Matches in SemOpenAlex for { <https://semopenalex.org/work/W2140266936> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2140266936 endingPage "320" @default.
- W2140266936 startingPage "309" @default.
- W2140266936 abstract "ABSTRACT The total iodine content and the content of iodocompounds in the thyroid gland were studied in 9 patients with autoimmune thyroiditis. The thyroids were labelled in vivo with radioactive iodine before surgical biopsy. Five grams of tissue were homogenized and the iodocompounds were separated both by paper chromatography and on a cellulose column. The distribution profile of both the radioactive and the stable compounds was determined. The thyroid tissue contained on an average 11.0 ± 8.0 ( sd ) per cent of radioactive and 15.0 ± 9.4 per cent of stable iodothyronines. The MIT/DIT ratio was 1.16 ± 0.26 for the radioactive and 0.92 ± 0.30 for the stable compounds. Clinically evident hypothyroidism occurred only in patients with a very low iodine content and was not correlated with the proportion of iodothyronines found in the thyroid tissue. For instance, in two hypothyroid patients the iodothyronines corresponded to about 20 per cent of the iodocompounds of the tissue. These findings suggest that iodine depletion of the thyroid gland plays an important role in the development of clinical hypothyroidism in autoimmune thyroiditis and that up to a very late stage of the disease the thyroid is evidently capable of producing iodothyronines in fairly normal proportions." @default.
- W2140266936 created "2016-06-24" @default.
- W2140266936 creator A5037168218 @default.
- W2140266936 creator A5045667911 @default.
- W2140266936 creator A5057406722 @default.
- W2140266936 creator A5059250631 @default.
- W2140266936 creator A5089671702 @default.
- W2140266936 date "1972-02-01" @default.
- W2140266936 modified "2023-10-12" @default.
- W2140266936 title "THE CONTENT OF THYROID HORMONES AND OTHER IODINATED COMPOUNDS IN THYROID TISSUE IN AUTOIMMUNE THYROIDITIS" @default.
- W2140266936 doi "https://doi.org/10.1530/acta.0.0690309" @default.
- W2140266936 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5066840" @default.
- W2140266936 hasPublicationYear "1972" @default.
- W2140266936 type Work @default.
- W2140266936 sameAs 2140266936 @default.
- W2140266936 citedByCount "7" @default.
- W2140266936 crossrefType "journal-article" @default.
- W2140266936 hasAuthorship W2140266936A5037168218 @default.
- W2140266936 hasAuthorship W2140266936A5045667911 @default.
- W2140266936 hasAuthorship W2140266936A5057406722 @default.
- W2140266936 hasAuthorship W2140266936A5059250631 @default.
- W2140266936 hasAuthorship W2140266936A5089671702 @default.
- W2140266936 hasConcept C126322002 @default.
- W2140266936 hasConcept C134018914 @default.
- W2140266936 hasConcept C158479217 @default.
- W2140266936 hasConcept C178790620 @default.
- W2140266936 hasConcept C185592680 @default.
- W2140266936 hasConcept C2776362883 @default.
- W2140266936 hasConcept C2778696486 @default.
- W2140266936 hasConcept C2908975369 @default.
- W2140266936 hasConcept C2993291352 @default.
- W2140266936 hasConcept C526584372 @default.
- W2140266936 hasConcept C539932907 @default.
- W2140266936 hasConcept C71315377 @default.
- W2140266936 hasConcept C71924100 @default.
- W2140266936 hasConceptScore W2140266936C126322002 @default.
- W2140266936 hasConceptScore W2140266936C134018914 @default.
- W2140266936 hasConceptScore W2140266936C158479217 @default.
- W2140266936 hasConceptScore W2140266936C178790620 @default.
- W2140266936 hasConceptScore W2140266936C185592680 @default.
- W2140266936 hasConceptScore W2140266936C2776362883 @default.
- W2140266936 hasConceptScore W2140266936C2778696486 @default.
- W2140266936 hasConceptScore W2140266936C2908975369 @default.
- W2140266936 hasConceptScore W2140266936C2993291352 @default.
- W2140266936 hasConceptScore W2140266936C526584372 @default.
- W2140266936 hasConceptScore W2140266936C539932907 @default.
- W2140266936 hasConceptScore W2140266936C71315377 @default.
- W2140266936 hasConceptScore W2140266936C71924100 @default.
- W2140266936 hasIssue "2" @default.
- W2140266936 hasLocation W21402669361 @default.
- W2140266936 hasLocation W21402669362 @default.
- W2140266936 hasOpenAccess W2140266936 @default.
- W2140266936 hasPrimaryLocation W21402669361 @default.
- W2140266936 hasRelatedWork W1599095214 @default.
- W2140266936 hasRelatedWork W2010645160 @default.
- W2140266936 hasRelatedWork W2039456755 @default.
- W2140266936 hasRelatedWork W2040527492 @default.
- W2140266936 hasRelatedWork W2155312245 @default.
- W2140266936 hasRelatedWork W2170976902 @default.
- W2140266936 hasRelatedWork W2409340316 @default.
- W2140266936 hasRelatedWork W2485894079 @default.
- W2140266936 hasRelatedWork W2748952813 @default.
- W2140266936 hasRelatedWork W4245740351 @default.
- W2140266936 hasVolume "69" @default.
- W2140266936 isParatext "false" @default.
- W2140266936 isRetracted "false" @default.
- W2140266936 magId "2140266936" @default.
- W2140266936 workType "article" @default.