Matches in SemOpenAlex for { <https://semopenalex.org/work/W2140200828> ?p ?o ?g. }
- W2140200828 endingPage "18498" @default.
- W2140200828 startingPage "18493" @default.
- W2140200828 abstract "The ABO histo-blood group, the critical determinant of transfusion incompatibility, was the first genetic polymorphism discovered in humans. Remarkably, ABO antigens are also polymorphic in many other primates, with the same two amino acid changes responsible for A and B specificity in all species sequenced to date. Whether this recurrence of A and B antigens is the result of an ancient polymorphism maintained across species or due to numerous, more recent instances of convergent evolution has been debated for decades, with a current consensus in support of convergent evolution. We show instead that genetic variation data in humans and gibbons as well as in Old World Monkeys are inconsistent with a model of convergent evolution and support the hypothesis of an ancient, multi-allelic polymorphism of which some alleles are shared by descent among species. These results demonstrate that the ABO polymorphism is a trans-species polymorphism among distantly related species and has remained under balancing selection for tens of millions of years, to date, the only such example in Hominoids and Old World Monkeys outside of the Major Histocompatibility Complex." @default.
- W2140200828 created "2016-06-24" @default.
- W2140200828 creator A5001631473 @default.
- W2140200828 creator A5006512152 @default.
- W2140200828 creator A5027542369 @default.
- W2140200828 creator A5027758614 @default.
- W2140200828 creator A5029261729 @default.
- W2140200828 creator A5035131612 @default.
- W2140200828 creator A5039579959 @default.
- W2140200828 creator A5041435831 @default.
- W2140200828 creator A5045081776 @default.
- W2140200828 creator A5061979946 @default.
- W2140200828 creator A5067673155 @default.
- W2140200828 creator A5070036803 @default.
- W2140200828 date "2012-09-25" @default.
- W2140200828 modified "2023-10-15" @default.
- W2140200828 title "The ABO blood group is a trans-species polymorphism in primates" @default.
- W2140200828 cites W1540123184 @default.
- W2140200828 cites W1776365146 @default.
- W2140200828 cites W1969770412 @default.
- W2140200828 cites W1971000305 @default.
- W2140200828 cites W1971307410 @default.
- W2140200828 cites W1974193753 @default.
- W2140200828 cites W1977169047 @default.
- W2140200828 cites W1990103381 @default.
- W2140200828 cites W1994332522 @default.
- W2140200828 cites W2005856304 @default.
- W2140200828 cites W2006852302 @default.
- W2140200828 cites W2014094060 @default.
- W2140200828 cites W2017114835 @default.
- W2140200828 cites W2026828421 @default.
- W2140200828 cites W2030288246 @default.
- W2140200828 cites W2030336958 @default.
- W2140200828 cites W2031082289 @default.
- W2140200828 cites W2039435867 @default.
- W2140200828 cites W2046414350 @default.
- W2140200828 cites W2050656709 @default.
- W2140200828 cites W2055574416 @default.
- W2140200828 cites W2056592635 @default.
- W2140200828 cites W2074357867 @default.
- W2140200828 cites W2079057292 @default.
- W2140200828 cites W2089868147 @default.
- W2140200828 cites W2093806758 @default.
- W2140200828 cites W2094841682 @default.
- W2140200828 cites W2102751840 @default.
- W2140200828 cites W2110335151 @default.
- W2140200828 cites W2111534865 @default.
- W2140200828 cites W2112442294 @default.
- W2140200828 cites W2113432260 @default.
- W2140200828 cites W2115011276 @default.
- W2140200828 cites W2117123843 @default.
- W2140200828 cites W2125094990 @default.
- W2140200828 cites W2130783116 @default.
- W2140200828 cites W2143150075 @default.
- W2140200828 cites W2143562461 @default.
- W2140200828 cites W2144820135 @default.
- W2140200828 cites W2146058063 @default.
- W2140200828 cites W2152015607 @default.
- W2140200828 cites W2153309528 @default.
- W2140200828 cites W2153631698 @default.
- W2140200828 cites W2157394513 @default.
- W2140200828 cites W2167470356 @default.
- W2140200828 cites W2169537018 @default.
- W2140200828 cites W2170598161 @default.
- W2140200828 cites W2171777347 @default.
- W2140200828 cites W5852198 @default.
- W2140200828 cites W594560177 @default.
- W2140200828 cites W87593511 @default.
- W2140200828 doi "https://doi.org/10.1073/pnas.1210603109" @default.
- W2140200828 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3494955" @default.
- W2140200828 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23091028" @default.
- W2140200828 hasPublicationYear "2012" @default.
- W2140200828 type Work @default.
- W2140200828 sameAs 2140200828 @default.
- W2140200828 citedByCount "130" @default.
- W2140200828 countsByYear W21402008282012 @default.
- W2140200828 countsByYear W21402008282013 @default.
- W2140200828 countsByYear W21402008282014 @default.
- W2140200828 countsByYear W21402008282015 @default.
- W2140200828 countsByYear W21402008282016 @default.
- W2140200828 countsByYear W21402008282017 @default.
- W2140200828 countsByYear W21402008282018 @default.
- W2140200828 countsByYear W21402008282019 @default.
- W2140200828 countsByYear W21402008282020 @default.
- W2140200828 countsByYear W21402008282021 @default.
- W2140200828 countsByYear W21402008282022 @default.
- W2140200828 countsByYear W21402008282023 @default.
- W2140200828 crossrefType "journal-article" @default.
- W2140200828 hasAuthorship W2140200828A5001631473 @default.
- W2140200828 hasAuthorship W2140200828A5006512152 @default.
- W2140200828 hasAuthorship W2140200828A5027542369 @default.
- W2140200828 hasAuthorship W2140200828A5027758614 @default.
- W2140200828 hasAuthorship W2140200828A5029261729 @default.
- W2140200828 hasAuthorship W2140200828A5035131612 @default.
- W2140200828 hasAuthorship W2140200828A5039579959 @default.
- W2140200828 hasAuthorship W2140200828A5041435831 @default.
- W2140200828 hasAuthorship W2140200828A5045081776 @default.
- W2140200828 hasAuthorship W2140200828A5061979946 @default.