1985366772 @default.
- W2139853313 cites W1994247359 @default.
- W2139853313 cites W1997791761 @default.
- W2139853313 cites W2003818367 @default.
- W2139853313 cites W2012080977 @default.
- W2139853313 cites W2017210187 @default.
- W2139853313 cites W2019840171 @default.
- W2139853313 cites W2020498525 @default.
- W2139853313 cites W2023665881 @default.
- W2139853313 cites W2026103095 @default.
- W2139853313 cites W2028031291 @default.
- W2139853313 cites W2031098987 @default.
- W2139853313 cites W2045837374 @default.
- W2139853313 cites W2046394334 @default.
- W2139853313 cites W2048677414 @default.
- W2139853313 cites W2048818094 @default.
- W2139853313 cites W2049983920 @default.
- W2139853313 cites W2054225562 @default.
- W2139853313 cites W2054576721 @default.
- W2139853313 cites W2056901381 @default.
- W2139853313 cites W2060200294 @default.
- W2139853313 cites W2071323450 @default.
- W2139853313 cites W2075391935 @default.
- W2139853313 cites W2076166690 @default.
- W2139853313 cites W2077400092 @default.
- W2139853313 cites W2077531398 @default.
- W2139853313 cites W2082220621 @default.
- W2139853313 cites W2086096310 @default.
- W2139853313 cites W2086113903 @default.
- W2139853313 cites W2087564804 @default.
- W2139853313 cites W2087934100 @default.
- W2139853313 cites W2091652646 @default.
- W2139853313 cites W2092565468 @default.
- W2139853313 cites W2094011638 @default.
- W2139853313 cites W2094156578 @default.
- W2139853313 cites W2096707824 @default.
- W2139853313 cites W2098453796 @default.
- W2139853313 cites W2103586266 @default.
- W2139853313 cites W2103769076 @default.
- W2139853313 cites W2110153861 @default.
- W2139853313 cites W2111786954 @default.
- W2139853313 cites W2112307297 @default.
- W2139853313 cites W2113856093 @default.
- W2139853313 cites W2114446418 @default.
- W2139853313 cites W2121908444 @default.
- W2139853313 cites W2124565234 @default.
- W2139853313 cites W2126092981 @default.
- W2139853313 cites W2127923616 @default.
- W2139853313 cites W2134123153 @default.
- W2139853313 cites W2142895007 @default.
- W2139853313 cites W2145356697 @default.
- W2139853313 cites W2146696453 @default.
- W2139853313 cites W2148171171 @default.
- W2139853313 cites W2148820339 @default.
- W2139853313 cites W2154220060 @default.
- W2139853313 cites W2156196642 @default.
- W2139853313 cites W2159098596 @default.
- W2139853313 cites W2159988004 @default.
- W2139853313 cites W2160588155 @default.
- W2139853313 cites W2162161302 @default.
- W2139853313 cites W2163543028 @default.
- W2139853313 cites W2168287443 @default.
- W2139853313 cites W2169076924 @default.
- W2139853313 cites W2170346765 @default.
- W2139853313 cites W2617227629 @default.
- W2139853313 cites W2942956196 @default.
- W2139853313 cites W4235538415 @default.
- W2139853313 cites W4239079406 @default.
- W2139853313 cites W4239155810 @default.
- W2139853313 cites W4248227512 @default.
- W2139853313 cites W4302317755 @default.
- W2139853313 doi "https://doi.org/10.1155/2012/749010" @default.
- W2139853313 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3426247" @default.
- W2139853313 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22934182" @default.
- W2139853313 hasPublicationYear "2012" @default.
- W2139853313 type Work @default.
- W2139853313 sameAs 2139853313 @default.
- W2139853313 citedByCount "85" @default.
- W2139853313 countsByYear W21398533132013 @default.
- W2139853313 countsByYear W21398533132014 @default.
- W2139853313 countsByYear W21398533132015 @default.
- W2139853313 countsByYear W21398533132016 @default.
- W2139853313 countsByYear W21398533132017 @default.
- W2139853313 countsByYear W21398533132018 @default.
- W2139853313 countsByYear W21398533132019 @default.