Matches in SemOpenAlex for { <https://semopenalex.org/work/W2140200200> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2140200200 endingPage "60" @default.
- W2140200200 startingPage "2551" @default.
- W2140200200 abstract "Human basal cell epithelioma was shown to contain collagenolytic enzymes. With the use of reconstituted radioactive collagen substrate, the crude enzyme (tumor homogenate) was shown to release radioactivity 4 to 70 times greater than the release from normal control skin. Disc electrophoresis of the same incubation mixture demonstrated degradation products of collagen such as αA and βA. Kinetic studies with the pooled specimens revealed a linear increase of collagenolytic activity with respect to crude enzyme concentration or the length of incubation time. The optimal pH ranged between 7 and 8.5. Normal human serum, cysteine, and ethylenediaminetetraacetate significantly inhibited the enzyme activity, whereas a trypsin inhibitor (soybean) did not. Viscometric studies demonstrated that basal cell epithelioma crude enzyme decreased the specific viscosity of acid-soluble calf skin tropocollagen. Polarimetric studies indicated that, at temperatures below the denaturation temperature of tropocollagen, the ordered structure of the triple helical macromolecule was not affected during this treatment. The denaturation temperature of tropocollagen was decreased by 5° as a result of incubation with basal cell epithelioma homogenates." @default.
- W2140200200 created "2016-06-24" @default.
- W2140200200 creator A5015519725 @default.
- W2140200200 creator A5028781129 @default.
- W2140200200 creator A5075964955 @default.
- W2140200200 date "1972-11-01" @default.
- W2140200200 modified "2023-09-23" @default.
- W2140200200 title "Effect of collagenolytic activity in basal cell epithelioma of the skin on reconstituted collagen and physical properties and kinetics of the crude enzyme." @default.
- W2140200200 cites W1483815930 @default.
- W2140200200 cites W1966567387 @default.
- W2140200200 cites W1994709083 @default.
- W2140200200 cites W2002193327 @default.
- W2140200200 cites W2009827512 @default.
- W2140200200 cites W2012347687 @default.
- W2140200200 cites W2015549719 @default.
- W2140200200 cites W2016784327 @default.
- W2140200200 cites W2020188765 @default.
- W2140200200 cites W2039943972 @default.
- W2140200200 cites W2046954838 @default.
- W2140200200 cites W2075195713 @default.
- W2140200200 cites W2078207402 @default.
- W2140200200 cites W2086460205 @default.
- W2140200200 cites W2090244113 @default.
- W2140200200 cites W2095337996 @default.
- W2140200200 cites W2102726536 @default.
- W2140200200 cites W2113652248 @default.
- W2140200200 cites W2140931363 @default.
- W2140200200 cites W2321264774 @default.
- W2140200200 cites W2334520771 @default.
- W2140200200 cites W2466003717 @default.
- W2140200200 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4343237" @default.
- W2140200200 hasPublicationYear "1972" @default.
- W2140200200 type Work @default.
- W2140200200 sameAs 2140200200 @default.
- W2140200200 citedByCount "30" @default.
- W2140200200 countsByYear W21402002002018 @default.
- W2140200200 crossrefType "journal-article" @default.
- W2140200200 hasAuthorship W2140200200A5015519725 @default.
- W2140200200 hasAuthorship W2140200200A5028781129 @default.
- W2140200200 hasAuthorship W2140200200A5075964955 @default.
- W2140200200 hasConcept C126322002 @default.
- W2140200200 hasConcept C13965031 @default.
- W2140200200 hasConcept C153911025 @default.
- W2140200200 hasConcept C16311235 @default.
- W2140200200 hasConcept C181199279 @default.
- W2140200200 hasConcept C185592680 @default.
- W2140200200 hasConcept C25642318 @default.
- W2140200200 hasConcept C2776923230 @default.
- W2140200200 hasConcept C2780340462 @default.
- W2140200200 hasConcept C2908762713 @default.
- W2140200200 hasConcept C3019992690 @default.
- W2140200200 hasConcept C55493867 @default.
- W2140200200 hasConcept C71924100 @default.
- W2140200200 hasConcept C86803240 @default.
- W2140200200 hasConceptScore W2140200200C126322002 @default.
- W2140200200 hasConceptScore W2140200200C13965031 @default.
- W2140200200 hasConceptScore W2140200200C153911025 @default.
- W2140200200 hasConceptScore W2140200200C16311235 @default.
- W2140200200 hasConceptScore W2140200200C181199279 @default.
- W2140200200 hasConceptScore W2140200200C185592680 @default.
- W2140200200 hasConceptScore W2140200200C25642318 @default.
- W2140200200 hasConceptScore W2140200200C2776923230 @default.
- W2140200200 hasConceptScore W2140200200C2780340462 @default.
- W2140200200 hasConceptScore W2140200200C2908762713 @default.
- W2140200200 hasConceptScore W2140200200C3019992690 @default.
- W2140200200 hasConceptScore W2140200200C55493867 @default.
- W2140200200 hasConceptScore W2140200200C71924100 @default.
- W2140200200 hasConceptScore W2140200200C86803240 @default.
- W2140200200 hasIssue "11" @default.
- W2140200200 hasLocation W21402002001 @default.
- W2140200200 hasOpenAccess W2140200200 @default.
- W2140200200 hasPrimaryLocation W21402002001 @default.
- W2140200200 hasRelatedWork W1963954076 @default.
- W2140200200 hasRelatedWork W1992151770 @default.
- W2140200200 hasRelatedWork W2025170744 @default.
- W2140200200 hasRelatedWork W2091165889 @default.
- W2140200200 hasRelatedWork W2312278035 @default.
- W2140200200 hasRelatedWork W2318749532 @default.
- W2140200200 hasRelatedWork W2398763624 @default.
- W2140200200 hasRelatedWork W2949730710 @default.
- W2140200200 hasRelatedWork W2951652748 @default.
- W2140200200 hasRelatedWork W2953182654 @default.
- W2140200200 hasVolume "32" @default.
- W2140200200 isParatext "false" @default.
- W2140200200 isRetracted "false" @default.
- W2140200200 magId "2140200200" @default.
- W2140200200 workType "article" @default.