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- W2140193328 abstract "Cytokines, chemokines and other soluble factors play important roles in mediating inflammatory responses, tissue repair and acute and chronic rejection of transplanted grafts. To determine the function of these molecules in chronic progresses of graft accommodation and rejection 1 Gerasimidi A. Sheehan K.C. Schreiber R.D. Lacy P.E. Tumor necrosis factor-alpha prevents rejection of islet xenografts (rat to mouse). Diabetes. 1993; 42: 651-657 Crossref PubMed Scopus (15) Google Scholar , 2 Vallera D.A. Taylor P.A. Widmer M.B. Blazar B.R. Interleukin-1 alpha-mediated promotion of long-term alloengraftment and short-term neutrophil expansion does not require the presence of either donor or host T cells. Transplantation. 1996; 62: 636-642 Crossref PubMed Scopus (3) Google Scholar , 3 Boehler A. Chamberlain D. Xing Z. et al. Adenovirus-mediated interleukin-10 gene transfer inhibits post-transplant fibrous airway obliteration in an animal model of bronchiolitis obliterans. Hum Gene Ther. 1998; 9: 541-551 Crossref PubMed Scopus (70) Google Scholar , 4 Suga M. Maclean A.A. Keshavjee S. Fischer S. Moreira J.M. Liu M. RANTES plays an important role in the evolution of allograft transplant-induced fibrous airway obliteration. Am J Respir Crit Care Med. 2000; 162: 1940-1948 Crossref PubMed Scopus (45) Google Scholar and other diseases, 5 Endo H. Akahoshi T. Nishimura A. et al. Experimental arthritis induced by continuous infusion of IL-8 into rabbit knee joints. Clin Exp Immunol. 1994; 96: 31-35 Crossref PubMed Scopus (46) Google Scholar mini-osmotic pumps have been used to deliver these molecules at the desired location and concentrations over days or weeks. One of the major concerns is the stability of these molecules at body temperature, especially for a relatively long period. This simple but important question is not often addressed in the literature." @default.
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- W2140193328 date "2005-04-01" @default.
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- W2140193328 title "Instability of cytokines at body temperature" @default.
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- W2140193328 doi "https://doi.org/10.1016/j.healun.2003.11.403" @default.
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