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- W2140266957 abstract "There are relatively few data reported on specific features of drug pharmacokinetics (PK) and pharmacodynamics in pregnancy compared to the non-pregnant state. Changes in maternal physiology and metabolic processes during pregnancy effect on PK and show that standard adult dosing is likely to be incorrect during pregnancy. Physiology-based pharmacokinetic (PBPK) model could be used to evaluate different dosing regimens for pregnant women and to correctly predict drug exposure and response on the personal level." @default.
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- W2140266957 date "2014-01-01" @default.
- W2140266957 modified "2023-09-25" @default.
- W2140266957 title "[Peculiarities and clinical significance of drug pharmacokinetics and pharmacodynamics during pregnancy]." @default.
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