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• W2140063757 abstract "A child or neonate presenting with fever is a common medical problem. To differentiate between those with a severe bacterial infection and those with a localised bacterial or a viral infection can be a challenge. This review provides an overview of neonatal and paediatric studies that assess the use of procalcitonin as an early marker of bacterial infection. Procalcitonin is an excellent marker for severe, invasive bacterial infection in children. However, the use of procalcitonin in the diagnosis of neonatal bacterial infection is complicated, but if correctly used procalcitonin results in a higher specificity than C-reactive protein. In addition, procalcitonin has been shown to correlate with severity of disease (urinary tract infections and sepsis), and can therefore be used as a prognostic marker. Procalcitonin is therefore a useful additional tool for the diagnosis of bacterial disease in neonates and children. A child or neonate presenting with fever is a common medical problem. To differentiate between those with a severe bacterial infection and those with a localised bacterial or a viral infection can be a challenge. This review provides an overview of neonatal and paediatric studies that assess the use of procalcitonin as an early marker of bacterial infection. Procalcitonin is an excellent marker for severe, invasive bacterial infection in children. However, the use of procalcitonin in the diagnosis of neonatal bacterial infection is complicated, but if correctly used procalcitonin results in a higher specificity than C-reactive protein. In addition, procalcitonin has been shown to correlate with severity of disease (urinary tract infections and sepsis), and can therefore be used as a prognostic marker. Procalcitonin is therefore a useful additional tool for the diagnosis of bacterial disease in neonates and children." @default.
• W2140063757 created "2016-06-24" @default.
• W2140063757 creator A5005198723 @default.
• W2140063757 creator A5021199351 @default.
• W2140063757 creator A5064245613 @default.
• W2140063757 date "2004-10-01" @default.
• W2140063757 modified "2023-10-14" @default.
• W2140063757 title "Procalcitonin as an early marker of infection in neonates and children" @default.
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• W2140063757 doi "https://doi.org/10.1016/s1473-3099(04)01146-6" @default.
• W2140063757 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15451490" @default.
• W2140063757 hasPublicationYear "2004" @default.
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