Matches in SemOpenAlex for { <https://semopenalex.org/work/W2140218239> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2140218239 endingPage "205" @default.
- W2140218239 startingPage "205" @default.
- W2140218239 abstract "Inversion at the exocyclic nitrogen in 3-acetoxyaminoquinazolinones, e.g. 2 is slow on the NMR time-scale. The associated inversion barrier could not be measured directly by NMR spectroscopy because of the thermal instability of compound 2. However, the corresponding inversion barriers for 3-isopropoxyaminoquinazolinone 5 and 3-tert-butoxyaminoquinazolinone 6, prepared by reaction of 3-acetoxyaminoquinazolinone 2 with titanium(IV) isopropoxide and titanium(IV)tert-butoxide respectively, suggest that it is sufficiently low for the rate of inversion to be fast relative to the rate of aziridination of alkenes using reagent 2. This conclusion is supported by the preparation of diastereoisomers of 3-acetoxyaminoquinazolinones 3, 16 and 21 at –20 °C and by monitoring their relative rates of aziridination of cinnamyl alcohol (by 3), and styrene (by 16) and of intramolecular aziridination (for 21) by NMR spectroscopy. In no case was there any change in the ratio of these diastereoisomers as the aziridinations progressed implying that interconversion between them was faster than the rates at which they reacted individually with the respective alkene." @default.
- W2140218239 created "2016-06-24" @default.
- W2140218239 creator A5033161439 @default.
- W2140218239 creator A5067094367 @default.
- W2140218239 date "1996-01-01" @default.
- W2140218239 modified "2023-09-25" @default.
- W2140218239 title "3-Acetoxyaminoquinazolin-4(3H)-ones as aziridinating agents: relative rate of inversion at the exocyclic nitrogen" @default.
- W2140218239 cites W1458703663 @default.
- W2140218239 cites W1964843374 @default.
- W2140218239 cites W2007821853 @default.
- W2140218239 cites W2018274125 @default.
- W2140218239 cites W2041848515 @default.
- W2140218239 cites W2062878956 @default.
- W2140218239 doi "https://doi.org/10.1039/p29960000205" @default.
- W2140218239 hasPublicationYear "1996" @default.
- W2140218239 type Work @default.
- W2140218239 sameAs 2140218239 @default.
- W2140218239 citedByCount "10" @default.
- W2140218239 countsByYear W21402182392015 @default.
- W2140218239 countsByYear W21402182392019 @default.
- W2140218239 crossrefType "journal-article" @default.
- W2140218239 hasAuthorship W2140218239A5033161439 @default.
- W2140218239 hasAuthorship W2140218239A5067094367 @default.
- W2140218239 hasConcept C122873222 @default.
- W2140218239 hasConcept C138716334 @default.
- W2140218239 hasConcept C155647269 @default.
- W2140218239 hasConcept C15920480 @default.
- W2140218239 hasConcept C161790260 @default.
- W2140218239 hasConcept C178790620 @default.
- W2140218239 hasConcept C185592680 @default.
- W2140218239 hasConcept C2776254738 @default.
- W2140218239 hasConcept C2777566558 @default.
- W2140218239 hasConcept C40875361 @default.
- W2140218239 hasConcept C506065880 @default.
- W2140218239 hasConcept C521977710 @default.
- W2140218239 hasConcept C537208039 @default.
- W2140218239 hasConcept C66974803 @default.
- W2140218239 hasConcept C75079739 @default.
- W2140218239 hasConceptScore W2140218239C122873222 @default.
- W2140218239 hasConceptScore W2140218239C138716334 @default.
- W2140218239 hasConceptScore W2140218239C155647269 @default.
- W2140218239 hasConceptScore W2140218239C15920480 @default.
- W2140218239 hasConceptScore W2140218239C161790260 @default.
- W2140218239 hasConceptScore W2140218239C178790620 @default.
- W2140218239 hasConceptScore W2140218239C185592680 @default.
- W2140218239 hasConceptScore W2140218239C2776254738 @default.
- W2140218239 hasConceptScore W2140218239C2777566558 @default.
- W2140218239 hasConceptScore W2140218239C40875361 @default.
- W2140218239 hasConceptScore W2140218239C506065880 @default.
- W2140218239 hasConceptScore W2140218239C521977710 @default.
- W2140218239 hasConceptScore W2140218239C537208039 @default.
- W2140218239 hasConceptScore W2140218239C66974803 @default.
- W2140218239 hasConceptScore W2140218239C75079739 @default.
- W2140218239 hasIssue "2" @default.
- W2140218239 hasLocation W21402182391 @default.
- W2140218239 hasOpenAccess W2140218239 @default.
- W2140218239 hasPrimaryLocation W21402182391 @default.
- W2140218239 hasRelatedWork W1992325888 @default.
- W2140218239 hasRelatedWork W2019571757 @default.
- W2140218239 hasRelatedWork W2035317768 @default.
- W2140218239 hasRelatedWork W2039988297 @default.
- W2140218239 hasRelatedWork W2086191285 @default.
- W2140218239 hasRelatedWork W2159434458 @default.
- W2140218239 hasRelatedWork W2400736630 @default.
- W2140218239 hasRelatedWork W2952256733 @default.
- W2140218239 hasRelatedWork W2953155228 @default.
- W2140218239 hasRelatedWork W1992894787 @default.
- W2140218239 isParatext "false" @default.
- W2140218239 isRetracted "false" @default.
- W2140218239 magId "2140218239" @default.
- W2140218239 workType "article" @default.